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Dr. Shefier, Donald Greene

Michael Adao congratulates Dr. Lee. Bruce Middendorf, Daniel Botsford, )ohn Clark
and Tone Johnson give their approval.

Sophomores Honor Faculty
Five faculty at the Medical School, who have not only offered good
teaching but have unselfishly responded to the needs of the stu­
dents, were awarded plaques by the sophomore class.
They are Dr. Harold Brody, professor and chairman of the
department of anatomy; Dr. Alexander C. Brownie, research associ­
ate professor of pathology and professor of biochemistry; Dr. Peter
K. Gessner, associate professor of pharmacology; Dr. Joseph C. Lee,
professor of anatomy and research associate professor of surgery
(neurosurgery); Dr. John B. Sheffer, clinical associate professor and
acting chairman of pathology.
Inscribed on the plaques presented to the five whose outstand­
ing efforts may have gone unrecognized is "for insight and dedica­
tion to teaching, from the Medical Class 1974."

Dr. Brownie, Thomas Varecka
Dr. Brody

Congratulations," said class president Bruce Middendorf, "for
not only excelling in your specialty but for effectively communicat­
ing that knowledge to us as students. Your teaching has not only
been good but it has been excellent." The unanimity of agreement
among his classmates was obvious.
Expressed by the recipients was the hope that this kind of
recognition by students for good teaching would become a tradition
here at the Medical School.•

Winter 1972
Volume 6, Number 4

THE BUFFALO PHYSICIAN
Published by the School of Medicine, State University of New York at Buffalo

IN THIS ISSUE
Faculty Honored

EDITORIAL BOARD
Editor
ROBERT S. McGRANAHAN
Managing Editor
MARION MARIONOWSKY
Photography
HUGO H. UNGER

(inside front cover)

2
5
6
7
8

by President Robert L. Ketter

EDWARD NOWAK
Medical Illustrator
MELFORD J. DIEDRICK
Graphic Artists
RICHARD MACAKANJA
DONALD E. WATKINS
Secretary
FLORENCE MEYER

CONSULTANTS
President, Medical Alumni Association
DR. JOHN J. O'BRIEN
President, Alumni Participating Fund for
Medical Education
DR. MARVIN BLOOM
Vice President, Faculty of Health Sciences
DR. CLYDE L. RANDALL
Vice President, University Foundation
JOHN C. CARTER
Director of Public Information
JAMES DeSANTIS
Director of Medical Alumni Affairs
DAVID K. MICHAEL
Director of University Publications
PAUL L. KANE
Vice President for University Relations
DR. A. WESTLEY ROWLAND

Pacemakers
Alumni Receptions
SLE Test
Children's Hospital
University/Hospital Partnership

12
13
15
17
18
19
20
22
23
24
25
26
28
29
30
33
34
35
37
39
40
41
42
43
44
45
46
48
49
50
52
53
54
55
56
60
62
63
66
70

Drug Abuse
Roswell Park/Psychiatry Director
Rural Health Care
Prenatals
Gonorrhea Test
Gyn/Ob Head/Chinese Student
Teaching Techniques
Continuing Medical Education
Community-University Day
Polluted Waters
New Journal/Psychiatry Grant
Dr. George Thorn
Moral Issue
BGH Expansion
Allergic Disease Center
LARMP/Microbiology Grants
Hallucinogens
Dermatology Chairman
The 1976 Class
Family Practice/Dr. Murphy
Surgery Chairman
Dr. Regan/Scholarships
First Complex Hormone
Dr. Vaughan Lab/Health Center
Infectious Diseases
VA Hospital Director
Lackawanna Health Center
Health Resources/Dr. LaPaglia
Surgery
VA Drug Treatment
Mental Health
10,000 Mile Cruise
Medical Van
New North Campus
Heart/Lung Studies
Swimming Analysis
Faculty Promotions
The Classes
People
In Memoriam

The graphic cover design by Richard Macakanja symbolizes the holiday season.
THE BUFFALO PHYSICIAN, Winter 1972 — Volume 6, Number 4, published quarterly
Spring, Summer, Fall, Winter — by the School of Medicine, State University of New
York at Buffalo, 3435 Main Street, Buffalo, New York 14214. Second class postage
paid at Buffalo, New York. Please notify us of change of address. Copyright 1972
by The Buffalo Physician.

Over 200 investigators
from around the world
attended a postgraduate
symposium on cardiac
pacing held in the Medi­
cal School in 7965. Dr.
Chardack "demonstrates"
in the laboratory.

Pioneers in PACEMAKERS

One of the first devices developed by
the team.

T w o PIONEERS IN the development of battery-powered pace­
makers made history again by implanting the first nuclear-powered
device in this country last July. They are Drs. William M. Chardack,
chief of thoracic surgery, and Andrew A. Gage, chief of surgery at
the Veterans Administration Hospital, who also are associate pro­
fessor and professor of surgery respectively at the Medical School.
The hospital was the first in the nation to be granted a license by
the U. S. Atomic Energy Commission to use the radioisotope pace­
maker. Four patients, who have now been operated on, have made
uneventful recoveries.
The history of the Veterans Administration Hospital's surgical
service and its research laboratory lists many "surgical firsts." In
1950, the initial year of hospital operation, Drs. Chardack and James
D. MacCallum performed the first successful resection of a "Pancoast Tumor followed by radiation therapy. This rapidly fatal type
of cancer of the apex of the lung until then was thought to be
incurable and inoperable. The patient, who lived for over five years,
died from an unrelated disease.
Following reports by the two surgeons in 1953 and 1955, the
combination of surgery/radiotherapy, was accepted as the standard
treatment for this condition. It has yielded a significant number of
cures.
In 1953 a resection of the bifurcation of the lower aorta was
performed at the hospital. The resected segment of the large vessel
was replaced by a homograft. It was the first operation of this type
to be performed in this part of the country.

THE BUFFALO PHYSICIAN

When the hospital opened in 1950 there was no space pro­
vided for a surgical research laboratory. Dr. Chardack accepted an
invitation from the late Dr. John R. Paine to start experimental
work in the old "firehouse laboratory" at the Buffalo General Hos­
pital. Three years later, in 1953, Drs. Chardack and Gage established
the first surgical laboratory at the VA Hospital. Recalled Dr. Char­
dack, "it was located in small, improvised quarters that were orig­
inally part of the hospital laundry." Since that time the hospital's
surgical laboratory and general research facilities have greatly ex­
panded and now serve an increasing number of investigators based
there and at the Medical School.
Early experimental work at the hospital was concerned with
the measurement of coronary flow, a standardized experimental
model of coronary obstruction, and an experimental evaluation of
surgical procedures for the relief of coronary arterial disease. They
were forerunners of the now widely-practiced modern operations
for this disorder.
Experimental work on a self-contained and implantable pace­
maker to correct complete heart block began in 1958 by the two
investigators in cooperation with Wilson Greatbatch, an electronics
engineer and assistant professor of electrical engineering at the Uni­
versity of Buffalo.
Its clinical implantation was performed and reported by the
team two years later, in 1960. The first longterm success with this
operation led to its immediate acceptance throughout the world as

Dr. Chardack

CONNECTORS

FUEL CAPSULE

THERMOPILE
DC/DC C0NVERT0R
CIRCUITRY
HERMETICALLY
SEALED CASE
PULSE GENERATOR
DEMAND CIRCUITRY

I S 0 T 0 P I C POWER SUPPLY

Cross-sectional diagram ol
the nuclear-powered unit.

One of the most recent electric pulse generators with conventional batteries.

The first two patients, Anthony /. Tasca and
Robert L. Peck, to receive nuclear pace­
makers in this country.

the treatment of choice for this condition, which carried a 50 per
cent mortality within a year after diagnosis and until then was un­
beatable by other means.
Well over 100,000 patients have now been treated by such
devices as well as pacemaker systems of increasing sophistication.
And the surgical group at the VA Hospital have been prominently
associated with many of the new techniques developed over the
sixties. The latest, the plutonium-fueled pulse generator perfected
by a French engineer/physician team and an American pacemaker
manufacturer, uses circuitry and electrodes developed from the
original design concepts of the Buffalo team.
There are a number of related fields also covered by the VA
Hospital's surgical service investigators. They are paired pulse
stimulation of the heart and studies on ventricular fibrillation re­
ported on in cooperation with the hospital's chief of cardiology
Dr. David C. Dean and Japan's Dr. Hiroshi Ishikawa.
But, said Dr. Chardack, the laboratory has also made contribu­
tions to other fields. "Experimental and clinical applications of
synthetic substitutes for skin used in treating third-degree burns
were reported on in the sixties. And the introduction of cryosurgery
by Dr. Maurice J. Gonder for treatment of prostatic obstruction and
of cryosurgery for cancer in general by Dr. Gage have also received
international attention and recognition."•

4

THE BUFFALO PHYSICIAN

A total of 22 alumni, wives, and guests attended the American
Medical Association Convention alumni reception at the St. Francis
Hotel, San Francisco on June 19. Mr. David Michael, director of
medical alumni affairs, hosted the reception.

Two Alumni
Receptions

Those attending were: Doctors Richard and Mrs. Ament, M'42,
Buffalo; E. R. and Mrs. Auden, Minnesota, guests; William and Mrs.
Ball, M'37, Warren, Pennsylvania; Charles Bauda, M'42, Buffalo;
Philomena Bauda, M'42, Buffalo; Ron Friedman, M'68, Santa Monica,
California; Fred and Mrs. Goldstein, M'56, 1000 Oaks, California;
H. W. Hale, Jr., Phoenix, guest; Annabel Miller Irons, M'46, La Can­
ada, California; Don LaPlatner, M'60, St. Petersburg, Florida; William
P. and Mrs. Magenheimer, M'44, Waterloo, New York; Joel and Mrs.
Paull, M'71, Buffalo; Sam Sanes, M'30, Buffalo; Miss Mildred
Spencer, Buffalo, guest; Barry and Mrs. Weinstein, M'69, Rochester,
New York.
Mr. Michael also hosted the American College of Surgeons
alumni reception held in October in San Francisco at the Hotel
St. Francis. There were 72 alumni, faculty, wives and guests attend­
ing. Doctors Richard Albert, Los Angeles (guest); Roland and Mrs.
Anthone, M'50, Buffalo; John and Mrs. Ambrusko, M'37, Buffalo;
Joseph G. Antkowiak, M'60, Pittsburgh; Robert M. Barone, M'66,
Buffalo; Delmer E. Batcheller III, M'51, Canandaigua, New York;
Charles and Mrs. Becker, M'38, Buffalo; Willard and Mrs. Bernhoft,
M'35, Buffalo; Herbert Berwald, M'27, Napa, California; William and
Mrs. BlaisdelI, M'59, Albuquerque; David A. Bloom, M'71, Los
Angeles; Mr. Ronald Brown, Los Angeles (guest); Richard J. Buckley,
M'43, Buffalo; Joseph S. Calabrese, Buffalo (faculty); Thomas Cummiskey, M'58, Buffalo; Donald DeLeutis, M'59, San Francisco; Joseph
M. Dziob, Buffalo (faculty); Jack C. Fisher, M'62, Charlottesville,
Virginia; Vincent P. Frantz, M'64, Houston, Texas; Ronald F. Garvey,
M'53, Dallas, Texas; Michael and Mrs. Gianturco, M'55, Buffalo; John
G. Gleichauf, M'62, Sante Fe, N.M.; Francis Hammond, Los Angeles
(guest); Glenn C. and Mrs. Hatch, M'28, Penn Yan, New York; Robert
C. and Mrs. Hatch, M'61, Modesta, California; David B. and Emma
Harrod (both faculty), Buffalo; William C. Hernquist, M'44, Wichita
Falls, Texas; John and Mrs. Ingall, Buffalo (faculty); Wendy Jacobson,
San Francisco (guest); Byron H. Johnson, M'45, Fresno, California;
Harris H. Kanel, M'57, Riverside, California; Marvin and Mrs. Kurlan,
M'64, Allentown, Pa.; Charles and Mrs. Leone, M'29, Erie, Pa.; Karl
Manders, M'50, Indianapolis, Ind.; Randolph J. and Mrs. McConnie,
M'43, Santurce, P. R.; J. P. and Mrs. Nesselrop, San Francisco (guests);
Eustace Phillies, M'38, Buffalo; E. and Mrs. Pollack, California (for­
mer E. J. Meyer resident); Albertus W. Rappole, M'37, Virgin Islands;
Bert W. and Mrs. Rappole, M'66, Tucson, Arizona; Vea J. and Henry
Riegler, Temple, Texas (guests); Bernard and Mrs. Shapiro, M'57,
Ansonia, Conn.; Carrol J. Shaver, M'44, Elma, New York; Russell
C. Spoto, M'59, Thousand Oaks, Calif.; William J. Staubitz, M'42,
Buffalo; Mr. James Stephens, University of Western Ontario (guest);
Samuel A. Weissman, M'69, Rochester, New York; Robert H.
Wilbee, M'59, Las Cruces, New Mexico; Charles Wiles and Jane
Wiles (both M'45), Buffalo; Jean D. Williams, M'68, Buffalo; Richard
W. Williams, M'64, Buffalo; Donald Yacht, M'59, Palo Alto, Cali­
fornia.•
WINTER, 1972

5

Dr. M. Luther Musselman is the
new chairman of the admissions
committee at the Medical School.
The 1937 Medical School graduate
has been on the faculty since'
1947. He was in military service
in 1943-44. He is a clinical asso­
ciate professor of medicine and
assistant director of the University
Health Service.

Prognosis from New SLE Test

Drs. Reichlin, Mattioli

Predicting which patients with systemic lupus erythematosis (SLE)
will have a low probability of developing renal complications is now
underway at the Veteran's Hospital. It is through a test involving a
precipitin reaction in gel with serum from the patient (Ouchterlony
Test) by Drs. Morris Reichlin (professor of medicine and research
professor of biochemistry) and Martha Mattioli (research instructor
in medicine) to identify an antibody to a nuclear RNA protein.
Said Dr. Reichlin, "if precipitating antibodies to RNA protein
antigen are present, it is a good prognostic sign. For the patient will
rarely develop kidney disease." He pointed out that response to
treatment for this group of patients is very good. "Many will improve
spontaneously without specific medication," he said. "Therefore
unless indications are strong, treatment should not be aggressive."
Other correlations made by the investigators reveal that patients
who make anti-RNA protein antibodies rarely possessed antibodies
to DNA (complement-fixing antibodies to ssDNA). "The presence
of the latter correlates well with the presence of renal disease," Dr.
Mattioli said.
This test has important predictive significance for in large
groups of lupus patients a little more than half (60%) will get kidney
disease, a leading cause of death. Said Dr. Reichlin, "the symptoms
may disappear but the blood test remains the same. Antibodies to
the RNA protein tend not to fluctuate and are present whether the
patient is ill or well. While the cause of this disease is unknown or
why patients make either antibodies to DNA or antiRNAprotein, we
have accomplished something empirical which is useful."
In the past, the only specific laboratory test for the diagnosis of
SLE has been antibodies to DNA, long known to be quite specific for
SLE patients. Antibodies to RNA protein seem also to be quite
specific for these patients while patients with other connective
tissue disease (such as rheumatoid arthritis) do not make antibodies
to the RNA protein. "Our test," Dr. Reichlin said, "represents a
further refinement in establishing prognosis and diagnosis in SLE."
Over a five-year period the investigators have been performing
this test and have found 39 positive cases (for antiRNAprotein) out
of a total 130 SLE cases. While patients with this anti-RNA protein
do have a more favorable prognosis, the answers to why there are so
many immunologic reactions or the pathogenic mechanism of many
of the clinical findings remain obscure. Concluded Dr. Reichlin
"it is hoped that the correlation of specific immunologic reactions
to specific clinical events will lead to a greater understanding of the
disease."•
6

THE BUFFALO PHYSICIAN

Dr. Ehsan Afshani, assistant professor of pediatrics and
radiology, with his new equipment.

Dr. fames R. Markello, assistant pro­
fessor of pediatrics, with a young
patient.

The basement and the first two floors of the new Children's Hospital
$15 million out-patient and research building are functioning. This
part of the building includes a new emergency-room, acute disease
clinics and an observation unit on the first floor. And eventually all
34 of the out-patient clinics will be located in the new building.
The radiology department is occupying more than two-thirds of
the second floor and the intensive care unit has been expanded
from 12 to 18 beds.
Three other clinics — surgery, eye and orthoptics — have been
completed. Also in operation is an expanded X-ray department,
pharmacy, administrative offices, admissions, chapel, gift shop and
front lobby. The other four floors will be completed during the
next several months.
The bright, cheerful building is decorated with great splashes of
red, yellow, blue with purple and orange accents.Q
WINTER, 1972

7

Thank you, Mrs. Lyle; ladies and gentlemen.
I am here today as a surrogate for many persons:
—for the two women of this community who in 1892 founded
The Children's Hospital;
—for all those women who in subsequent years have demon­
strated the continuity of concern that has provided basic support
for the progress of this hospital;
—for the physicians who have practiced here and have been
primary shapers, not just of the hospital, but of the whole field of
pediatric medicine;
-for those nurses and other health specialists whose care and
commitment have characterized and been essential to the hospital's
development;
President Ketter speaking at the dedication

-for the administrators and their staffs whose first allegiance
has not been to bureaucracy but to a vision of expanded achieve­
ment;
—for the many women who have been patients in this the only
children's hospital in the United States and Canada which has an
obstetrical division;
—for the infants and children whose fear and pain have been
alleviated here, or who have been helped to cope with what they
do not comprehend;
and finally, I stand here as a surrogate

A Hospital
University
Partnership
by
President Robert L. Ketter

-for the University faculty and students in the Health Sciences
who have been an integral part of the hospital since 1926, when
pediatric instruction was first offered here to students in our
School of Medicine.
From this tentative beginning forty-six years ago, the relation­
ship between the University and The Children's Hospital has
emerged as one which strengthens both institutions. Today, as we
dedicate this new out-patient and research building, the prospects
are favorable for a continued strengthening of the partnership.
For some years, the University has shared in the compensation
of the hospital-based faculty member; never before has it assumed
any responsibility for monetary compensation to the hospital for
space that is utilized for academic purposes.
This aspect of the partnership has changed.

In his address at the Children's
Hospital dedication ceremonies
President Ketter announced that
he had signed a letter of intent to
lease 45,000 square feet of space
from the hospital. The annual rent­
al would amount to approximately
$500,000. Each of the five schools
in the Health Sciences — dentistry,
health related professions, medi­
cine, nursing, pharmacy — will be
using some of the new classroom
and research space, Dr. Ketter said.

I have today signed and officially transmitted a Letter of Intent
for the University to lease space over and above what it now uses
in its academic programs at the hospital. Although the letter is
addressed to Mrs. Lyle, the President of the Board of Directors of
the Hospital, I do not believe it is inappropriate to read to you one
sentence of its contents on such an auspicious occasion:
"It is the purpose of this letter to indicate the intention of the
State University of New York at Buffalo to enter into further
agreements with The Children's Hospital of Buffalo to lease
approximately 45,000 net square feet of University dedicated
space within the Hospital specifically designed and con­
structed to meet the unique educational requirements of the
University which, because of its proximity and access to the
clinical programs of Children's Hospital, has particular educa­
tional and teaching significance."
8

THE BUFFALO PHYSICIAN

I should note that the contractual arrangement in question should
result in the realization by the Hospital of approximately $500,000
per year.
This letter adds a new dimension to the legal relationship of
affiliation between The Children's Hospital and the University. The
hospital undoubtedly will experience some degree of budgetary
relief. The University's Faculty of Health Sciences, with each of its
schools using hospital facilities, will benefit greatly from the availa­
bility of new classroom and research space. This is especially true
in view of the University's decision not to build a teaching hospital
on its Amherst or Main Street Campuses.
In the years ahead, the strengthened relationship between the
University and the hospital should generate even more of the
medical advances which have brought both national and interna­
tional attention to this community institution. Highlights of this
progress include the unique development of a total program of
"maternal and child health" — a program which now seems likely
to undergo additional growth with the appointment of our new
Chairman in the Department of Gynecology-Obstetrics.
The first open heart surgery in the United States for the trans­
position of the great vessels on infants was performed here in this
hospital. The hospital continues to be noted for its achievements in
cardiovascular surgery; and its treatment of heart ailments has
attracted children from great distances, even from foreign countrres.
Significant contributions have been made here to the work
that has been done in polio and epilepsy.
Research conducted at Children's has uncovered new knowl­
edge for the improved treatment of kidney ailments in children.
The "Guthrie Test" for the detection of PKU was developed
here.
And the list could continue.
Research activity such as this is essential to providing im­
proved health care. So is the teaching function which the hospital
An interested audience

fulfills for our students in the Health Sciences. Together they con­
tribute to the quality of care available to the persons who use this
hospital; and it is the provision of this care which constitutes the
hospital's third function.
Not one of these purposes could be adequately served without
proper facilities. The dedication of this new building and the
impending contractual arrangement between the hospital and the
University go far toward assuring the continued availability of the
resources necessary for the hospital to fulfill its mission.
Fifty years ago, in 1922, the first out-patient department at
The Children s Hospital was established. The enormous increase
in this type of care is well known; and the demand seems likely to
g r o w , e s p e c i a l l y if w e a d o p t s o m e f o r m o f n a t i o n a l h e a l t h i n s u r a n c e .
Nowadays, more than 75,000 visits are made annually to the out­
patient units in this hospital, and the new building we dedicate
today provides the most modern facilities for these persons.
The primary beneficiaries of this accomplishment will be the
citizens of Buffalo and Western New York, who constitute the bulk
of the hospital's out-patients. Therefore, the building symbolizes
for me the community service which has been a hallmark of the
hospital since its founding.
Yet the hospital has been more than a community servant. In
many respects, it has been a community venture. For instance, the
importance of community-based volunteer groups to the hospital
is well documented. The Tanner Building at the east end of this
new construction was the result of a community financed effort.
But perhaps the most dramatic illustration of the hospitalcommunity interdependence occurred in 1944, when Western New
York experienced a devastating polio epidemic. More than fourfifths of the hospital's existing beds for children were given over
to polio victims. For other illnesses, only patients in need of
emergency treatment were admitted.

The main lobby

Eventually, 706 positive diagnoses of polio were made and the
patients hospitalized at Children's. Hundreds of others were exam­
ined and released. Every available space in the hospital was filled,
including living rooms and conference and classrooms.
The problems of what to do with the many children who
needed extended care was solved when a prominent family made
available a large indoor tennis court which was transformed into a
temporary hospital annex. This was typical of the community sup­
port during those months of crisis.
Volunteers came to serve meals and wash dishes; business
executives came nightly to clean; entertainers came to perform.
The Department of Education brought school to the annex; the
Fire Department brought hospital-prepared meals through the snow
on fire trucks; the scouts brought scouting.
The community and hospital response to the crisis was total;
and I believe the spirit still exists for such cooperation and service.
This building certainly is an affirmation of it.
Therefore, the dedication we make today should be to the
continuation of the service The Children's Hospital has long pro­
vided to this community; t o the service it has rendered through its
provision of health care and its teaching and research. Most im­
portant, we should make our dedication to the children who will
benefit from this new building and the activities which will occur
here.
Isadora Duncan once wrote that "so long as little children are
allowed to suffer, there is no true love in this world." Today, the
University at Buffalo looks forward to a long relationship with The
Children's Hospital and its efforts to show that such love can indeed
exist.D
WINTER, 1972

11

Drug Abuse
Plateau

i

One of the nation's leading drug experts warned physicians to be
on the lookout for some of the "bizarre complications" that are
being reported as a result of use of inadequately sterilized needles
of heroin addicts. "One of these is the fatal invasion of the valves
of the heart by an organism known as pseudomonas and another is
meningitis caused by fungi," Dr. Donald B. Louria said. He is pro­
fessor and chairman of the department of preventive medicine and
community health, College of Medicine and Dentistry of New
Jersey, Newark. Dr. Louria spoke at the 52nd annual Trends in
Internal Medicine program of Continuing Medical Education.
The author of "The Drug Scene" and "Overcoming Drugs" also
predicted much more malaria among drug users in the next several
months. But he believes drug abuse has reached a plateau in
America and is on the wane. This is what most of the current
studies tell us.
The physician believes such programs as "TIP—Turn in a Pusher"
is wrong. "It is absolute disaster to have 100 or so 'square type
kids' spying on one another in our schools. Introducing this hate
technique is bad. You can't introduce hate and keep it only to the
pusher."
Dr. Louria went on to say that it is important to control the
supplies that come into this country. "This is a societal problem
and society must do something to make young people feel happy
and wanted. Such unhappy and alienated students will only become
more alienated by such programs as 'TIP'. Statistics show that the
more alienated the student, the more apt he is to smoke marijuana
frequently and to seek greater relief from more powerful agents.
The pusher who sells him the marijuana may introduce him to
other drugs or his companion may do so."
"We must offer young people alternatives — playgrounds,
athletics, work—to drugs. We must motivate people to get off drugs
and be productive, successful citizens. Leisure time and boredom
play right into the hands of the pushers."
Dr. Louria told the symposium that studies indicate that the
more frequently a student uses marijuana, the more likely he is to
use other drugs. "If he smokes marijuana only occasionally his
chances of going on to other drugs is only one out of five. If he
uses marijuana more than twice a week, this increases to one out of
two, and if he smokes it at least once a day, his chances of becom­
ing involved with other drugs rises to three out of four."
Studies of 20,000 reasonably affluent high school and junior
high school students in Northern New Jersey indicate that approxi­
mately 35 per cent used marijuana at least once, but only 15 per cent
use it regularly, the physician said. "Five to eight per cent of the
students use LSD and about the same number take speed and
heroin intravenously. One of the alarming factors is that four to
five per cent of the students in ninth grade are already on heroin
or cocaine. Use of cocaine, which can be taken by mouth, injection
or snuff, is increasing while the others have slowed down."
Dr. Louria believes that methadone is the best program to
combat heroin addiction but called for stronger controls to prevent
it from getting on the street.
12

THE BUFFALO PHYSICIAN

D r . L a w r e n c e J. N e m e t h , c l i n i c a l i n s t r u c t o r i n p e d i a t r i c s a n d
director of the adolescent drug program at Children's Hospital,
spoke about the Erie County program. " W e have treated about
200 patients in the inpatient and outpatient program last year, and
40 per cent were over 21 years of age. We had some problems
with the under 18-year-olds who didn't want their parents to know
they were on hard drugs. But generally our problems are not as
great as those of the New York City area."
Dr. Nemeth hopes there can be better co-ordination among the
80 Erie County agencies dealing in drug a b u s e . •

$5.5 Million to Roswell Park
Roswell Park Memorial Institute received the largest federal grant
($5,523,822) in its 75-year history to build a cancer cell center in the
block bounded by Ellicott, Carlton, Oak and Virginia streets. The
grant amounts to almost one-third of the total construction funds
set aside by the National Cancer Institute for the entire country.
The cell center will probably be completed in 1975, according to
Dr. Gerald P. Murphy, director of the institute. He is also a research
associate professor of surgery (urology) at the Medical School. Dr.
Murphy also received a one-year federal grant of $108,703 to help
develop a national prostatic cancer project.•

Child Psychiatry Director
D r . T h o m a s F. A n d e r s i s t h e n e w d i r e c t o r o f t h e d e p a r t m e n t o f
child psychiatry at Children's Hospital. He is also an associate pro­
fessor of psychiatry and pediatrics at the Medical School. Dr. Anders
has been at the Albert Einstein College of Medicine since 1967.
He has also been on the faculty of Columbia Psychoanalytic Clinic
and the Columbia University Nursing School.
Dr.. Anders received both his A.B. and M.D. degrees from Stan­
ford University in 1956 and 1960. He interned at Mount Sinai Hos­
pital, New York City. He was an assistant resident in pediatrics at
the Children's Hospital Medical Center, Boston (1961-62) and senior
resident in psychiatry, Columbia University College of Physicians
and Surgeons and the New York State Psychiatric Institute, New
York City.
The new director has been an assistant visiting physician at
Morrisania Hospital; an assistant and adjunct attending psychiatrist
at Montefiore Hospital and Medical Center; and senior investigator
a t t h e R o s e F. K e n n e d y C e n t e r f o r M e n t a l R e t a r d a t i o n a n d H u m a n
Development, Albert Einstein College of Medicine. He holds a cer­
tificate in psychoanalysis from Columbia and was certified by the
American Board of Psychiatry and Neurology in 1970. He has written
several papers on the newborn.•
WINTER, 1972

13

Lawrence Millhofer, a second-year
medical student, visits with head
nurse (2nd floor) Mrs. Antoinette McCuire and Mrs. Dorothy Fuller, LMP,
at the Wyoming County Hospital,
Warsaw.

An Upstate (Syracuse) Medical student,
Leo Scarpino (white jacket) and a
fourth-year UB physical therapy stu­
dent, Philip Morris, visit with a patient
at the Jamestown W.C.A. Hospital.

Miss Judith Stoyell, a fourth-year nurs­
ing student, and Mrs. Patricia Stopen,
director of public health nursing, Wy­
oming County. Judith hopes to go into
Public Health Nursing after graduation.

THE BUFFALO PHYSICIAN

Rural Health Care
"It was a fantastic summer experience in rural health care." That
was the consensus of 34 Health Sciences students who participated
in the third annual eight-week summer externship program in
Western New York. The students in the Schools of Medicine, Den­
tistry, Pharmacy, Nursing, and Health Related Professions partici­
pated in the program. They were almost unanimous in their praise
for their preceptors and how they went out of their way to help
them get involved in community activities and affairs. The students
liked the direct patient contact and they loved the rural living and
the friendly environment. They were well accepted by the health
professionals and the patients in the communities where they
worked and lived for two months.
One future physician said, "almost all the patients accepted me
as a doctor and discussed their problems and ailments quite frankly.
I was accepted well by the doctors, nurses, and other hospital per­
sonnel. In fact, any limitations placed on my activities were selfimposed. Areas where I lacked knowledge, I would let the doctor
take over."
Mark Twichell, a dental student said, "I got a better idea of rural
health care and the local people liked the idea of a student being in
the dental office."
Lynn Piersall, a medical technology student said, "It was an
invaluable experience. I learned many skills that I could only learn
through a concentrated clinical practice."
John Frischholz, a pharmacy student said, "It was a stimulating
experience for me. Many of my unanswered questions were an­
swered."
Richard Walcott, a medical student said, "I only wish the ex­
perience could have been 12 weeks or longer."
Linda Fremming, a nursing student said, "I had the opportunity
to observe, participate and learn about medicine and to see the
patient and his problems."
Other general student comments: "Most people as patients
seemed happy to help 'young doctors' by reviewing their signs and
symptoms; the people of both the hospital and town accepted me
and it resulted in several new friendships; medical practice was quite
sophisticated and very excellent; initially I held a stereotyped view
of rural medicine as being inferior to or behind that of larger city
hospitals. I have found this to be completely false. I discovered
that small doesn't necessarily mean inferior, and rural should not
be equated with behind the times."
Robert Mohr, a medical student, outlined his experiences as
follows: the first week was an orientation of the W.C.A. Hospital
(Jamestown), its services and personnel; the second and third weeks
were in the office of Dr. Carl F. Hammerstrom where I received an
overview of the practice of an internist—helping with physical exam­
inations, blood tests, and taking histories; the fourth and fifth weeks
WINTER, 1972

15

Joe Dolce, fourth-year pharmacy stu­
dent, and Ray Hunt, chief pharmacist,
Brook Memorial Hospital, Dunkirk,
check an order.

Mark Twichell, a second-year dental
student observes as Dr. Robert Watson
of Gowanda examines Randy Agle's
teeth.

we observed surgery; the sixth week we viewed pediatrics with Dr.
Woodward; the seventh week was in maternity with Dr. Messinger;
and the eighth week with Dr. Sinatra in family practice.
"I spent my evenings in the emergency room where the phy­
sicians were extremely helpful. It was here that I had a chance to
try out my diagnostic skills. I also spent time in physical therapy,
speech and hearing, social service, with visiting nurses, dietary, coun­
ty health services and inhalation therapy. I saw all facets of medical
and health professions. All areas of the hospital were open to us
and we were able to communicate with the other students and
medical and hospital staff," Mohr said.
Listed below are the host preceptors, participating hospitals,
the 34 health sciences students (college listed if other than UB),
and their disciplines:

Marge Wilhelm, fourth-year physical
therapy student, and Dr. Wesley Sly,
head of the department of physical
therapy at Brook Memorial Hospital,
Dunkirk, adjusting the head traction
machine.

Jamestown, N. Y. - H. Gregory Thorsell, MD'57; George Lawn, PhT,
DM; Bert Klein, DPM (W.C.A. Hospital). Students — Robert
Mohr, medicine; Philip Morris, physical therapy; Leo Scarpino
(Upstate Medical Center-Syracuse) medicine; Steven Weinberg
(N. Y. College of Podiatric Medicine), podiatry.
Dunkirk, N. Y. — Ray Hunt, R.Ph; Edmund Tederous, MD'43; Ronald
Passaforo, MD; Wes Sly, PhT, DM (Brooks Memorial Hospital).
Students—Joseph Dolce, pharmacy; Nicholas Fuerst, medicine;
Margaret Wilhelm, physical therapy.
Olean, N. Y. — Rena Houghton, RN; Arthur L. Beck, MD'57; Anthony
Torre, PhT; Sister Mary Josephine, medical technologist; Donald
Jones, R.Ph (St. Francis Hospital). Students—Dorothy Ackerman,
nursing; Dave Lillie, medicine; Mary Opalinski, physical ther­
apy; Lynn Piersall, medical technology; Patti Witt, pharmacy
(University of Texas-Austin).

Two students, Bob Mohr, second year
UB medical student, and Steve Wein­
berg, New York College of Podiatry,
observe as a nurse takes a patient's
blood pressure at the Jamestown
W.C.A. Hospital.

Wellsville, N. Y. — Richard Green, R.Ph; Thomas Wick, PhT (Jones
Memorial Hospital). Students — Michael Kellick, pharmacy;
Deirdre Robinson, physical therapy.
Portville, N. Y. — Duncan Wormer, MD. Student — John Marra,
medicine.
Dansville, N. Y. — Victor Breen, MD'40; Calvin Waterbury, R.Ph;
Jean Goings, RN (Dansville Memorial Hospital). Students —
David Breen, medicine; Albert Campagna, pharmacy; Richard
Ferreras, medicine; Linda Fremming, nursing.
Salamanca, N. Y. — David Widger, MD (Salamanca District Hospital).
Student—Charles Natalizio, medicine.
Gowanda, N. Y. — Fred Occhino, DO; Robert Watson, DDS. Students
—Anibal Rivera (University of Puerto Rico), medicine; Mark
Twichell, dentistry.
Warsaw, N. Y. — Fred Heller, PhT; James MacCallum, MD'37; Patricia
Stopen, RN (Wyoming County Hospital). Students — Richard
Baumgardner, physical therapy; Lawrence Millhofer, medicine;
Judith Stoyell, nursing; Richard Wolcott, medicine.
Bradford, Pa. - Dorothy Ekas, RN; Lloyd Cannedy, PhD; Dorothy
Blacklock, social worker (Bradford Hospital). Students — Amy
Colella (University of Pittsburgh), nursing; David Klein (Mt.
Sinai Program Hospital Administration), hospital administration;
Bridget Robinson (Mt. Holyoke College), social work.
16

THE BUFFALO PHYSICIAN

Newfane, N. Y. — Lee Vermeulin, R.Ph; John Argue, MD'35 (Newfane-lnterCommunity Hospital). Students — John Frischholz,
pharmacy; B. Dale Magee (Upstate Medical Center-Syracuse),
medicine.
Lockport, N. Y. — Christine Dini, LPT (Mount View Hospital). Stu­
dents — Kurt Elander, physical therapy; Steve Cash, physical
therapy.
Rotating Dental Project - Donald Bissell, DDS. Student - Carol
Herzlinger, dentistry.D

Children's Hospital and the School of Medicine will co-operate in a
multi-faceted investigation of hereditary and environmental factors
that affect a baby in its mother's womb. The three-year study is
being done under a $500,000 grant from the National Institute for
Child Health and Human Development.
The principal investigator is Dr. Ronald G. Davidson, professor
of pediatrics and director of the Division of Human Genetics at
Children's Hospital. The goal of the project is to develop better
techniques for prenatal detection of defective infants in time to treat
them before birth, if possible, or to give a mother the option of
having an abortion and trying again for a normal baby.
Two research assistant professors of pediatrics, Drs. Mario
Rattazzi and Patrick Carmody, are providing biochemical data for
other researchers as well as information on a large group of in­
herited diseases which lead to degeneration of the nervous system
resulting in severe mental retardation and early death.
Seven other Medical School faculty members associated with
Children's Hospital are participating in the project and their areas
of research are:
—The effect of environmental factors that may cause birth de­
fects by altering heredity-controlling genes, Dr. Judith A. Brown, re­
search instructor in pediatrics and Dr. Anil B. Muhkerjee, research
assistant professor of pediatrics.
—Possible effects of drugs taken by women who may be preg­
nant but are still unaware of the pregnancy, Dr. Sumner Yaffe, pro­
fessor of pediatrics and co-investigators. They are working with
laboratory animal embryos and with volunteer human mothers.
—The potential role of viruses and other infectious agents for
the developing baby and ways to detect before birth the baby that
is damaged by such infection, a team headed by Dr. Pearay L. Ogra,
associate professor of pediatrics.
—The role of immunoglobulins and white blood cells in the de­
velopment of mechanisms for resistance to infections, Dr. Margaret
H. MacGillivray, associate professor of pediatrics.
—The ability of the developing embryo to produce hemo­
globin, Dr. Robin Bannerman, professor of medicine, and Dr. Martha
Kreimer-Birnbaum, research assistant professor of medicine and
biochemistry. They hope to learn more about the mechanisms of
normal blood development and abnormal development in diseases
such as sickle cell disease.D
WINTER, 1972

17

Detecting
Defective
Prenatals

A Better Test
Gonorrhea
Dr. Apicella in his lab at the Meyer Hospital

A better serologic test for gonorrhea may stem from the research
work of Dr. Michael A. Apicella in the unit of infectious disease,
Department of Medicine. Studies in this laboratory have resulted in
the isolation of the beta antigen of Neisseria gonorrhoeae from the
crude alkaline extracted endotoxin of this organism. Says Dr. Apicella
"studies of purified constituents from the cell wall of this organism
might help to eliminate cross reactivity with other bacterial antigens,
a major problem in serologic tests proposed for use in detection of
acute gonococcal infection today."
When the SUNY at Downstate graduate (1963) arrived in
Buffalo two years ago, he had already studied the isolation and
physicochemical properties of the capsular antigens in several sero­
types of Neisseria Meningitidis (while serving in the U. S. Air Force
as director of the infectious disease research laboratory at Lackland
Air Force Base). But, with the rise in venereal diseases and an
urgency for the practical application o^ research to medicine, his
laboratory added the study of gonococcal cell wall antigens for
ultimate use in serologic testing systems to its continuing work on
meningoccal antigens.
A Buswell Fellow, Dr. Apicella began to experiment with an
extract of the gonococcus previously described by Dr. Johann Maeland, a former Buswell Fellow in the Center for Immunology. From
this crude preparation, Dr. Apicella was able to isolate purified beta
antigen. The yield, extremely low, required approximately five
grams of dry organisms to produce eight to ten milligrams of anti­
gen. Immunochemical analysis indicated the antigen to be an acidic
glycoprotein free of gonococcal alpha antigen and common entero­
bacterial antigens.
Explained Dr. Apicella, "recent epidemiological studies indicate
that a large reservoir of asymptomatic individuals with acute gono­
coccal infection exist in our population. But, unlike Syphilis, little
is known about the effect of long-term gonococcal infection in these
individuals. However, they serve as a source for acute debilitating
infection in others, necessitating therapy with potentially allergenic
drugs and resulting in considerable loss of man and woman power.
In addition, the gonococcus potentially can invade the blood stream
of some infected individuals usually causing arthritis and, more rare­
ly and ominously, endocarditis. A serologic test, which could detect
acute gonococcal infection, is the only way to eliminate the asymp­
tomatic carrier and halt the recent spiral in gonococcal infection,
which has made this organism the causative agent in America's No. 1
reportable bacterial infection."•
18

THE BUFFALO PHYSICIAN

D r . W a y n e L. J o h n s o n h a s b e e n n a m e d p r o f e s s o r a n d c h a i r m a n o f
the department of gynecology-obstetrics at the Medical School. He
will also be chief of the gyn-ob service at Children's Hospital. He
comes to Buffalo from the Indiana University School of Medicine
where he has been a professor since 1969. He was also on the
attending staff of Coleman Hospital, Indiana University Medical
Center, and chairman of gyn-ob at Marion County General Hospital.
Dr. Johnson received his medical degree from the University of
Virginia School of Medicine in 1954. He interned at Cleveland
Metropolitan Hospital and took his residency at the University of
Virginia Hospital. He was a medical officer in the United States
Army for two years (1955-57), and was on the faculty at the Univer­
sity of Virginia and the University of Washington Medical Schools
after returning from the service.
In 1967 Dr. Johnson was a special consultant for Project Hope
in Peru and at Madigan Army Hospital, Tacoma, Wash, in 1968-69.
He has authored or co-authored 40 papers.
He is a Fellow in the American College of Obstetricians and
Gynecologists and a Diplomate in the American Board of Obstetrics
and Gynecologists. Dr. Johnson will assume his new duties in
January.D

Dr. Johnson Named
Gyn/Ob Chairman

mJi
Dr. Johnson

Chinese Medical Student
Hing Har Lo, a Chinese born American citizen, is a third year student
in the School of Medicine. She is o n e of approximately 400 Chinese
students at the University. Before coming to Buffalo she worked
for five years as a radiation physicist at the Massachusetts General
Hospital.
In May Hing Har Lo was awarded the Grace Le Gendre Fellow­
ship of $1,000 given by the New York State Federation of Business
Professional Women's Clubs. The Amherst BPW sponsored her.
Hing Har Lo received her bachelor's degree from Adelphi University,
Garden City, N. Y. and her master's from Cornell University, Ithaca.
She completed high school in Hong Kong. Her father was a repre­
sentative of General Electric in China. The family left for Hong Kong
on the last commercial flight out of Chung King several years ago.
She has two brothers and a sister in North America (California,
Florida, Vancouver, B.C., Canada).
Last summer Hing worked in research in immunology at the
University. She hopes to specialize in nuclear medicine. She is
proud of her U. S. citizenship and deems it a privilege to work and
study in this country.
"I am glad President Nixon visited China and I hope the two
countries are drawn closer together. Although I am opposed to
Communism, I always will have a feeling of love for the country
of my birth," she said.D
WINTER, 1972

19

Hing Har Lo

Students and faculty participate in a give-and-take session.

Two second-year medical students, Donna Hanlon and Patricia Hart, are awed
by the new revised manual. This manual is the "core" of the material that stu­
dents should know and be able to use.

New Teaching
Techniques in
Pharmacology

20

THE BUFFALO PHYSICIAN

Students will list their top three choices and
most are matched with their first choice.

T H E PHARMACOLOGY DEPARTMENT h a s
developed a new look based on variety, flexi­
bility, self-instruction and responsiveness to
student needs. New teaching techniques and a
newly revised manual are features of the basic
medical course to start in January for 130 sec­
ond-year students.
There will still be class lectures, but they
constitute only about one-half of the scheduled
class hours. Other learning opportunities in­
clude panel discussions, clinical conferences,
demonstrations, seminars, films, tapes, and spe­
cial topic sessions, said Dr. Cedric Smith, pro­
fessor and chairman of the pharmacology de­
partment. All lectures and panel discussions
will be taped and available for review by the
students.
"We will use problem and case-centered
learning more extensively. This will encourage
the utilization of knowledge as opposed to
memorization for facts only," Dr. Smith said.
" O u r basic goal will still be teaching stu­
dents the way drugs act and their rational use
in therapy."

"We will continue to prepare examinations
to assist students in their own assessment and
to help them identify areas of weakness. Stu­
dent input and discussion following each exam­
ination permits reinforcement of the material
as well as improvement in the quality of the
scoring. The examination, as well as student
evaluations, makes it possible for the staff to
continually improve the quality and effective­
ness of their instruction."
Of perhaps most significance is an informal
student group of 6-12 members chosen by the
student class to meet periodically with no more
than two staff members to discuss informally
any problems that either students or staff have.
These discussions have proven most fruitful to
both groups last year and serve, in large part,
to identify problems and to prevent bigger dif­
ficulties from arising.
"These innovations clearly indicate the dedi­
cation of the staff for the teaching process,"
commented Dr. Smith. "We all look to con-

Dr. Edson X. Albuquerque, professor of pharmacology, demons
strates the new tape recorder to second year medical students,
Jan Schwartz and William Hall, who is president of his class.

One of the new learning tools will be a
newly revised manual which will be a "core"
of substantive material that all students of
medicine should know and be able to use.
This includes an outline of essential material
as well as reference material and recommended
reading. There are also problems and questions
usually taken from medical case histories.
Students will also have special topic sessions
of two to three hours per week for five to
eight weeks in groups of 5 to 12. In this period
the students will have more than 14 options
that include laboratory demonstrations, clini­
cal rounds, seminars by the students, inde­
pendent library work, formal classes and clinics.
In these the students choose from a variety of
topics — such as neurochemical aspects of
p s y c h o t r o p i c d r u g a c t i o n , al c o h o l i s m , p h a r m a ­
cology in anesthesia, cancer chemotherapy,
drug regulations, pediatric or neo-natal phar­
macology, clinical pharmacology, digitalis and
heart function and behavioral pharmacology.
WINTER, 1972

21

Dr. Robert I. Mclsaac, professor of pharmacology, uses charts in his seminar sessions.

tinued improvements." He sees the most press­
ing challenges as:
(1) More flexibility in scheduling and greater
utilization of self-instructional and selfpaced programs for both "core" ma­
terial and special topic activities, with
the focus on problem and case-centered
learning.

(2) The introduction of rational drug man­
agement and clinical pharmacology so
that eventually two courses, one pri­
marily basic and one primarily clinical,
would be available.
(3) Facilities and services that respond rap­
idly and efficiently to faculty needs in
developing new educational programs.n

Continuing Medical Education
Eight Continuing Medical Education Conferences are tentatively
scheduled beginning in January and ending in June. For further
information contact Mr. Charles Hall, director of continuing medical
education, at 2211 Main Street or call (716) 831-5526. Other pro­
grams will probably be added.
January 4-May 31, Clinics in Physical Examination of the Heart
Patient and Arrhythmia Workshops (20 Thursday evenings); Feb­
ruary, Modern Concepts of Coronary Care; April 4-6, Pediatric
Endocrinology; April 6-7, Spring Clinical Days (sponsored by Medi­
cal Alumni Association); April 14-15, Anesthesiology; May 3, Post
Operative Infections (with WNY Chapter, American College of
Surgeons); May 16-18, Fetal and Neonatal Monitoring; June, Pedi­
atric Refresher Seminar.D
22

THE BUFFALO PHYSICIAN

Many people visited the basic science departments.

Dr. Om P. Bahl, professor of biochemistry,
explains some of his research.

Dr. lack Lippes, associate professor of Cyn/ob, talks about family
planning.

Community-University Day

It was a rainy Sunday afternoon, but 5,000
people came to the campus for the 2nd annual
Community-University Day (open house). The
Medical School did its share of "selling" the
University to the community. The Medical
School tested for Sickle Cell Anemia and had
an exhibit on the "Physiological Effects of
Transcendental Meditation." There were tours
of the Amherst Campus and some 80 displays
and exhibits (including moon rocks, movie­
making and computers). There were concerts
by several musical groups, art exhibits and
theater, as well as athletic events and demon­
strations. Others visited with President Ketter,
faculty members and students.
WINTER, 1972

23

Polluted Waters
Threaten World's
Protein Supply

Waters polluted by methyl mercury threaten the use of protein for
human and animal consumption. That's what a biochemical in­
vestigator and expert on water pollution at the University found
following a 290-day study on rainbow trout. Fed but a single dose
of methyl mercury, Dr. Edward Massaro calculated that it would
take the rainbow trout more than 1000 days to lose half of the pol­
lutant from their bodies. But, he warned, this would be true only if
they were never again placed in a mercury-polluted environment.
About half of the total original mercury dose is stored in the
skeletal muscles (the edible portion) of the fish (55 percent of its
weight). Seventy percent of the total mercury in the fish was found
in its muscle tissue at 100 days. Only nine percent of the initial dose
was lost by the fish during the last 190 days of the experiment.
Through isotopic labeling, the associate professor of bio­
chemistry determined to what tissues mercury is distributed in the
fish as well as how long it is retained. The blood, gills, spleen and
liver took up high concentrations of methyl mercury at the fastest
rate, one hour after feeding, reaching its maximum at seven days and
dropping by day 100 to a third of its original value.
However, uptake of mercury in the muscle, brain, and lens of
the eye proceeded at a much slower rate and these organs held the
pollutant the longest. While it took 60 days for muscle and 34 for
the brain to reach maximum levels, the lens continued to take up
mercury after 250 days. Perhaps, said Dr. Massaro, methyl mercury
is a precipitating factor for the cataracts found by Japanese investi­
gators in some fishes.

Dr. Massaro

What are the implications for man? With a greater demand for
protein as the population increases, an efficient way of removing
mercury from lake waters may have to be found. Levels were very
low in the brain of the fish — high concentrations would be lethal.
Underway is a project by Dr. Massaro on the effect of mercury on
the mammalian brain — learning and behavior. By introducing low
levels of mercury intraperitoneally, the investigators — a team of
biochemists and psychologists — observed rapid changes in brain
metabolism and behavior of the mouse as well as prolonged
mercury uptake in the brain.
What are the implications for learning and of behavior in
humans? Explained Dr. Massaro, "no one has looked at what effects
very low levels of different toxic elements have on living systems,
on behavior, etc. How much does it take to disrupt brain metab­
olism? What are the mechanisms that determine toxic material
storage in the human?"
Investigation currently underway on children intoxicated with
lead are encouraging but until sufficient experimentation with ex­
perimental animals is concluded we cannot have all of the answers,
he said. "Another area we would like to explore are the synergistic
effects of a variety of different toxic materials on the human."
Concluded Dr. Massaro, "pretty much the same kinds of things
are going on in other species of fish as well. We must get going on
the problem of water pollution and start working, in a serious way,
on its many ramifications/'D
24

THE BUFFALO PHYSICIAN

New International Journal
T h e first i s s u e o f a n e w i n t e r n a t i o n a l j o u r n a l d e v o t e d t o p r o m o t i n g ,
on a worldwide basis, the rapid dissemination of original work on
all aspects of immunology, has just been published. It is immuno­
logical Communications, founded by The Center for Immunology
of the School of Medicine. The six issues to be published each year
are of eminent value to immunologists, biochemists, microbiologists,
virologists, cell biologists, molecular biologists, pediatricians, sur­
geons, and those involved in internal medicine and cancer research.
Its e d i t o r i a l c o m m i t t e e o f f i v e f r o m t h e U n i v e r s i t y u n d e r c h a i r ­
m a n D r . N o e l R. R o s e ( p r o f e s s o r o f m i c r o b i o l o g y , a s s i s t a n t p r o f e s s o r
of medicine, and head, The Center for Immunology) are Dr. Pier
L. B i g a z z i , r e s e a r c h a s s o c i a t e p r o f e s s o r o f m i c r o b i o l o g y ; D r . S t a n l e y
Cohen, professor of pathology and acting head, The Center for
Immunology; Dr. Allan Grossberg, research professor of micro­
biology; Dr. Morris Reichlin, professor of medicine and research
p r o f e s s o r o f b i o c h e m i s t r y ; D r . C a r e l J. v a n O s s , p r o f e s s o r o f m i c r o ­
biology.
A n d its 2 9 - m e m b e r e d i t o r i a l a d v i s o r y b o a r d i n c l u d e s m o s t o f
the internationally renowned researchers in the field of immunology
f r o m t h e U . S., C a n a d a , E n g l a n d , F i n l a n d , A u s t r a l i a , T h e N e t h e r l a n d s ,
Israel, Czechoslovakia and Japan.•

Community Psychiatry Grant
The Division of Community Psychiatry at the University has been
awarded a $148,000 grant from the National Institute of Mental
Health to measure the quality of mental health services. The threeyear project, headed by Dr. Jack Zusman, director of the Division
and professor of psychiatry, has been supported for the past two
years through funds from the United Health Foundation of Western
New York, a United Fund agency.
According to Dr. Zusman, "millions of public and voluntary
dollars are spent annually in this community without any scien­
tifically v a l i d m e a n s o f a s s e s s i n g t h e q u a l i t y o r e f f e c t i v e n e s s o f t h e
(mental health) services supported by these funds. Spending mil­
lions of dollars on services and only pennies to evaluate these
s e r v i c e s is a f a l s e e c o n o m y a t b e s t . " T h e u l t i m a t e p u r p o s e o f t h e
r e s e a r c h is t o d e v e l o p t h e s c i e n t i f i c t o o l s t o e n a b l e a n a g e n c y t o
d e t e r m i n e t h e a d e q u a c y o f its s e r v i c e s a n d p i n p o i n t a r e a s w h i c h
need improvement^
WINTER, 1972

25

Dr. George Thorn,
Emeritus Professor

A. N

INTERNATIONALLY respected endocrinologist, Dr. George
Widmer Thorn is far more than a recognized expert on disturbances
of t h e adrenal gland. He is the e p i t o m e of t h e medical triad; a
teacher, clinician and researcher.
Born in Buffalo, New York, in 1906, he attended the College
of Wooster for two years and then entered the University of Buffalo
School of Medicine, receiving the M.D. degree in 1929. Lor six years
he remained at Buffalo, first as a house officer (1929-30) at the Mil­
lard Lillmore Hospital and then as an assistant in the dfepartment of
physiology and medicine. It was during this time that he collabor­
ated with Dr. frank A. Hartman in preparing a crude form of
adrenal-cortical extract used in the treatment of Addison's disease.
These compounds compensated for the body's lack of cortisone
and restored the natural sodium-potassium balance. Although
"cortin" did not cure Addison's disease, it arrested its progress so
that patients could again lead useful lives. In 1934 Dr. Thorn came to Harvard Medical School as a Rocke­
feller fellow in Medicine. Shortly thereafter (1936) he accepted an
associate professorship of medicine at Johns Hopkins School of
Medicine. He returned to Harvard in 1942 when he was appointed
to the oldest and most distinguished chair in American medicine
as Hersey Professor of the Theory and Practice of Physic. Simul­
taneously he became Physician-in-Chief at the Peter Bent Brigham
Hospital, positions he now holds. In 1968 Dr. Thorn, with his ap­
pointment as Samuel A. Levine Professor of Medicine, became the
occupant of two endowed chairs.
Dr. Thorn's research has concentrated on endocrinology and
metabolism. He pioneered in studies of salt and water metabolism,
the effects of high altitude on adrenal function, the myopathy of
thyroid disease, and he has made significant contributions in further­
ing medical knowledge of diabetes mellitus.

George Widmer Thorn,
M.D. Hersey Professor
of the Theory and Prac­
tice of Physic, and Sam­
uel A. Levine Professor
of Medicine, Harvard
Medical School and
Head of the Depart­
ment of Medicine at
the Peter Bent Brigham
Hospital; Physician-inChief, Peter Bent Brigham Hospital. On June
30, 1972 Dr. Thorn be­
came Emeritus Professor.•

But perhaps his greatest contribution is his research on corti­
sone and ACTH (adreno-corticotropic hormone) and the develop­
ment of its use in the treatment of numerous diseases. He was
among the first to show that complete adrenalectomy could be
performed in man, and he initiated the earliest work in human
kidney transplantation at the Peter Bent Brigham Hospital.
In 1946, Dr. Thorn was attracted to the possibility of making
an artificial kidney along the lines of that originally designed by
Dr. Kolff, who, shortly after the War, told o n e or two American
scientists about this development. Dr. Thorn immediately gathered
around him an able team to construct this kidney and by 1948 and
1949, Dr. Thorn's Department was the first in the United States to
have an active dialysis program for the treatment of renal failure.
Dr. Thorn used this not only to treat renal failure, but as a basis for
his later interest adrenalectomy for hypertension, in the patho­
physiology for advanced renal disease, and for his collaborative
work with the Department of Surgery in the initial trial of kidney
transplantation. This was done in 1951, and could not have occurred
without Dr. Thorn's interest in dialysis and his original and pioneer­
ing work in the use and construction of an artificial kidney.
26

THE BUFFALO PHYSICIAN

More recently Dr. Thorn has devoted a substantial portion of
his research and teaching interests to cardiovascular diseases. A
major aspect of his endeavors has been in the diagnosis and treat­
ment of patients with hypertension. Through his efforts, stand­
ardized procedures have been developed, particularly for those
patients with remediable hypertension due to adrenal gland overfunction and to kidney disease.
Dr. Thorn is a highly respected teacher, known for his lucid
presentations. His skill in the design, execution and interpretation
of clinical experiments has been transmitted to many generations
of Harvard Medical students who have gone throughout the world
to extend his teachings in diverse fields of scientific investigation
and clinical practice. His laboratory at the Brigham often has been
called "a medical U.N."
Dr. Thorn is one of the founding Editors of the medical text­
book "Principles of Internal Medicine" which has pioneered in new
technics of presenting medical material to students as well as to
practitioners. This textbook is now distributed on a world-wide
basis and regularly translated into several languages. He is also the
author of a monograph on Addison's Disease. He presently is on
the Advisory Board of the "American Journal of Medicine".
National and international awards bestowed upon Dr. Thorn
are numerous. He holds eight honorary degrees: Harvard (1942);
Dalhousie (1950); Temple (1951); Queens University, Ontario (1954);

Over 700 physicians trom Canada and the states attended a two-day immunodermatology Workshop in june.
During the conference, directed by professor of microbiology Ernst H. Beutner and his microbiology associates,
clinical assistant professors Clark Triftshauser and William Hale, and assistant professor Russell Nisengard, the regis­
trants — practicing dermatologists and internists — were exposed to reviews and demonstrations of current meth­
ods for immunopathologic studies of skin diseases and its relation to other diseases involving auto-aggression. There
were demonstrations of procedures for available diagnostic methods and a review of basic concepts to laboratory
findings.
Among the teaching faculty — all experts in the field — were microbiology chairman Felix Milgrom, Mayo Clin­
ic's Robert Jordon and Warsaw Academy of Medicine's Tadeusz Chorzelski. Co-sponsors of the two day con­
ference were the microbiology department, the Rochester Dermatology Society and the Eastwood Pharmacology
Company of Buffalo.O

Medical Society of the
State of New York
Cocktail Party
Hosted by:
SUNY at Buffalo
Medical Alumni Association
David K. Michael
Open to:
All Alumni and Friends
Monday, February 12, 1973
Royal Ballroom, B
Americana Hotel
New York City

Medical Alumni Association
1973 Spring Clinical Days
Statler Hilton Hotel
April 6 & 7
Guest Speaker: Leonard Wood­
cock, President UAW, speak­
ing on Universal Health In­
surance
Program will feature: Clinical
Pharmacology with emphasis
on drug reactions and inter­
actions as applied to all areas
of clinical practice.
1973 REUNION
CLASSES
April 6-1923
April 7-1928, 1933,
1938, 1943, 1948, 1953,
1958, 1963.
(details later)

Louvain University of Belgium (1960); Suffolk (1961); College of
Wooster (1963); and the University of Geneva, Switzerland (1965).
Among his honors are: the American Medical Association's Gold
Medal; Alvarenga Award; Gordon Wilson Medal of the American
Clinical and Climatological Association; John Philips Memorial
Award of the American College of Physicians; Modern Medicine
Award; the George Minot Award of the American Medical Associa­
tion; and the Julius Adams Stratton Prize for Cultural Achievement
from the Friends of Switzerland.
Dr. Thorn is a fellow of the American Academy of Arts and
Sciences, a member of the Executive Committee of the Corporation,
Massachusetts Institute of Technology, a member of the Association
of American Physicians (president, 1969-70), and a member of the
American Clinical and Climatological Association (president, 195859), American Physiological Society, American Society for Clinical
Investigation, Endocrine Society (president, 1963), Society for Ex­
perimental Biology and Medicine, Federation of American Societies
for Experimental Biology, the Royal College of Physicians (Great
Britain), the Royal Society of Medicine, the Royal Academy of
Medicine of Belgium, Commander in the Order of Hipolito of
Unanue, Peru, the Norwegian Medical Society and honorary mem­
ber of the Indian Society of Endocrinology. He is a Master of the
American College of Physicians, Consultant to National Medical
Care, Incorporated and Chairman of the Editorial Board of Medical
Communications, Incorporated. Dr. Thorn is also a member of the
Swedish Medical Society.
Dr. Thorn will continue his activities as Director of Medical Re­
search of the Howard Hughes Medical Institute; as an editor of the
PRINCIPLES OF INTERNAL MEDICINE; as a member of the Executive
Committee of the Corporation, Massachusetts Institute of Tech­
nology; and effective last July 1 he began his duties as Editor-inChief of the MEDCOM Faculty of Medicine.•

A Moral Issue
A 20-minute film—"Witch Hunt of a Doctor" — that deals with a
controversy over a moral issue at the Medical School in the 1850's
has been produced by the Lakes Area Regional Medical Program.
Co-operating in the venture was the Erie County Medical Society,
the Medical Society of Western New York and the Health Sciences
Faculty at the University.
The film tells the story of Dr. James Piatt White, professor of
obstetrics at the Medical School, bringing 22 medical students to a
basement to witness a birth by an unwed mother. This was the first
clinical observation by students in the United States. One member
of the community wrote some letters to a Buffalo newspaper noting
this practice by Dr. White as immoral and indecent. A court case
ensued. The film describes the court trial and the birth of the baby.Q
28

THE BUFFALO PHYSICIAN

Artist's drawing of planned
expansion at The Buffalo
General Hospital. New build­
ing, at left, would be 73 sto­
ries high instead of the 76
as shown, but could be ex­
panded to 76 stories at some
future date.

Construction is expected to start in the spring of 1974 for the
$75,800,000 expansion and modernization of the Buffalo General
Hospital. Hospital officials are seeking agency approval and funding.
A major feature of the building program will be incorporation of the
hospital's emergency and outpatient clinics into an ambulatory
services program that will provide continuous care for residents of
the neighborhood as well as others in the hospital referral area. This
will be in the basement of the new building.
The project includes:
—Expansion of the present Rudolf G. Hils Building from the cor­
ner of Ellicott and Goodrich Streets, horizontally to High Street and
vertically to 13 stories over-all. The existing building is just four
stories above ground.
—An increase of the hospital's inpatient bed capacity to 704
from 689. A total of 589 of the 704 beds would be located in the
Hils Building and the other 115 in the adjacent West Building,
opened in 1951.
—Demolition of the East Building, constructed in 1896, and
elimination of the large patient wards located there, one of which
has 27 beds.
—Modernization of the West Building, Clifton Memorial, the
first part of which was opened in 1917, and the South Building,
opened in 1933.
Non-conforming operating rooms will be eliminated and a new
suite of operating rooms opened on the second floor. New diag­
nostic X-ray facilities will be on the third floor. Outdated electrical
and ventilation systems will be revised. Office and laboratory space
will be expanded for related teaching, research and development
programs.
Rogers, Butler, Burgun and Bradbury of New York City, who
developed the hospital's long-range building program in 1964, are
the architects. Phase I was completed and put into operation in
November of 1969.•
WINTER, 1972

29

$75.8 Million
Expansion
For BGH

Allergic
Disease
Center

A husband and wife M.D. team, Atsuko and Tadao Okazaki, are working on histamine estima­
tion with Dr. Arbesman.

BUFFALO has

been added to the National Institute of Allergy and

Infectious Disease network of nine allergic disease centers.

One

of only two to be funded this year, it will be directed by Dr. Carl
E. Arbesman, clinical professor of medicine and microbiology who
heads the allergy research laboratory at both the Buffalo General
and Children's Hospitals.
Under a $57,470 grant (it will cover the first year of a three-year
The seven original Centers, estab­
lished in June 7977, are located at:
Robert B. Brigham Hospital, Bos­
ton; Johns Hopkins University, Bal­
timore; Washington University, St.
Louis; University of Wisconsin,
Madison; Scripps Clinic and Re­
search Foundation, La Jolla, Calif.;
and Children's Asthma Research
Institute and Hospital and National
Jewish Hospital and Research Cen­
ter, both in Denver, Colorado. In
July of J972 two new centers were
established at the University of
Michigan and Buffalo General Hospital.•

program) he will work with entomologists, biochemists and others
in the field to find better methods of protection for the vulnerable
from serious insect stings. From the venom of bees, wasps, hornets,
and yellow jackets — more deaths in this country due from these
than from poisonous snakes — the multidisciplinary team will try
to develop more specific and effective extracts for use in immuniza­
tion against such stings.
Said Dr. Arbesman who has contributed over 300 publications
to the literature as well as a new tool to study various immunological
factors involved in allergy — the anti E globulin, "reactions to sting­
ing insects may range from local swelling, disability for several days,
hives, difficulty in breathing, to serious anaphylactic shock and
death. It is this type of patient that we are most concerned about."

30

THE BUFFALO PHYSICIAN

Migration inhibition factor studies occupy the time of Drs. Lynne Burek and Konrad Wicher.

Drs. tynne Burek and Robert E. Reisman do cell sensitization.

Dr. Dorland Davis, director, National Institute of Allergy and Infectious Disease; Dr. Luz Froehlich, assistant for
clinical programs; Dr. Arbesman, Dr. Reisman, and Dr. William Cay, associate director of extra-mural program
for NIAID.

Allergic diseases, which affect over 31 million, take their toll
in disability rather than in deaths. And they are the principal cause
of disability for the "under 17" age group while the second or
third major cause for the "under 45" category.
Three National Institute of Allergy and Infectious Disease
officials toured the unique research and clinical allergic disease
facilities in Buffalo following award of the grant. Said its director
Dr. Dorland Davis, "there are tremendous components in Buffalo
for the new allergic disease center. The University itself is well
staffed with highly-trained immunologists, the hospitals have ex­
cellent clinicians with great skills and interests, and Roswell Park
is one of the leading institutions in medical science. We believe
that through this concentration of resources—both in terms of pro­
fessional effort and funds—we can accelerate the process by which
recent advances in immunology can be more effectively applied to
the care of the allergic patient."
Dr. Davis pointed to only four projects and $80,000 in grants
in 1955 as compared to 280 projects and $15 million in grants
today. In establishing these centers for allergy research he pointed
to the Institute goal of better diagnosis, prevention and treatment
of allergic diseases. "We hope that knowledge gained through
these centers will result in better care for those who suffer the
debilitating effects of allergy."D

Dr. John Wypych and Peggy Kayne examine the fraction collector.

Dr. Arbesman's multidisciplinary
team: Dr. Robert E. Reisman, clini­
cal associate professor in medicine,
pediatrics; Dr. Konrad Wicher, as­
sociate professor in microbiology
and research assistant professor in
medicine; Dr. John Wypych, re­
search instructor in microbiology
and research assistant instructor in
medicine; Dr. Willard K. Elliott,
professor in biochemistry; Dr.
Anthony Yurchak, research assis­
tant professor in medicine; Dr.
Tadao Okazaki, research assistant
instructor in medicine; Dr. Yosuke
Fujita, research assistant professor
in medicine; Dr. Allen Benton, as­
sociate professor in entomology;
and consultant Dr. Noel Rose, pro­
fessor of microbiology, assistant
professor of medicine and director
of The Center for Immunology_•

A $630,000 federal grant has been awarded the Lakes Area Regional
Medical Program by HEW to underwrite an emergency medical
s e r v i c e s s y s t e m i n Erie C o u n t y a n d a H e a l t h E d u c a t i o n C e n t e r i n
Erie, P e n n s y l v a n i a . D r . J o h n R. F. I n g a l l , d i r e c t o r o f L A R M P , s a i d
t h e s e f u n d s w i l l b e u s e d t h r o u g h A p r i l 3 0 , 1 9 7 3 . T h e Erie C o u n t y
Health Department will receive $250,000 and the Pennsylvania
center $325,000. The remaining $55,000 will underwrite administra­
tion of the two projects. Both grants may be renewed in subsequent
y e a r s if t h e p r o j e c t s p r o v e e f f e c t i v e .
The development of the Lakes Area Health Education Center
i n Erie, P e n n s y l v a n i a c a m e i n t o b e i n g a s a r e s u l t o f t h e 1 9 7 1 C a r n e g i e
Commission Report on Higher Education and the Nation's Health,
which proposed the establishment of 126 such centers in the United
S t a t e s . T h e p u r p o s e o f t h e s e c e n t e r s is t o p r o v i d e b a s i c a n d c o n ­
tinuing education programs locally for health care professionals,
which ultimately will improve the quality of health care delivered
in and around the surrounding areas of the center. The LAHEC
project has received some previous funding from the Veteran's
Administration in Washington and St. Vincent Hospital and Hamot
M e d i c a l C e n t e r o f Erie, P a . M i c h a e l C . J. C a r e y o f Erie is d i r e c t o r o f
t h e LAHEC p r o j e c t . D r . R o b e r t T. R e n z , o f Erie, s e r v e s a s p r e s i d e n t o f
LAHEC.
D r . I n g all a l s o a n n o u n c e d t h a t a n e m e r g e n c y m e d i c a l s e r v i c e s
system, designed to improve health care by establishing a functional
e m e r g e n c y m e d i c a l s e r v i c e s s y s t e m i n Erie C o u n t y a n d e v e n t u a l l y
to surrounding communities, will receive $250,000 from the new
grant to establish this service. The project was developed by the
Erie County Emergency Medical Care "Blue Ribbon" Committee,
w h i c h s e r v e s in a n a d v i s o r y c a p a c i t y t o Erie C o u n t y H e a l t h C o m ­
missioner Dr. William Mosher, and the Lakes Area Regional Medical
P r o g r a m . T h e s y s t e m is a r a d i o c o m m u n i c a t i o n s n e t w o r k w h i c h
will link persons concerned with emergency medical needs such as
individual crises to community-wide disasters. Radio equipment
will be phased in over a three-year period to hospitals, ambulances,
police and fire departments, fire base stations, transit authority, etc.,
for this use. The project also has an educational component where­
by over the next three years, some 5,000 ambulance and rescue
squad attendants will receive special training. The program, Medical
E m e r g e n c y T e c h n i c i a n (MET) is m a n d a t e d f o r c o m m e r c i a l a m b u l a n c e
attendants and strongly recommended for volunteers by New York
State.D

S630 000 Gf3.nt
'

Two grants have been awarded to a Buffalo microbiologist, Dr. Carel
J. v a n O s s . U n d e r t h e f i r s t , a $ 3 2 , 8 0 0 t h r e e y e a r N a t i o n a l I n s t i t u t e s
of Allergy and Infectious Diseases grant, the professor of microbi­
ology at the Medical School will continue studies on bacterial sur­
faces, virulence and complement sub-factors responsible for phago­
cytosis.
In the second grant, a three year $100,227 National Institute of
General Medicine grant, he will continue studies on separating
blood serum proteins by ultra-filtration.•

Microbiology
Grants

WINTER, 1972

33

tO

LARMP

New Approach to
Understanding
Hallucinogens

There is a new approach to understanding hallucinogens. It grew
out of an idea of Dr. Jerrold C. Winter's, an associate professor of
pharmacology, who felt that investigating stimulus properties of
these drugs might prove informative.
"As is true of many of my ideas," Dr. Winter said, "nothing
came of it until I was able to convince a graduate student that it
might be an interesting topic for a dissertation." The student, Dr.
Ira Hirschhorn (he is now at the Medical College of Virginia) ex­
amined the stimulus properties of Mescaline and LSD in rats for
two years, finished his thesis and, in Dr. Winter's words, "left me
with the sure knowledge that the major emphasis of my personal
research program would soon shift to the study of hallucinogens as
discriminative stimuli."
Explained Dr. Winter, "a traffic light may be thought of as a
discriminative stimulus. A feature of our environment, it has come
to control a part of our behavior as a result of our prior history of
training. If a color-blind investigator had to determine whether a
light was red or green he might put the problem to a number of
motorists in the guise of a traffic signal and observe their behavior.
"If a majority stopped upon encountering it he would conclude
that the light was red. But if most drove on by it the color had to
be green. Our investigator would thus obtain a nonverbal answer to
an unspoken question."
Similarly, continued the pharmacologist, by applying well-es­
tablished principles of behavior, communication can be established
with nonverbal species or, he explained, "we can in a limited but
very well-defined sense talk with the animals and they talk back."

Dr. Winter

In an experiment with rats, the stimuli are two colorless liquids
— one a salt solution and the other containing a hallucinogen such
as Mescaline — not red or green lights. Following injection of the
drug, some of the lever-press responses made by the animal are
reinforced by delivery of food. However, following treatment with
saline, no responses are reinforced. They may be punished by de­
livery of a mild electric shock.
A pattern of responding soon emerges. On days when mesca­
line is given, bar presses occur at a high rate. When saline is the
treatment, response is almost nil. Said Dr. Winter "if we have been
careful to rule out all other features of the animal's environment
as possible cues, even in this simple experiment we have established
a discrimination. Without words we have been told by the rat that
it can tell the difference between saline and mescaline."
In actual practice while many animals are used in precisely de­
fined experimental designs the principles remain the same. Not only
can questions be asked about hallucinogens (as well as closelyrelated nonhallucinogenic drugs) but, as Dr. Winter said, "we can
also begin to apply the techniques of neurochemistry and neuro­
pharmacology to the analysis of a behavioral phenomenon. Whether
we will learn more about behavior or about hallucinogens is a moot
question."
A practical application of this investigator's work is the evalu­
ation of new drugs for hallucinogenic activity before they are used
in man by comparison with known hallucinogens. Whatever im34

THE BUFFALO PHYSICIAN

portance the abuse of hallucinogens may have, Dr. Winter believes
that "it is insignificant when compared with the potential good to
be derived from an understanding on the mechanism of action of
hallucinogens and the light such understanding may shed on the
biological bases of mental illness."
Following training as an organic chemist at the University of
Rochester Dr. Winter served in the U. S. Navy for three years (he
now spends one night a week teaching oceanography to fellow
Naval officers). Upon release from active duty in 1962 he came to
the University to earn a PhD in pharmacology (1966) and after post­
doctoral training at the University of Rochester Medical School, was
invited to return to the University as a faculty member.D

New Dermatology Chairman
Dr. Richard L. Dobson has been named professor and chairman of
the department of dermatology at the School of Medicine at Buf­
falo. He assumed his new duties June 1. He comes to Buffalo from
the University of Oregon Medical School, Portland, where he has
been an associate professor and professor of dermatology since
1961. He was also a senior scientist at the Oregon Regional Primate
Research Center from 1964 to 1968. Dr. Dobson served on the
University of North Carolina Medical School faculty from 1957 to
1961. During the 1969-70 year he was on sabbatical as a visiting pro­
fessor of physiology, Catholic University, Nijmegen, The Nether­
lands.
Dr. Dobson was born in Boston, did his undergraduate work
at the University of New Hampshire in Durham, and received his
M.D. in 1953 from the University of Chicago School of Medicine.
He interned at the Cincinnati General Hospital (Ohio) in 1953-54.
He was a Fellow in dermatology at the Dartmouth Medical School,
Hanover, New Hampshire from 1954 to 1956. Dr. Dobson was a
Public Health Service Research Fellow of the National Institutes of
Health in 1956 and an assistant in dermatology at the Hitchcock
Clinic, Hanover, N. H. in 1957.
Dr. Dobson has been active in several national and international
professional organizations in dermatology and physiology. He has
addressed international groups in Japan, Switzerland and Washing­
ton, D. C. Dr. Dobson has authored or co-authored 100 articles for
professional publications. He is a Fellow of the American Associa­
tion for the Advancement of Science, the American College of
Clinical Pharmacology and Chemotherapy and the American College
of Physicians. He is listed in Who's Who and American Men of
Science.O
WINTER, 1972

35

Dr. Dobson

'

-9

The 1976 Class at Orientation
It was a new world for the 135 new medical students (15 more than
last year) who arrived on campus early for two days of orientation.
There were many "welcomes" — one by Dr. Albert Somit, executive
vice president of the University who promised "some significant
changes here in the four years before you." As the Main Street
campus is vacated he expects to see Health Sciences expand until
"about the time you graduate most of this campus as you now see
it will be a Health Sciences campus." He also pointed to an entirely
different educational program four years hence that is as yet undefinable and perhaps a profound change in the medical profession
where "in the doctor's role house calls may be reinstituted."

WINTER

1972

From Vice President of Health Sciences and acting dean of
medicine Dr. Clyde Randall, a tribute for the promise shown by
each one who sits in this freshman class as well as a reminder of
the 30 who apparently did not make it for your place. There was
also an assurance that a new vice president for health sciences and
a dean of medicine is expected within the next year.
"You are a unique class," he continued. "For you reflect the
new role of the female in medicine as well as in all aspects of our
lives (about one fourth of this class are women)." But he admonished
that the variety of possibilities offered by medicine leave no
reason to feel stifled or handicapped at any time.
And there were rap sessions with sophomores about what
courses to take, how to study, etc., a picnic supper and reception
to meet faculty. There were also registration, pictures, tours, ad­
vanced placement tests for some and finding a place to live for
others. It was a busy, frustrating experience, but everyone adjusted.
Dr. M. Luther Musselman, chairman of admissions, said his com­
mittee conducted over 600 personal interviews. "These were se­
lected from the 4,244 applications. There are 36 women in the class
and several more minority students than last year. They all come
from New York State except 14. Eight of the 14 come from seven
states — California, Florida, Mississippi, North Carolina, Ohio, Penn­
sylvania, and Washington, while six others come from the West
Indies and Africa. Most of the new students are science majors, but
a few majored in German, History, Philosophy, English, French,
Anthropology, Engineering, Political Economics and American
Studies. The students come from 68 undergraduate colleges and
universities."
The Class of 1976 did some diagnosing during orientation. Pa­
tient A, a 39-year old former construction worker, was a heavy
drinker. He exhibited nausea, vomited, had diarrhea as well as four
major epileptic episodes. Could they, as freshmen on their second
day of orientation, make a diagnosis?
They did. It was acute alcoholism, the greatest drug abuse of
our times. It had completely disrupted Patient A's life, now di­
vorced, unable to continue in construction work, self-employed
when possible. Program moderator Dr. Joseph Aquilina told the
freshmen that the patient who started to drink as a teenager slowly
built up a tolerance to alcohol.
When the second patient, a master electrician by trade, com­
plained of weight loss, bloody stools and anemia, the question was
raised as to whether he drank or smoked. No, his last drink was
taken two years ago. Yes, he did smoke a pack a day. A bleeding
peptic ulcer was diagnosed for Patient B whose history of ulcers
started back in 1949.•
38

THE BUFFALO PHYSICIAN

The Family Practice Center at Deaconess Hospital received a
$108,000 federal grant to triple its program. There are 12 residents
in training to become family practitioners. This will be expanded to
36 with the admission of 12 new graduates for two years. This center
is o n e of 52 in the nation to share a total of $5 million allocated by
the Division of Physician and Health Professions Education of the
Bureau of Health Manpower Education, U. S. Department of Health,
Education and Welfare.
Dr. Ernest R. Haynes is director of the Family Practice Center
which opened in October, 1970. The residents, who train here,
spend their first year in the nearby hospital, coming to the center
periodically for conferences and to see patients. The second and
third years are spent at the center treating their own patients. There
is a volunteer faculty of 12 family practitioners and more than 40
others, including other medical specialists, nurses, clergymen and
social workers. There are 800 families consisting of more than
3,000 individuals enrolled in the program.
Dr. Haynes said he plans to add a full time internist and a full
time psychiatrist to his staff. The physical facilities of the center
will also be expanded.
A second grant of $50,000 a year for two years from the Lakes
Area Regional Medical Program is being used to study the results
of the center's health care team concept in preventing and curing
disease. This program is closely affiliated with the newly-created
department of family practice at the Medical School.•

Dr. Murphy Promoted
Dr. Walter T. Murphy, who has been chief of the department of
radiation therapy at the Buffalo General Hospital since 1963, has
been promoted to consultant of the department. The 65-year-old
physician is a clinical associate professor of radiology at the Medical
School. He is a 1930 Medical School graduate and did his surgical
internship and residency at St. Francis Hospital, New York City.
Dr. Yehuda Laor, who worked with Dr. Murphy for nine years,
will be the new Chief of the department. Dr. Murphy will continue
working in the department. The two physicians are looking forward
to new facilities that are part of the hospital's expansion program.
Currently the department treats about 100 patients a day in radia­
tion therapy and another 100 per week in the division of nuclear
medicine
Dr. Laor, a clinical associate in radiology at the Medical School,
was born in Germany. He moved to Israel (then Palestine) as a child
and was graduated from the Medical School of the University of
Zurich, Switzerland in 1957. He returned to Israel for his internship
and residency, then came to the Roswell Park Memorial Institute
in 1962. He joined the Buffalo General Hospital in 1 9 6 4 . •
WINTER, 1972

39

Family Practice
Receives Grant

Dr. John H. Siegel is the new head of the department of surgery at
the Buffalo General Hospital and professor of surgery at the School
of Medicine. Dr. Siegel, who has been an associate professor of
surgery at Albert Einstein College of Medicine in New York City,
took over his new duties September 15.
Dr. Theodore T. Jacobs, president of the hospital, said "Dr.
Siegel brings to Buffalo an outstanding record of accomplishment
in a broad area of medicine and surgery." The 39-year-old Dr.
Siegel becomes the first head of surgery at the hospital since the
retirement of Dr. John R. Paine in July, 1969. Dr. Elmer Milch of
the BGH Medical Staff had been serving as acting head of the de­
partment.

Dr. Siegel

Dr. Siegel Named
Surgery Chairman

Dr. Siegel was Director of the Renal Transplantation Service
at Albert Einstein and Associate Director of the Clinical Research
Center-Acute at the same college. He was an attending surgeon
at the hospital of the Albert Einstein College, as well as at the Bronx
Muncipal Hospital Center.
Born in Baltimore, Md., Dr. Siegel graduated from Cornell
University in 1953 and received his medical degree from Johns
Hopkins University in 1957. He served a straight surgical internship
at Grace-New Haven Community Hospital-Yale Medical Center in
1957-1958 and did his residency in the department of surgery at the
University of Michigan Medical Center from 1961 to 1965.
His research training included being a Henry Strong Denison
Fellow in Pharmacology at Johns Hopkins University from 1956 to
1957; a Cardiovascular Fellow, Department of Surgery, Yale Univer­
sity, 1958-1959; at the Laboratory of Cardiovascular Physiology,
National Heart Institute, 1959-1961, and in Academic Surgery, De­
partment of Surgery, University of Michigan, 1962-1965.
Dr. Siegel was director of the Cardiovascular Physiology Labora­
tory, Department of Surgery, University of Michigan School of
Medicine, from 1962 to 1965. He then joined Albert Einstein as an
instructor in surgery, becoming an assistant professor of surgery in
1967 and an associate professor of surgery in 1970. He has been an
attending surgeon at the hospital there since 1966.
Dr. Siegel has been the principal investigator in several projects
for the National Heart Institute, as well as the National Institute of
General Medical Sciences. He has published nearly 80 papers, many
of them involving the use of computers to aid diagnosis of various
conditions.
Dr. Siegel recently took the lead role in implementing the use
of computers to more accurately diagnose the conditions of patients
who have suffered heart attacks. As reported in "Newsweek"
magazine on April 3 (1972), Dr. Siegel, in collaboration with experts
from IBM, used a small computer at the bedside of patients in the
Clinical Research Center-Acute at Albert Einstein to more precisely
decipher the results of cardiac catheterization.
By use of the computer, Dr. Siegel and his research team found
that they could obtain much more critical information from the
chart. They found that the dye dilution curve on the chart would
indicate the heart's pumping power and the area of heart muscle
40

THE BUFFALO PHYSICIAN

which is actually damaged. Using this data, the doctors could
determine whether the patient's heart needed immediate mechanical
support or surgery. Dr. Siegel said these indications were often
obvious some hours before ordinary clinical signs of the patient's
decline became evident, thus enabling doctors to make faster deci­
sions on methods to save the patient's life.D

D r . P e t e r F. R e g a n , p r o f e s s o r o f p s y c h i a t r y a t t h e M e d i c a l S c h o o l ,
has accepted a two-year appointment in Paris, France to head a
study of the health care education and services of several foreign
countries. Dr. Regan will serve as consultant to the Organization
for Economic Cooperation and Development (OECD) which is
sponsoring the study.

T>

A

"dYlS /lppOintment
pQy P)p Pj>pafi
'
&

Dr. Regan explained that the study will involve a comparative
international approach. "There are 24 nations which belong to the
OECD and virtually all of these countries are in a turmoil regarding
health care education and the resulting health care services," he said.
Working out of the OECD headquarters in Paris, Dr. Regan
will review the various ways in which these nations have structured
their health care education system to meet actual service demands.
As an example, Dr. Regan noted that there are approximately 200
health related professions. "It is necessary," he continued, "that
persons from all these professions work together, but how well is a
given country's health education system preparing its students to
work together?" Dr. Regan indicated that the specific countries
which will be involved in the study have not yet been determined.
Dr. Regan joined the U/B faculty in 1964 as vice president for
health affairs. In 1967 he was appointed U/B executive vice presi­
dent and served in 1969-70 as acting president of the University.
Fie is presently a full professor of psychiatry and adjunct professor
of higher education. A native of Brooklyn, Dr. Regan is a graduate
of the Cornell University Medical College.D

Three Medical School alumni opened a Family Practice Medical
Center in Wyoming County Community Hospital in July at Warsaw,
N. Y. Drs. Michael Smallwood and Robert Gibson, both of t h e class
of 1969 and Frederick R. Downs, M'70, are the first group returning
to the county under terms of the scholarships they received to help
defray their medical education expenses. The three physicians have
completed their residency in the family practice program at Deac­
oness Hospital, Buffalo. Dr. Gibson has two years of military service
to complete before joining his colleagues in Warsaw.
The Center will not be a clinic, but a private operation inde­
pendent of hospital administration. The physicians want to provide
continual, not periodical, health care for families in the area.
There have been 10 scholarship students since 1964 and seven
plan to practice in the county. The others dropped out to practice
elsewhere.Q
WINTER, 1972

41

Rural Area
Scholarships

RESEARCH STUDIES by a professor of biochemistry at the School
of Medicine may not only help toward developing a better means
of fertility control but improve those that are now available (the pill,
etc.). Dr. Om Bahl has successfully isolated and analyzed a hormone
from human pregnancy urine. It is the human chorionic gona­
dotropin or HCG, as it is termed, and becomes the first hormone
of such complexity whose complete structure we now know. Pro­
duced by the placenta during pregnancy, it is responsible for the
maintenance of pregnancy and early growth of the embryo. While
production levels of this hormone rise during pregnancy, in certain
types of cancer of the uterus that resembles pregnancy, production
levels are even greater.
Said the India born and University of Minnesota trained scien­
tist (Ph.D. biochemistry 1962), "not only can we now separate the
two subunits of this molecule (its 231 amino acids and 55 sugars)
but we can recombine them in the laboratory as well. And when
we fully understand how this hormone works — our next phase of
research is to unravel its various metabolic steps leading to an
understanding of its complete mechanism of action — we will de­
velop a means of suppressing ovulation and thus prevent preg­
nancy."
Malfunction of this hormone — one of its subunits may be
formed in excess — may be responsible for certain diseases as well.
Underway is a study by Dr. Bahl on the relation of this hormone to
other complex molecules that may have a different function (such as
thyroid stimulating hormone; other polypeptide sex hormones) but
still share something in common with HCG.
In a study on hormones produced during cancer of the uterus,
Dr. Bahl is seeking the relationship to its cause as well as looking
into other disease states where production of this hormone is
greater than normal. In order to successfully analyze such a com­
plex molecule, painstaking plans had to be formulated. Said Dr.
Bahl, "many of the postdoctoral fellows in my training program
have contributed to this research."
To analyze the carbohydrate portion of the molecule, specific
enzymes were first isolated and characterized in the laboratory.
Working on this phase from 1966 to 1968 was Dr. K. M. L. Agrawal.
In characterizing the enzymes, specific chemical compounds had
to be synthesized in the laboratory. From 1969 to 1971 Dr. K. L.
Matta worked on syntheses of enzyme substrates. This was followed
by successful application of enzymes to structure. Determination
of the complex structure of protein came next. And the method
used to separate for the first time the subunits of this molecule (on
the beta subunit structure of HCG Dr. N. Swaminthan from 1970-71
and Dr. Robert B. Carlsen from 1971-present; on alpha subunit
structure Dr. Ronald Bellisario from 1971 to present) are now
being applied to the study of other sex hormones.
All of these tools, which were developed in the Buffalo lab­
oratories to understand the structure of the HCG hormone are being
applied to similar molecules involved in other key metabolic roles
such as cystic fibrosis. They will be used on the next phase of their
research — relating structure to hormone function, explained Dr.
42

THE BUFFALO PHYSICIAN

Bahl, who is now attempting to determine the primary site of action
in the cell as well as isolate the receptor protein for HCG and other
related protein sex hormones. By using modified forms of HCG
a n d r e l a t e d h o r m o n e s h e w i l l s e e if a n y w i l l a c t a s i n h i b i t o r t o s u p ­
press ovulation and thus control fertility.
Grants from the Population Council and the National Institutes
of Health over a five year period in the range of about $200,000
have supported the five long years of carefully planned research
that has led to the complete understanding of the structure of
the first human hormone of such complexity, HCG.Q

Dr. Vaughan Lab
The Hematology Teaching Laboratory of Buffalo General Hospital
h a s b e e n n a m e d t h e D r . S t u a r t L. V a u g h a n L a b o r a t o r y i n h o n o r o f
the hospital's former director of clinical pathology and hematology.
He was also director of its School of Medical Technology for 26
years. Dr. Vaughan, a 1924 Medical School graduate, died April 3,
1972. He was on the Medical School faculty for 43 years and joined
the hospital staff in 1931. Dr. Vaughan served as director of clinical
pathology and hematology from 1936 to 1966.
A plaque bearing the new name of the teaching laboratory has
been placed near its door. A second plaque memorializing Dr.
Vaughan's "outstanding services" has been hung near the main
door to the Hematology Laboratories.•

Construction has started for
the $91 million Comprehen­
sive Health Care Center adja­
cent to the E. I. Meyer Me­
morial Hospital. Five con­
tracts totaling $23.4 million
have been awarded. Erie
County expects to occupy
the new facility in 1975.

Finding
Cause of
Infectious
Diseases
Quicker

Dr. Caret ). van Oss (right) and Mr. Cetewayo F. Cillman (sitting, left), with the contact angle
measuring apparatus. Mr. Cillman is depositing a drop of saline water on top of a fiat layer of
bacteria, in order to measure its contact angle with the help of the telescope and goniometer,
visible somewhat to the left of the middle in the photograph. Mr. Cillman is now writing his
doctoral dissertation on this application of the contact angle method.

A quick and easy test to determine the culprit for making a patient
ill has resulted from the studies of microbiologist, Dr. Carel J. van
Oss. In the body's first line of defense against disease, a process
known as phagocytosis, bacteria are "eaten up" or destroyed by
our white cells or neutrophils as they are called.
Dr. Carel van Oss is editing
three scientific journals. He is ex­
ecutive editor of "Preparative Bio­
chemistry," an international jour­
nal for rapid communication de­
voted to preparative methods and
procedures in biological, immuno­
logical, pharmaceutical and clin­
ical chemistry, molecular biology,
biochemistry and biophysics. He
is co-editor of "Separation and
Purification Methods," a new jour­
nal that will cover all areas involv­
ing the separation and purification
of both simple and complex com­
pounds. Articles will deal with the
separations of inorganic and or­
ganic substances as well as bio­
logical materials. The professor of
microbiology is also on the edi­
torial committee of another new
journal, "Immunological Commu­
nications." This international pub­
lication has been founded by The
Center for Immunology at the
Medical School. It will be devoted
to promoting, on a world-wide
basis, the rapid dissemination of
original work on all aspects of
immunology.

"But," explained the professor of microbiology, "because bac­
teria differ in their surface properties, some get eaten up faster than
others. When this rate of destruction is fast enough, we remain in
good health. And when it is not, the invading cells go haywire and
we get sick."
Dr. van Oss has identified and measured the surface properties
of different species of bacteria. He has correlated these data with
the speed at which our white cells phagocytise or eat up various
types of bacteria. This has been determined by the use of contact
angles that a drop of saline water make with a flat layer of cells.
In this very easy method that takes only a few moments, the angle
reveals whether a dangerous germ is involved or not. If the
bacterium is more hydrophobic than white cells, the angle will be
larger than that of white cells and they will get eaten. When they
are more hydrophilic they get wetted more easily and their contact
angle is lower than that of white cells. These are the dangerous
ones!
However antibodies and complement can aid in increasing the
angle, explained Dr. van Oss. Circulating neutrophils are like
policemen. As soon as bacteria become sufficiently hydrophobic
they get eaten up. The dangerous ones — the hydrophilics — are
those that do not get recognized by the policemen or white cells.
By tagging them with antibodies they will become more hydro­
phobic and thus get eaten up.
44

THE BUFFALO PHYSICIAN

The thermodynamics, which very satisfactorily explains why
particles are ingested by white cells, was developed together with
Dr. Wilhelm Neumann while he was working at SUNYAB's depart­
ment of chemical engineering (he is now at the University of
Toronto). He succeeded in translating contact angles into interfacial free energies (something like surface tensions). Graduate
s t u d e n t C e t e w a y o F. G i l l m a n c o n t r i b u t e d m u c h t o t h e m e t h o d o l o g y
on contact angles.
Said Dr. van Oss, these studies will also allow us to look for a
new class of antibiotics that will help to increase the contact angle
of bacteria and thus encourage phagocytosis to take place in in­
fectious diseases.D

VA Hospital Director
Mr. Joseph Paris, former assistant director of the Buffalo Veterans
Hospital, succeeded John R. Rowan as director July 1. Mr. Rowan
will become director of the Veterans Hospital in Lexington,
Kentucky. Mr. Paris has been director of the Butler, Pa., Veterans
Hospital since January 1971. He began his VA career in October,
1945. In 1955 h e was named assistant director of t h e Batavia, N. Y.
VA Hospital. He came to Buffalo in the same capacity in 1968.
The new director plans to keep his hospital in the forefront of
medical technology. He noted that it is the nation's only hospital
licensed to perform nuclear-powered heart pacemaker implants.
" M e d i c i n e i s c o n s t a n t l y c h a n g i n g a n d if w e d o n ' t k e e p u p w i t h i t
we'll be left behind. We're going to be in the business of implanting
both nuclear and conventional pacemaker here for quite a while,"
Mr. Paris said.
"Continuing close contact with the Medical School at the
University is vital to successful patient care. By working with the
Medical School we can develop our own potential to a maximum.
"We also plan to expand the VA Hospital's connections with
other city hospitals and regional VA hospitals. A program of com­
bining our resources is necessary because we've got to bring the
high costs of hospitalization down. We can't keep competing and
duplicating costly equipment and specialists' expertise in each
hospital. A regionalization plan for Western New York VA Hospitals
is now taking shape to make them all like one big hospital," the
new director said.
Mr. Paris sees his role as a three-pronged mission—patient care,
education and research. In the area of patient care he hopes to
develop a more sophisticated out-patient treatment clinic. He said
the hospital is now drawing up plans for an ambulatory patient
building "so we won't have to tell people who just have a cold to
wait and come back for treatment when they have pneumonia.
Also in the future plans is a new research building."•
WINTER, 1972

45

Two nurses with a patient in the clinic.

The Lackawanna Community Health Center

Dr. Arthur R. Goshin, clinical instruc­
tor in social and preventive medicine,
and director ot the clinic.

When Arthur R. Goshin was a third year medical student in 1968,
he, several of his classmates, and some community residents had an
idea. They wanted to do something about providing first-class
health services in certain medically disadvantaged areas. Today,
Dr. Goshin is directing that idea, the Lackawanna Community Health
Center.
"I am pleased with the enthusiastic acceptance of the Health
Center by the community. An estimated 25,000 patient visits will
be made at the Center this year," Dr. Goshin said.
"The Health Center is attempting to provide to the community
a comprehensive system of family-oriented health services. Em­
phasis is placed upon preventive and health maintenance care rather
than episodic, acute-illness services. Medical care is of the highest
quality and being rendered in a numane, personal, dignified manner.
The Center is open from 9 a.m. to 9 p.m. Monday-Friday and from
10 a.m. to 1 p.m. weekends. An answering service puts a patient
in touch with a physician at all other hours around the clock."
46

THE BUFFALO PHYSICIAN

The
island of
rounded
dentists.

community is Lackawanna's First Ward. It is a residential
7500 persons in some 2000 families whose homes are sur­
by industry. It has only one part-time physician and no
The Health Center at 33 Wilkesbarre fills the void.

Besides Dr. Coshin there are three full-time physicians—Drs.
Jack Piazza and Carol Segal, both internists, and Dr. K. Vishnu Jain,
a pediatrician. There are about 20 other part-time physicians work­
ing at the Center. The rest of the staff includes: four public health
nurses, three licensed practical nurses, four senior public health
aides, one nutritionist, one caseworker, one laboratory technician,
two laboratory assistants, one X-ray technician, five office staff, two
dental assistants, five part-time dentists, one dental hygienist, one
bus driver. Most employees are residents of the 1st Ward Com­
munity.

Dr. Carol Segal, clinical associate in
medicine, with a teen-age patient.

A family health worker, Barbara Swygert, visits with a patient at her home.

The Health Center staff is divided into two multi-disciplinary
health care teams. Each team is responsible for coordinating and
providing primary services to about 1000 families. Sharing of re­
sponsibilities and team review of family health problems are the
rule. Emphasis is placed upon problem follow-up and home visits.
In addition, the mental health staff consisting of part-time psychi­
atrist, psychologist and psychiatric nurse frequently make family
home visits. All mental health staff are affiliated with Unit 6 of
Meyer Hospital.
The Health Center operates under the aegis of the Erie County
Health Department. Using the Lackawanna Center as a model, Dr.
Goshin and the Health Department plan to open two additional
family health centers this year within Buffalo's inner-city area. Addi­
tional such centers are on the drawing board for other areas of
need within the County.
The principal financial support for the program comes from
collection of fees from patients' health insurance — Medicaid, Blue
Cross and Blue Shield, etc. Any deficit is shared equally by the
County and the State.
The Health Center has a Board of Directors made up of con­
sumers of Health Center services. They are involved in establishing
all major policies, hiring of all personnel, investigating all grievances.
This board helps to ensure that services will remain relevant and ac­
countable to the community.
The Health Center is also now operating the Addiction Treat­
ment and Rehabilitation Program. This program provides a wide
range of medical, social and rehabilitative services to drug addicts.
Methadone maintenance is one of the treatment modalities now
being utilized. The program, when fully operating, will have a staff
of about 30 treating over 300 heroin addicts.D
WINTER, 1972

47

Dr. tin Woong Rho, clinical instructor
in gynecology-obstetrics, visits with a
patient.

"The public must be better informed on health resources," accord­
ing to a Louisiana physician. Dr. Joseph A. Sabatier told area health
officials that individuals want their health problems and those of
their relatives and friends solved immediately. "They expect this
because of the tremendous advances made in science in the last
decade or two."

Health
Resources

The director of the Louisiana Regional Medical Program said
"there must be a more appropriate distribution of benefits of
science so that the general public can reap the profits and pleasures
of scientific planning for health care to prospective planning for
community commitment for health. We must increase our capacity
for quality and quantity of service to the people.
"We must have conversation between the providers and con­
sumers — conversation that is understood by all. The fate of RMP's
depends upon all of us getting across to the community the specific
information that identifies it with the community. RMP must be a
real asset to all people involved in the delivery of health care,"
Dr. Sabatier said.
In conclusion the physician said, "RMP must win public sup­
port by solving people's health problems. When this happens we
will be accepted because we have developed a consistent image."

•

•pv

t

p

i*

Ur. l^araglia
RctlfCS

A physician who never refused a request for a house call (unless
jn May after a 53-year career in

he was too sic|< to go) retjrec|

Dunkirk, New York. Dr. Joseph R. LaPaglia Sr., a 1919 Medical
School graduate served his internship at St. Mary's Hospital, Roch­
ester.
He was graduated from the Fredonia Normal School where he
won a $100 Regents Scholarship. But the scholarship was not
allowed at the UB Medical School. Two years later, in 1917, his
class was disbanded and he entered the U. S. Army. During the
1918 Asian influenza epidemic he was assigned to Columbus Hos­
pital, then a 35-bed institution in Buffalo. He returned to Medical
School later the same year.
Dr. LaPaglia's interest in people overflowed into his personal
life. He used his free time to serve his community as public school
physician, school board member, city board of health and the selec­
tive service system. He has signed citations from four PresidentsHarry S. Truman, Dwight D. Eisenhower, Lyndon B. Johnson, Richard
M. Nixon—for his dedicated and uncompensated service for the
Selective Service System. Dr. LaPaglia also has an engraved bronze
medal from President Truman and a special citation from President
Johnson.
In 1968 friends and citizens recognized Dr. LaPaglia for his
long service in Fredonia. The following year the Medical Society
of New York State honored the physician for his professional con­
tributions. Dr. LaPaglia is living with his son at 39 Longbrook Drive,
Byfield, Massachusetts.D
48

THE BUFFALO PHYSICIAN

Experimental Surgery
Providing an understanding of the importance of humane use of
live animals in biomedical research is among the objectives of a
unique graduate course, being offered for the first time this sum­
mer, by the department of laboratory animal science, at the Uni­
versity.
"Introduction to Experimental Surgery" is unique in several
ways. Thirty graduate students from a variety of undergraduate
backgrounds, some only indirectly related to animal research, are
enrolled in the course. And it is possibly the only course of its
kind available to students who do not possess a professional
background in surgery.
Dr. Thurman S. Grafton, director of the animal laboratory
facilities, noted that at present a two-semester course in experi­
mental surgery is taught, but it is open only to those having a
professional surgical background.
"We noticed an obvious interest in experimental surgery by
other graduate students. Thus in an attempt to accommodate
these students, we designed this special introductory-level course.
The response has been overwhelming," Dr. Grafton said.
"Students taking the course come from a wide variety of
disciplines including micro-biology, physiology, health sciences
education and evaluation and Pharmacology. Each student has his
own thoughts on how the course will help him with research in the
particular discipline," he added.
Dr. Shaheen M. Al-Nakeeb, associate professor in laboratory
animal science who is the primary instructor of the new course,
stated that serious regard is given to the humane aspects of con­
ducting research with animals.
"The course begins with an introduction which deals with
respect for living tissue, emphasis on humane care and handling of
animals and the regulations governing the use of live animals.
We are careful to make sure that each student realizes these aspects
before conducting any animal surgery," Dr. Al-Nakeeb said.
Preceding any actual surgery there are introductions to an­
atomy and physiology, anesthesiology, microbiology and surgical
instrumentation and equipment.
"These introductions enable a graduate student of any of the
biological sciences to carry out certain select experimental, sur­
gical procedures on animals, and to utilize such skills in research
within his own discipline. It is not intended to produce skilled
surgeons in this short time," Dr. Al-Nakeeb added.
Summing up the apparent success of the course, which has
only been in existence a few weeks, Drs. Grafton and Al-Nakeeb
both expressed favor in the sincere interest shown thus far by the
students, terming it an "enthusiasm that is delightfully stimulating."D
WINTER, 1972

49

Dr. Al-Nakeeb (left) and Dr. Thurman
5. Crafton, director of the laboratory
animal facilities, prepare to use an
intravenous anesthetic agent on one
ot the lab's pets.

VA Hospital Treats Veterans on Drugs
The primary commitment of the drug program at the Veterans Ad­
ministration Hospital has been described as a "therapeutic com­
munity." This means that the program depends more on the basis
of person-to-person relationships among residents and staff than
on chemotherapy such as methadone. "A therapeutic community,"
explained one of the resident addicts, "does work in finding out
what the problem is." Once this is done, he said, "he has no need
for drugs."
The Drug Dependence Treatment Center (Ward 10C) is re­
ferred to as EPIC House (Encountering People in Crisis). It is headed
by Dr. Peter Russell, program coordinator and clinical psychologist.
The Center opened in July of 1971.
Dr. Russell explained that there are three separate phases in
the long-term program. The first phase is the Detoxification and
Evaluation Unit (DEU). EPIC House is the second phase, and the
outpatient treatment program is the final stage. The DEU unit has
20 beds and is the initial admittance ward for all those asking
entrance to EPIC House. A veteran who comes to the hospital
with a drug problem is immediately given a bed, Dr. Russell
pointed out, "as long as he is eligible" (a dishonorable discharge
prevents this). He is interviewed first, said Dr. Russell, "then shaken
down. We want to make absolutely sure he's clean."
Methadone is used in detoxification, according to Dr. Russell,
but controlled "very, very carefully." The complete process takes
from one week to ten days, perhaps longer "depending on the size
of his habit." While the program handles mainly heroin addicts,
users of other addictive drugs are also treated.
"Our main idea is to get this fellow away from the street, give
him a chance to get his head together and make an appropriate
decision: 'What do I want to do with my life'?" The individual
then participates in various types of therapy including group, indi­
vidual, occupational and recreational. He also gets daily medical
checkups. "It's really a rather full schedule," added Dr. Russell,
"and always oriented toward the idea, 'What are you going to do?
What's your contract with us'?"

graduate work at the University of
Rochester and received his M.A.
and Ph.D. degrees from Penn
State.•

The contract is one of three kinds: simple detoxification (the
person is given a regular discharge at the end of "detox": secondly,
referral to other community drug programs (DDTC often refers
people who consider the program too hard to other agencies
such as methadone maintenance programs). The third type of
50

THE BUFFALO PHYSICIAN

contract is to request admittance to EPIC House. "This," Dr. Russell
said, "is where the commitment is. All the rest is very important,
but it's just a stepping stone."
Prior to entering EPIC House, one must first, if recommended
by the DEU staff, appear before a screening committee. Here, Dr.
Russell said, the individual is questioned "very thoroughly" on his
motive for wanting to join EPIC House's long term treatment pro­
gram. Upon gaining the screening committee's approval, one is
placed on Level 1. He would then participate in certain house
activities and simply observe others. Level 1, according to Dr.
Russell, gives an individual the opportunity to see EPIC House and
how it operates, and also gives the residents and staff a chance to
get to know the prospective resident. After a week at Level 1, the
person is again screened. At this screening, the individual tells the
committee what he thinks of the House so far and the committee
members tell the individual their opinion of him.
Promotion to Levels 2-6 entails increased responsibilities and
privileges for the resident. For the first few levels, the resident is
responsible only for himself and his actions, but as he progresses,
explained Dr. Russell, he is expected to realize responsibilities for
other, newer residents, and for the day-to-day operation of the
House. An older resident said that it was his responsibility to "pull
sheets off" someone breaking the rules, but he explained he
doesn't see it as responsibility, but "more like caring."
The complete EPIC House program takes about five months.
Dr. Russell pointed out that the time varies for each level. "Each
of the first five levels takes generally three weeks while Level 6
takes about six weeks." During residency the patient seldom moves
out of the hospital, but at Level 4 he gets off-ward privileges and by
Level 6 he can obtain weekend passes, day care rights (where the
resident can be with his family), and work passes to prepare him for
the outside world.
The atmosphere in EPIC House is one of community involve­
ment to help individuals work out problems which must be dealt
with in order to lead a drug-free, constructive life. In working
toward this goal, residents take an active part in encounter groups,
individual counseling, entertainment, educational seminars, work
projects, job placement and many other types of therapy.
Mail is the only legal contact with anyone on the outside until
Level 4, and this is opened in the presence of a staff counselor and
searched for contraband. The resident is encouraged to talk over
mail received or sent with the counselor. "The more we as a staff
can learn and get inside the fellow's head, the more we can help
him to reorient to the outside world," Dr. Russell said.
The final phase of the program is Outpatient Treatment. This is
primarily for the graduated residents of EPIC House, although in
certain isolated instances it may be available to patients who have
participated only in DEU. "The purpose of this phase of treatment
is to help the individual complete his readjustment to the community-at-Iarge and maintain a stable, drug-free life," Dr. Russell
concluded.•
WINTER, 1972

51

Mr. David Lowalewski, a social
worker on Dr. Russell's staff em­
phasized three points: (1) "the
program is open to all eligible
veterans; (2) the program isn't the
free and easy ride to rehabilita­
tion, rather a tough, total com­
mitment, no-nonsense approach;
(3) the program works for some­
body who really wants to get
straight and stay straight."•

Three other VA hospitals in
Battle Creek, Michigan, Salem,
Virginia and Syracuse, New York
have similar programs.D

An informal conference for professionals and paraprofessionals.

Mental Health
"There is no easy road to success in the mental health field. Patience
and firm conviction about the necessity for hard work and contin­
uous learning is always in order." This is what Dr. Francine Sobey,
a professor of social work at Columbia University, told some 150
mental health practitioners of Western New York at a Education
and Training Team workshop. Dr. Sobey, who has written a book
about "the nonprofessional revolution in mental health," was the
keynote speaker.
"Both professional and paraprofessionals have new roles to play
in stimulating the development of peer-groups, offering appropriate
groups leadership skills and providing liaison. Newer levels include
the social advocate and the ombudsman or mediator," Dr. Sobey
said.
In commenting on the sudden economic slump that has affected
many social services across the nation the educator said, "human
needs can not be cut like budgets. There is statistical evidence of
greater need in times of unemployment."D
THE BUFFALO PHYSICIAN

li

"Sure I got seasick," said Senior Assistant Surgeon Lawrence Frankel
of the U. S. Public Health Service, "But then, so did most of the
Commanders and Lieutenants."
He hastily added with a twinkle in his eyes, "not too many
of the bos'ns got sick though."
Dr. Frankel, a 1970 graduate of University of Buffalo Medical
School did his interning at Georgetown University hospital in
Washington, D. C. He is the son of Mr. and Mrs. Joseph Frankel
of Syosset, Long Island, N. Y. He graduated from Syosset High
School in 1963.

10,000 Mile Cruise
for Dr. Frankel

Dr. Frankel is now at sea completing the last leg of a 10,000
mile cruise that has taken him from Little Creek, Va., through the
Panama Canal, plus liberty stops at Acapulco, Mexico and Hono­
lulu, Hawaii. The cruise will end at Guam in early May.
He provides medical attention for the nearly 300 active duty
and Reserve Coast Guardsmen engaged in transferring three vessels
from the East Coast to Guam. The three ships, the Cutters ABSECON,
CHINCONEAGUE and McCULLOUCH, are to be transferred to the
Navy as part of the President's program to reduce Federal ex­
penditures. The Coast Guard's reduction included the loss of 10
ships, several stations and 2,000 men.
The three ships are scheduled to be turned over to the Navy
around May 10. Dr. Frankel and the Coast Guard crews will
return to their duty stations at that time. "Doc" will return to
Yorktown, Va. where he provides medical attention for Coast
Guard and Naval personnel and their dependents.
Frankel, who has had special training in pediatrics and internal
medicine, said, "Fortunately, there have been very few real prob­
lems during the cruise. It's almost like a vacation for me. But,
I'm here in case of an emergency. Like an insurance policy, you
might say."
Frankel and the Coast Guardsmen left Little Creek, Va. in
mid-March on a cold damp day. With a drastic change in climates,
Dr. Frankel found treating sunburn cases and heat exhaustion
taking up much of his time. He has also been busy inoculating
the nearly 300 men against Cholera, Yellow Fever, Smallpox, Ty­
phoid, Diphtheria and Tetanus because of the epidemic areas on
the cruise schedule.
The officers in the wardroom say that "Doc" Frankel has truly
added color to the cruise. As a matter of fact, it was the dye from
his blue sweatshirt that changed the officers' khaki colored socks
to an attractive powder blue.
Dr. Frankel also serves as the Morale Officer for the Cutter
ABSECON, providing movies for off hour entertainment, informa­
tion on ports to be visited, beach parties, general counseling and
host of shipboard recreational activities.
Dr. Frankel is married and has o n e child. He will serve with
the Coast Guard until June 1973, when he will enter private prac­
tice. It is a sure bet that the Coast Guardsmen will miss his ex­
cellent health care and ability to add some fun into life

.n

WINTER, 1972

53

Dr. Frankel's Coast Guard duty
started in 1971 and ended in May.
As a uniformed Public Health Serv­
ice doctor, he enjoyed his sea
duty. The 26-year-old was well
liked and admired by Coast Guard
officers and enlisted members.EJ

Allegany County Medical Van
A

SELF-SUFFICIENT, multi-purpose medical van is bringing health
education and preventive health care services to Allegany County in
southern New York state. The $52,000 unit was purchased by the
Lakes Area Regional Medical Program. It is operated by the Alfred
University School of Nursing in co-operation with the Allegany
County Public Health Nursing Service.
"This is the only unit of its type in the world. We have had
inquiries from countries in the Middle East and several states from
coast to coast," Dr. Virginia Barker said. She is mobile projects
director and dean of the Alfred University Nursing School.
D r . Barker

"The response of people living in Angelica, Caneadea, Richburg,
Whitesville and Alfred to our services has been overwhelming,"
Dean Barker said. Health-education classes and "health assessment"
examinations of children and adults are the two main categories
of service. The unit provides vision and hearing tests, blood sugar
screenings, urinalyses and other tests designed to indicate deviations
from normal patterns. Suspected cases of illness or health de­
ficiencies are referred to family physicians. Allegany County's two
hospitals, Cuba Memorial in Cuba and Jones Memorial in Wellsville,
are available for residents who have no family physician
Mrs. Margaret Connelly pointed out that there are only 16
physicians providing primary health care in Allegany County (popu­
lation 46,500). She is director of nursing for the county public health
service. Mrs. Connelly's staff of five public health nurses, five reg­
istered nurses, one physical therapist, one speech therapist and 12
home health aides are participating in the project along with nursing
students and faculty from Alfred University.
Dean Barker emphasized that the nurses are not practicing
medicine. "Our slogan is 'don't' wait until you get sick."Q
54

THE BUFFALO PHYSICIAN

New North Campus
The new North Campus in Amherst is becoming a reality. By 1977
more than half of UB will be at the new campus. Dormitories
d e s i g n e d b y a r c h i t e c t I. M . P e i w i t h s l e e p i n g c a p a c i t y f o r 8 2 0 s t u ­
dents are expected to be ready for occupancy in January (1973) at
the 1200-acre North Campus, according to Dr. John D. Telfer, vice
president for facilities planning. Construction currently under way
or completed at the North Campus totals $115 million, but much of
it is in site preparation and utilities installation. Plans now call for
conversion of the present South Campus on Main Street to a healthsciences oriented campus. There will be no mass exodus to the
North Campus. The conversion will be "building by building" due
to the staggered funding by the Legislature as monies become
available, Dr. Telfer said.n

Heart/Lung Studies

Dr. Francis Klocke and Ann Salter, ad­
ministrative assistant lor the heart/lung
program, check order lor new com­
puter.

A two million dollar National Institutes of Health grant to a medical/
engineering team at the University over the next five years assures
continuation of studies on heart and lung diseases. Said its principal
investigator, Dr. Francis J. Klocke who is professor of medicine,
assistant professor of physiology at the University, and chief of
cardiology at the E. J. Meyer Memorial Hospital, "we hope to im­
prove our understanding of abnormal physiological processes in
specific cardiovascular and pulmonary diseases so that we can de­
velop better treatment of established disease and methods for
earlier detection of latent disease."
With senior investigators Dr. David G. Greene (professor of
medicine and associate professor of physiology), Dr. Robert A.
Klocke (assistant professor of medicine), Dr. Robert E. Mates (pro­
fessor of mechanical engineering and research associate professor
of medicine), and Dr. Stephen M. Wittenberg (associate professor
of medicine), 19 other physicians will carry on investigations in a
research program begun seven years ago that is now attracting
national attention at the Buffalo General and E. J. Meyer Memorial
Hospitals as well as at the School of Medicine.
Studies on the coronary circulation — its normal physiology
and its alterations in coronary artery disease and hypertrophy states

Dr. Djavad Arani, clinical assistant professor of medicine, Mrs. Cretchen Smith, chief
research nurse, look over material related to a study in cardiac catheterization with
Drs. Greene and Bunnell.

56

THE BUFFALO PHYSICIAN

Dr. Robert Klocke and technician Anne Coe measure rates of reaction of oxygen with red
blood cells on continuous flow reaction apparatus.

— are directed by Drs. F. Klocke, Greene and Ivan L. Bunnell who
is associate professor of medicine. Agreed Drs. Greene and Bunnell,
"methods developed earlier to document reduction of flow in pa­
tients with coronary disease are now being used to evaluate patients
with chest pain and specific coronary arteriographic patterns." These
methods are utilized when diagnostic studies are made in the
cardiac catheterization laboratory. They involve the breathing of
inert gases such as helium and the sampling of arterial and coronary
sinus blood.
There are also studies underway in the operating room with
associate professor of surgery, Dr. George Schimert, to evaluate the
effect of venous bypass grafts as well as a variety of supportive
studies in animal experimentation.
Another aspect of the program will focus on mechanisms of
arrythmia production. There are now two experimental models
available for the study of arrythmias — injury to the heart and digi­
talis overdose. Past studies of the Meyer Hospital and other groups
have revealed that variations in heart rate profoundly alter the
development and persistence of certain rhythm disorders.
WINTER, 1972

57

Under Dr. Wittenberg the Meyer group is focusing on the role
which beat-to-beat changes in rate play in the development of
digitalis-induced arrythmias. This is being done in intact animals,
said Dr. Wittenberg, and in single heart cells. "The hope is that
with these powerful laboratory tools, we will arrive at a better under­
standing of the immediate determinants of arrythmia in man," he
said.

Dr. Mates looks over computer output
on a math model of blood flow in the
coronary circulation.

In investigations on gas exchange the investigators are looking
for factors that cause mismatching of ventilation and blood flow in
the lungs as well as a better understanding of frequency distribution
of these ratios throughout the lungs in both normal and abnormal
states. For in a number of lung diseases, such as pneumonia and
emphysema, patients have very low oxygen content in their blood.
Determining the speed at which the gas exchange occurs in the
lungs and duplicating its physiologic picture in the laboratory are
investigators under Dr. Robert Klocke. He is quick to point to other
things under study that also influence the rate of this exchange —
the movement of chloride and hydrogen ions in and out of the blood
cells and substances inside the red cell such as the compound 2, 3diphosphoglyceric acid that influences the way we transport oxygen
and carbondioxide. "The more of it around," he explained, "the
harder it is for oxygen to bind with hemoglobin." In certain acid
states, a complication of lung disease, the exchange of gases may
not be complete, therefore not as efficient upon leaving the lungs.

Dr. Francis Klocke and Dr. Rene Oliveros, a cardiologist from Peru,
are measuring barometric pressure.

58

THE BUFFALO PHYSICIAN

Dr. Wittenberg and Mr. John Curran, electrical technician, are measuring and
recording blood pressure of the animals used in their research.

Through the use of his modified version of continuous flow reaction
apparatus, measurements of these reactions — that are all interre­
lated—can now be made.
In his studies to validate a specific method to measure cardiac
output and to set limits under which it can be used, this investigator
has found that indocyanine green, the most commonly used dye,
takes longer to bind albumin than was previously thought.
But there are also programs dealing with mathematical models
of heart and lung function and the development of new methods
for evaluating various aspects of heart/lung malfunctions. Explained
Dr. Mates, "our group's overall objective is to develop quantifica­
tion descriptions relating the clinical measurements to basic physio­
logical functions." In their attempt to develop a model describing
the fluid mechanics of coronory circulation in the presence of
coronary artery disease, they want to understand what constitutes
a severe obstructing of the coronary artery from a fluid mechanics
point of view and to isolate the factors which could potentially
cause catastrophic events such as myocardial infarctions.
Summed up Dr. Francis Klocke, "we are trying to address our­
selves to the major cardiopulmonary problems with which physicians
are now confronted. This grant is an invaluable mechanism for
allowing us to approach our research on a stable, longterm and,
we hope, creative basis."D
WINTER, 1972

59

Testing the oxygen consumption, efficiency and proficiency of swimmers on the
monitoring platform are Drs. Rennie, diPrampero (visiting professor from Italy),
Leon E. Farhi, Hermann Rahn, all of the physiology department.

Swimming
Analysis

What are the forces that man must overcome when he swims
or moves about in water? Or his mechanical efficiency of locomo­
tion? Or his energy cost in underwater activity? And how do the
stresses imposed on the muscular, respiratory and circulatory sys­
tems in this cold and viscid medium differ from those in our more
natural air environment?
Through the implementation of a new experimental approach,
members of the department of physiology are exploring these ques­
tions with subjects who are keen on knowing the answers — the
SUNYAB swim team.
60

THE BUFFALO PHYSICIAN

A team of investigators under Dr. Donald W. Rennie (professor
of physiology) has long been involved in problems of man in a
water environment, especially his heat balance. In the concentric
submergence basin of the Laboratory of Environmental Physiology
they are now starting a systematic study of locomotion in water,
beginning with swimming on the surface and later going on to
underwater activity.
Explained Dr. Rennie, "while a great deal is known about the
energy cost, mechanical efficiency, and cardiopulmonary response
to walking or running, this is not so in the case of the swimmer.
For no one has determined the actual water resistance or his
"body drag."
A simple method devised by the team that was adapted unique­
ly to the annular pool will allow this determination to be made for
all kinds of surface and underwater swimming techniques. And it
will cover the entire range of swimming velocities.
By coupling this to more conventional methods for measuring
energy metabolism and the mechanics of swimming, the team hopes
to develop a whole new approach to the quantitative analysis of
swimming. In their systematic study of the crawl—a common swim­
ming style—the investigators pace members of the Buffalo swim
team from a movable platform on which equipment is stored for
measuring oxygen consumption and heart rate. This platform also
contains apparatus necessary to determine the "drag" during swim­
ming.
They have postulated that neither "body drag" nor mechanical
efficiency of swimming by itself is sufficient to determine the velocity
that a swimmer can attain. Of crucial importance should be the
ratio of efficiency to drag — "E/D ratio."
Actual measurements bear out the theory that the higher the
ratio, the faster the velocity that a swimmer can attain. The method,
as hoped, has differentiated between good and poor swimmers.
For achieving the highest E/D ratios were the swim team's better
swimmers.
Interestingly, and unexpectedly, women swimmers were found
to have higher E/D ratios than men and theoretically for the same
energy expenditure should achieve higher velocities. That they do
not beat men in top competition is therefore due to the male's abil­
ity to generate more muscular power, thus compensating for his
lower E/D ratio.
Additional evidence for women's higher E/D ratios — their
superior ability to adapt to an aquatic environment — is previous
work done on the diving women of Korea and Japan. They estab­
lished a superior ability to withstand the cold stress of water.
And for the layman there are practical applications of these
experiments. His ability to enjoy water sports may be enhanced by
calculating in a quantitative way how he can improve his technique.D
WINTER, 1972

61

Dave Sexton, a sophomore, talks over
an experiment with William H. Sanlord, III, UB swimming coach.

95 Faculty Promotions
The following 95 members of the Medical
School faculty received promotions effective
July 1, 1972.

livan (medicine); James F. Upson (surgery);
Walter T. Zimdahl (medicine).

Promotions to Professor: Doctors Edson X. Al­
buquerque (pharmacology); Stanley Cohen
(pathology); Andrew Gage (surgery); Franz E.
Glasauer (surgery-neurosurgery); Joseph Kite
(microbiology); Carel J. van Oss (microbiology).

Doctors Frank Bolgan (surgery); George C.
Brady (medicine); John L. Butsch (surgery);
William A. Carnahan (forensic psychiatry in de­
partment of psychiatry); Tai Soon Choi (pedi­
atrics); Michael E. Cohen (neurology); Bernard
A. Daly (anesthesiology); Allie H. Freeman
(psychiatry); Albert A. Gartner (anesthesiol­
ogy); Ikram Haque (surgery-neurosurgery);
Frederick Helm (medicine-dermatology); Stev­
en Joyce (surgery-orthopedic surgery); Michael
A. Jurca (surgery-otolaryngology); Duck Jin Kim
(surgery-otolaryngology); Joseph W. Kramarczyk (anesthesiology); Herbert Lee (anesthes­
iology); Desmond Moleski (psychiatry); Oscar
R. Oberkircher (pediatrics); Marjorie M. Plumb
(psychology in department of psychiatry);
Susana S. Reyes (psychiatry); Ravinder Tandon
(medicine); William Walsh (medicine-psychia­
try); Donald J. Yung (surgery-ophthalmology).

Promotions to Associate Professor: Doctors C.
John Abeyounis (microbiology); James Ed­
ward Allen (surgery); Carl J. Bentzel (medicine);
Constantine Chlouverakis (medicine); Thomas
D. Flanagan (microbiology); C. A. Glomski
(anatomy); Kyoichi Kant (microbiology); Leon­
ard Katz (medicine); Frederick C. Kauffman
(pharmacology); Luis L. Mosovich (pediatrics);
Robert W. Noble (medicine); Pearay L. Ogra
(pediatrics); Reinhold E. Schlagenhauff (neurol­
ogy); S. Subramanian (surgery); Zebulon C.
Taintor (psychiatry); Stephen Wittenberg (med­
icine).
Promotions to Assistant Professor: Doctors Jon
O. Flom (pediatrics); Eva Lotzova (pathology);
Murray W. Stinson (microbiology).
Promotion to Clinical Professor: Doctor
liam F. Lipp (medicine).
Promotions

to

Clinical

Associate

Wil­

Professor:

Doctors Karl Balthasar (neurology); Lee L. Ber­
nards (pathology in department of medicine);
Francis J. Clifford (anatomy); Donald Ehrenreich (neurology); Sattar Farzan (medicine);
Irwin Friedman (medicine); Emma K. Harrod
(pediatrics), also Research Instructor in medi­
cine; Jack Herrmann (surgery); William Hildebrand (surgery-otolaryngology); Clair M. Hossenlopp (psychiatry); William R. Kinkel (neurol­
ogy); Salvatorq LaTona (medicine); Warren R.
Montgomery (medicine); Cornelius J. O'Connell (medicine); Joseph R. O'Connor (medi­
cine-psychiatry); Harold K. Palanker (surgery);
Theodore Papademetriou (surgery-orthopedic
surgery); Robert E. Reisman (medicine); Gloria
L. Roblin (psychology in department of psychi­
atry); Robert Spier (surgery); Michael A. Sul­
62

Promotions

to

Clinical

Assistant

Professor:

Promotion to Research Professor: Doctor Ger­
ald P. Murphy (surgery-urology).
Promotions to Research Associate Professor:
Doctors Pier Luigi Bigazzi (microbiology), Wil­
liam H. Murphey (pediatrics); Thomas Provost
(medicine).
Promotions to Clinical Associate: Doctors Gas­
pare A. Alfano (neurology); Anthony Aquilina
(medicine); Henry E. Black (medicine); Charles
D. Bull (medicine); Cyril S. Bodnar (surgeryotolaryngology); Barry Herman (medicine);
Sanford R. Hoffman (surgery-otolaryngology);
Courtland S. Jones, Jr. (surgery-otolaryngology);
Fred Lieberman (medicine); A. Charles Massaro
(medicine); John J. McMahon (medicine); Lo­
renzo T.
Teruel
(surgery-otolaryngology);
Joseph C. Tutton (neurology); Ernesto G. Zingapan (surgery-otolaryngology); Robert J. Zwirecki (neurology).
Promotions to Clinical Instructor: Doctors Juan
Garcia (psychiatry); Leo Michalek (surgery);
Lionel Sifontes (medicine); Sara R. Sirkin (sur­
gery-ophthalmology).•
THE BUFFALO PHYSICIAN

The 1915 Class
Two 1915 Medical School graduates are new
officers in the Association of Past Presidents of
the Medical Society of the County of Erie. Dr.
Carlton E. Wertz was named president and Dr.
Herbert E. Wells is the new secretary. Dr.
Wertz was president of the society in 1939 and
Dr. Wells in 1940.D
The Classes of the 1920's

Dr. Marvin A. Block, M'25, received the
American Medical Society on Alcoholism's
medal of achievement, the organization's high­
est award, during the group's third annual
meeting in Atlanta. In making the presentation,
Dr. Stanley E. Gitlow, society president, cited
Dr. Block's 25 years of service in the field of
alcoholism and his role in gaining the AMA's
recognition of alcoholism as a disease. Dr.
Block has played significant roles in the Na­
tional Council on Alcoholism, the Alcohol and
Drug Problems Association of North America
and in the American Medical Society on Alco­
holism. He has written over 50 professional
articles and books, treated thousands of pa­
tients and has helped educate thousands of
other people about alcoholism throughout the
world. Dr. Block is a clinical assistant professor
of medicine at the Medical School.•

It was a "father-son" affair at the spring commencement.
The Distinguished Professor of Anatomy Dr. O. P. Jones
hoods his son, O. P. Jones, 3rd, who received his Ph.D. in
English. The son is on the faculty of Ohio Wesleyan
University, Delaware, Ohio.

The Classes of the 1930's

Dr. Joseph D. Godfrey, M'31, suggests the
elimination of the position of pitcher in Little
League Baseball. He told the American Acad­
emy of Orthopedic Surgeons meeting in Eu­
gene, Oregon that the risks of elbow joint
changes were severe enough to warrant the
step.
"No kid of mine would ever pitch little
league baseball. The possibilities of sustaining
permanent elbow restrictions of motion or an
abnormal area at the elbow may definitely stem
from throwing overhand at an early age. I
would recommend that methods such as a
pitching machine, a tee as in golf, or a toss-up
mechanism be used to set the ball up to hit in
both practice session and games."
Dr. Godfrey is chief of orthopedic surgery at
Children's Hospital and clinical professor of
surgery (orthopedic) at the Medical School. He
is also team physician for the Buffalo Bills, pro­
fessional football team.D
Dr. Carl T. Javert, M'32, an obstetrician-gyne­
cologist, is listed in "Who's Who in America."
(1971) He recently joined Hubbard Regional
Hospital, Webster, Massachusetts to direct and
develop the obstetrical and gynecological service.D
Dr. Albert John Magnus, M'35, has been in
industrial medicine for 15 years. He writes that
he has been in poor health for the past 2V2
years. His address is 3116 Culver Road, Roch­
ester, New York.D
Dr. Elizabeth Pierce Olmsted, M'39, was one
of five University women to receive a special
citation from the UB Alumni Association and
the UB Community Advisory Council for
achieving distinction in her career through in­
volvement in community activities. Dr. Olm­
sted is chief of staff of the ophthalmology de­
partment at Deaconess Hospital and a clinical
instructor in surgery (ophthalmology) at the
Medical School. She was president of the Wettlaufer Clinic staff before it merged with Dea­
coness. She is director of the Buffalo Associa­
tion for the Blind and is a consultant with the
National Society for the Prevention of Blind-

Dr. Milford C. Maloney, M'53, was named
full-time chairman of the department of medi­
cine at Mercy Hospital June 1. He is a clinical
assistant professor of medicine at the Medical
School.•

The Classes of the 1940's

Dr. Harold ). Palanker, M'40, clinical associate
professor of surgery, is a member of various
county, state and national societies in his spe­
cialty. He lives at 66 Ruskin Road, Eggertsville,
New York.D
Dr. Richard Ament, M'42, has been elected
to the Board of Governors of the American
College of Anesthesiologists. He is a clinical
professor of anesthesiology at the University
and attending anesthesiologist at the Buffalo
General Hospital. Dr. Ament attended the 5th
World Congress of Anesthesiologists in Kyoto,
Japan in September. He was one of 11 dele­
gates.•
Dr. Lawrence H. Golden, M'46, is co-operat­
ing with the School of Pharmacy in setting up
one of the nation's first clinical pharmacoki­
netics laboratories at the Millard Fillmore Hos­
pital. Dr. Golden is chief of medicine at the
hospital and a clinical associate professor of
medicine. Dr. William Jusko, assistant profes­
sor of pharmaceutics at the University, is super­
visor of the new lab that enables physicians
to regulate and adjust their patients' medication
according to their individual drug responses.D
Dr. Raymond J. Trudnowski, M'46, has been
named chief of the department of anesthesiol­
ogy at Roswell Park Memorial Institute. He also
received his dental degree from the University.
After 14 years as an oral and maxillofacial
surgeon, Dr. Trudnowski turned to anesthesia.
He trained in that specialty at Buffalo General
and Children's Hospitals. He is the author of
several publications.•

Dr. Michel A. Glucksman, M'54, is a urologist
practicing in Brunswick, Georgia. He is living
at 152 Fairway Oaks Drive.•
Donald R. Hauler, M'57, was recently pro­
moted to Captain, Medical Corps, U.S.N. While
assigned duty as Senior Medical Officer in USS
ENTERPRISE CVAN-65 (1969-1972), he was
awarded the Navy Commendation Medal, Meri­
torious Unit Citation and Navy Expeditionary
Medal. Captain Hauler's home address is 912
Kane Circle, Walnut Creek, California.•
Dr. Ann Tracy, M'58, is a clinical assistant
professor of pediatrics and psychiatry at the
Medical School. She also works with children
at the Children's Psychiatric Center at the West
Seneca State School. Dr. Tracy entered Medi­
cal School in 1944 and completed three years
before getting married. She then took a leave
to raise her family (two sons) and returned in
1957 to complete her fourth year in Medical
School. She interned at Children's Hospital and
took her residency at Buffalo State Hospital.
She did other post-graduate work at Harvard
Medical School and Children's Hospital, Wash­
ington, D. C.D
Dr. Robert A. Brenner, M'59, clinical instruc­
tor of orthopaedic surgery, Upstate Medical
Center, Syracuse, New York, is planning to
work overseas throughout the next school year
as volunteer overseas missionary at McCormick
Hospital and McKean Leprosarium in Chiengmai, Thailand.•

The Classes of the 1960's
The Classes of the 1950's

Dr. Joseph M. Mattimore, M'50, is the new
president of the Buffalo Allergy Society. He is
a clinical associate professor at the University
and a Fellow of the American Academy of
Pediatrics. He is also chief of pediatrics at
Mercy Hospital.•
64

Dr. William E. Abramson, M'60, is a senior
staff psychiatrist at the Sheppard and Enoch
Pratt Hospital, Towson, Maryland. He was re­
cently appointed director of the Comprehen­
sive Drug Abuse Program at the hospital for
the State of Maryland's Drug Abuse Adminis­
tration. Dr. Abramson lives at 8281 Marcie
Dr., Baltimore.D
THE BUFFALO PHYSICIAN

Dr. Harris C. Faigel, M'60, is author of an
article "Childhood

Mortality

is

No Way to

In May a 1968 Medical School graduate will
return to the community that helped him with

Measure a Nation's Health" that appeared in

his medical education expenses.

the April, 1972 issue of Clinical Pediatrics. Dr.

Paul K. M u r p h y c o m p l e t e s his naval service h e

Faigel lives at 1 5 Beaver Hill Lane, New Haven,

will return to the Perry Medical Center, New

Conn.D

York with

Dr. James R. Blake, M'63, was married to Miss
Marilyn Amber Linnemann in May in Beverly
Hills, California where Dr. Blake has a private
practice.D

When

his wife and three children.

Dr.

Dr.

Murphy took both his internship and residency
at the Millard Fillmore Hospital.•

Dr. Lawrence J. Schwartz, M'68, is Chief Resi­
dent in Ophthalmology, Pacific Medical Center,
San Francisco. He was chief investigator on an

Dr. Ronald S. Mukamal, M'64, has separated
from the U.S.A.F. and is now in private practice
of general surgery in Whiteville, North Caro­
lina. His address is 707 North Thompson St.D

Dr. August J. D'Alessandro, M'65, a psychi­
atrist employed by the state of Connecticut, is
co-ordinator of psychiatric services and med­
ical services, Security Treatment Center, Middletown, Conn. He is also consultant psy­
chiatrist for the Connecticut Youth Services
Commission. He has recently had articles pub­
lished in Hospital Physician, Resident Physician,
and Psychiatric Quarterly.[J

article published in June 72 AMA ARCHIVES OF
OPHTHALMOLOGY, entitled "Electrophysio­
logic and Fluorescein Studies in Vitelliform Ma­
cular Degeneration." He lives at 2090 Green
Street, San Francisco.•

Dr. James A. Dunlop, M'69, is the new direc­
tor of maternal and child health at the Erie
County Department of Health. He is also a
clinical assistant instructor in pediatrics.D

Dr. Bruce S. Rabin, M'69, a former member
of The Center for Immunology (1970-72), is
now (July) Assistant Professor of Pathology at
the University of Pittsburgh.

Dr. Donald J. Waldowski, M'65, was recently
appointed Director of Pediatric Education at
Spartanburg

General

Hospital,

Spartanburg,

South Carolina (affiliated with Medical Univer­
sity of South Carolina). He lives at 116 Duval

He will establish

a division of Diagnostic Immunopathology
there as its Associate Director. Dr. Rabin has
authored 18 papers in the field of immunology
and lives at 1235 Malvern Avenue, Pittsburgh.•

Drive.•

The Classes of the 1970's
Dr. Jesse M. Hilsen, M'66, is on the faculty
of Mt. Sinai Hospital and Medical Center (New
York City) as research psychiatrist after com­
pleting an adult and child psychology residency

Dr. Neil Garroway, M'70, is now at the Vanderbilt University School of Medicine, Nash­
ville, Tennessee.•

there. He is consultant to Family Court of New
York City; U. S. Public Health Service; Night­

Dr. Jan Martin Novak, M'70, is now (as of

ingale Bamford School; psychiatrist for U. S.

July 1st) an Associate Resident in Medicine at

Air Force Reserve, as well as being in private

Strong Memorial Hospital in Rochester, New

practice at 35 East 85th Street, New York City.D

York.

He was formerly Assistant Resident in

Medicine at Bronx Municipal Hospital Center,
Dr. David Wallack, M'66, is a clinical instruc­
tor in medicine, University of Colorado Medical
School.

Albert Einstein College of Medicine. His ad­
dress is 77 Clintwood Court, Rochester.•

He and his wife, Bonnie, announce

the birth of their first child, daughter Adriana,

Dr. D e n n i s J. Rosen, M'71, of 3 Ellsworth

in April. T h e Wallacks live a t 1 0 9 1 E. P a n a m a

Park, Cambridge, Massachusetts, is in pediatrics
residency at Boston City.Q

Drive, Littleton, Colorado.•

WINTER, 1972

65

People

Dr. Vincent J. Capraro, clinical professor of
gynecology-obstetrics at the School of Medi­
cine, has been awarded the Diploma of Honor
by the International Federation of Infantile and
Juvenile Gynecology "in recognition of his
many contributions in the field of adolescent
and pediatric gynecology."
The award was presented at its First Sym­
posium held June 23-25 at the University of
Bordeaux, France where Dr. Capraro presented
four papers (gynecologic examination in chil­
dren and adolescents; management of anovula­
tion; breast problems in children and adoles­
cents; volvovaginoplasty—A new technique for
vaginal agenesis).
The Buffalo-educated physician (MD 1945
UB; internship and residency at E. J. Meyer
Memorial Hospital 1945-46 and '48-51) joined
the faculty in 1951. He is a Diplomate of the
American Board of Obstetrics/Gynecology and
a Fellow of the International College of Sur­
geons, American College of Surgeons, and the
American College of Obstetrics/Gynecology.
Dr. Capraro is also chief of the division of
adolescent and pediatric gynecology at Chil­
dren's Hospital.•
Dr. Jean A. Cortner has received a special
fellowship from the National Institutes of
Health to spend a year doing research in the
Department of Human Genetics and Biometry,
Galton Laboratory, University College, London,
England. He is taking a year's leave of absence
beginning Sept. 1 from his position as professor
and chairman of the Department of pediatrics
at the Medical School. He is also pediatricianin-chief at Children's Hospital. His wife and
three children will accompany him to Eng­
land.•
66

Dr. Daniel Rakowski, clinical assistant pro­
fessor of psychiatry, has been named acting
head of the department of psychiatry at the
E. J. Meyer Memorial Hospital. He has been
clinical director of the department. Dr. Jimmie
Holland, associate professor of psychiatry, has
resigned to accompany her husband, Dr. James
F. Holland, to Moscow, where he will be
the first chief medical liaison officer between
the National Cancer Institute and the Soviet
Union. He was a research professor of medi­
cine at the Medical School and chief of medi­
cine at Roswell Park Memorial Institute. He
has taken a leave of absence from both posi­
tions.
As a member of the National Panel of Con­
sultants on the Conquest of Cancer, Dr. Hol­
land was a principal architect of the National
Cancer Act of 1971. In Moscow he will study
Russian cancer research programs to learn what
is being done there and to inform the Russian
scientists of progress in America. His wife will
be a special consultant in Russia for the Na­
tional Institute of Mental Health. Enroute to
Russia the Hollands stopped in Israel where
Dr. James Holland gave the Dameshek Mem­
orial Lecture to the Israel Society of Hematology.D
Five Medical School faculty members are
serving on the advisory board of the abortion
clinic of the Erie Medical Center at 50 High
Street. They are: Drs. Jack Lippes, associate
professor of gynecology-obstetrics; Dean R.
Goplerud, assistant professor of gynecologyobstetrics; Harold P. Graser, clinical assistant
professor of psychiatry; Murray S. Howland,
clinical professor of medicine; and Robert J.
Patterson, clinical instructor in gynecology-ob­
stetrics. Also serving on the board is Edythe
Goetz, intake supervisor and co-ordinator,
Family Service Society and Clarice S. Lechner,
R.N., associate professor, maternal health nurs­
ing, School of Nursing at the University.D

THE BUFFALO PHYSICIAN

of aging. The Center for Immunology at the
Medical School will be involved in the project.
A clinical associate professor of pediatrics
at the Medical School is expanding t h e lead
poisoning testing program for inner city chil­
d r e n . D r . E m m a K. H a r r o d , E r i e C o u n t y D e p u t y
Health Commissioner for maternal and child
health, said the $225,000 grant from the Health
Services and Mental Health Administration will
be used to test about 10,000 children ages 1-5.
The grant money will also be used to increase
public education on dangers of lead poisoning
and increase follow-up assistance to families of
children suffering from the ailment. It is also
hoped that within five years most of the leadcontent paint will be removed from many of
the city's older homes.D

The man who designs the covers for THE
BUFFALO PHYSICIAN is Richard Macakanja,
health sciences graphic artist. His cover design
(reproduced in miniature) won an "excellence
in design award" and placed second in the an­
nual Inhouse Publications Contest sponsored
by Industrial Art Methods. The Texaco Star
magazine won first place. Mr. Macakanja's
cover design depicted the 1971 Spring Clinical
Days. The photos were taken by Hugo Unger,
health sciences photographer.
Mr. Macakanja has been on the Health Sci­
ences staff for six years. He received his BFA
degree from the University in 1960 and expects
to receive his MFA in January, 1 9 7 3 . •

Four alumni are newly elected officers of the
Western New York Society of Internal Medi­
cine. Dr. William Breen, M'55, is the new presi­
dent and Dr. Joseph Zizzi, M'58, is the new first
vice president. The new treasurer is Dr. Edward
Craber, M'60, and Dr. James Kanski, M'60, is
secretary. Dr. Louis Kramer, a clinical associate
in medicine at the Medical School, is the sec­
ond vice president.Q

Dr. Morton Rothstein, professor of biology
at the University, received a $1 million 5-year
grant from the National Institute of Child Care
and Human Development to study the causes
WINTER, 1972

Dr. Louis Bakay, professor of surgery (neuro­
surgery) at the Medical School and who heads
the division of neurosurgery at the Buffalo
G e n e r a l , C h i l d r e n ' s a n d E. J. M e y e r M e m o r i a l
H o s p i t a l s g a v e t h e p r e s t i g i o u s D r . L. P . M o u s seau Memorial Lecture at the Edmonton Gener­
al Hospital in October on "The Blood-Brain
Barrier: Its Theory and Clinic Utilization.
Dr. John W. Boylan, professor of medicine
and physiology at the Medical School is editor
of the 1971 issue of Mount Desert Island
Biological Laboratory, Salisbury Cove, Maine.
In the 111-page bulletin are research reports
of 31 investigative groups from 18 states and
three other countries who worked at the in­
dependent marine biological station during
the summer of 1971.•
Dr. Michael D. Garrick, assistant professor of
biochemistry, participated in two symposiums
in Australia and New Zealand in May. His ad­
dress, "Hemoglobins and Evolution" was given
at the University of Otago, Dunedin, New Zea­
land. The paper he gave in Sydney was "The
Anaemia-Induced Reversible Switch from Hae­
moglobin A to Haemoglobin C in Goats and
Sheep: The Two Haemoglobins are present in
the Same Cell During the Changeover." He also
gave a talk at the National Institutes of Health
on "Hemoglobin Switching in Goats and
Sheep."•
67

People

Dr. Franz E. Glasauer, professor of neuro­
surgery at the University, was recently elected a
charter member of the International Society
for Pediatric Neurosurgery (May, 1972). He has
been the participating neurosurgeon at the
Birth Defects Clinic (Children's Hospital) since
its establishment in 1966. Many of his publica­
tions deal with the diagnosis, treatment, or
other problems in pediatric neurosurgery. Dr.
Glasauer is a 1955 graduate of the University
of Heidelberg (Germany) Medical School.•

Dr. Cohen

Dr. Maimon Cohen, associate professor of
genetics and head of the division of cytogenet­
ics at Children's Hospital, has left to establish
and head the first department of human ge­
netics at Hadassah Hebrew University Medical
Center, Jerusalem. He had been on the Uni­
versity staff since 1965.•

Dr. Carel J. van Oss, associate professor of
microbiology, is involved in space research. An
experiment on "The Electrophoresis of Latex
Particles at Zero Gravity" was done in Apollo
16 on its way to the Moon, during the weight­
less period. The experimental equipment was
left on the Moon. However, the photographs
which were taken every 20 seconds during the
experiment and the Astronauts' tape were re­
turned to Earth for analysis. This is the first
of a series of experiments aiming at the pre­
parative electrophoretic separation of living
cells that will be continued on Apollo 17 and
Skylab 1. Dr. van Oss is a member of the Uni­
versities Space Research Association Commit­
tee on Separation Methods.•

Dr. Jack Herrmann, clinical associate profes­
sor of surgery, scored a hole-in-one at the
Westwood Country Club in August. He used a
4-wood to ace the 175-yard third hole. Dr.
Herrmann is on the Buffalo General Hospital
medical staff.D

Dr. Richard G. Cooper is the new president
of the Erie County Unit of the American Cancer
Society. Dr. Cooper is a clinical associate pro­
fessor of medicine. Dr. Alfred M. Stein, M'58,
is the vice president and president elect. He is
a clinical associate professor of medicine.D
68

Drs. John Dower, professor of community
pediatrics and James Markello, assistant pro­
fessor of pediatrics, (both on the staff of Chil­
dren's Hospital) are teaching nursing students
in two new programs that will train nursing
clinicians, practitioners and teachers in the
field of child health nursing. The two graduate
programs, offered for the first time, received
federal grants totaling $591,148.•
Two Medical School faculty members have
been named Fellows in the American College
of Cardiology, Dr. S. Subramanian is a clini­
cal associate professor of surgery, a pediatric
cardiac surgeon, and chief of the division of
cardiovascular surgery at Children's Hospital.
Dr. Walter T. Zimdahl, a cardiologist, is a clini­
cal associate professor of medicine and acting
chief of medicine at Deaconess Hospital.•
Dr. Herbert A. Hauptman, research professor
of biophysical sciences, has been named vice
president and research-executive director of
the Medical Foundation of Buffalo. He is inter­
nationally known for his work in determining
the crystal structure of steroid hormones and
other biological substances.•
Dr. Guyon P. Mersereau, clinical assistant
professor of psychiatry, is the new director of
the Erie County Forensic Psychiatry Service. He
has been acting director since February, 1970.D
A 635-page book based on a study of the in­
cidence of long-term childhood illnesses in Erie
County between 1946 and 1961 has been pub­
lished by the University of Pittsburgh Press.
Authors are Dr. Harry A. Sultz, professor of
social and preventive medicine at the Medical
School; Dr. Edward R. Schlesinger, formerly as­
sistant commissioner for special health services
in the State Health Department; Dr. William
Mosher, Erie County Health Commissioner; and
Joseph G. Feldman, former clinical instructor
in social and preventive medicine at the Med­
ical School.•
Three Medical School faculty members are
new Fellows of the American College of Physi­
cians. They are Drs. Germante Boncaldo, M'57,
clinical instructor in medicine; Thomas D.
THE BUFFALO PHYSICIAN

Doeblin, M'59, clinical assistant professor of

Dr. S. Mouchly Small, professor and chair­

medicine; and )ohn A. Edwards, research as­

man of the Department of Psychiatry at the

sistant professor of medicine.•

School of
pointed to

Medicine has recently been
the National Board of

ap­

Medical

Examiners, Part III Committee for Patient Man­
The Memorial Medical Center at Niagara

agement Problems. Dr. Small is the only psy­

Falls, N. Y. has received a $748,154 federal grant

chiatrist on this Committee.

for the community mental health center. Dr.

also serves on the Written Examination Com­

Milton Robinson, M'51, psychiatric

In addition, he

director,

mittee of the American Board of Psychiatry and

said the money would be used to expand serv­

Neurology and on the American Psychiatric
Association's Self-Assessment Test Committee

ices—especially prevention services at all levels
of community involvement. The 5th, 6th and

for Patient Management Problems. This puts

7th floors of the Memorial Medical Center are

him in the unique position of serving on the

used for the mental health center.D

three major examination committees in Ameri­
can Psychiatry.

There aren't many women forensic pathol­
ogists in the United States. Dr. Judith Lehotay,
a clinical assistant professor of pathology at the
Medical School, is one. She describes herself
as a "medical detective" or a liaison between
medicine and the law. She is in the Erie County
Medical Examiners' Office. Her profession re­
quires examination of bodies of persons who
died through violence (murder, suicide or acci­
dent) and those not attended by a physician

With Professor Peter F. Regan of the Depart­
ment of Psychiatry and Dr. Hugh Carmichael
of

the

American

Psychiatric

Association

in

Washington, D. C. as co-authors, he published
a book this year on "Lifetime Learning for
Psychiatrists." This book includes the impor­
tance of self-assessment examinations and ob­
jective-type examinations for an on-going eval­
uation of clinical knowledge, skills, and com­
petence for psychiatrists.•

shortly before death. Dr. Lehotay is a native
of Hungary.

She and her husband came to

Buffalo in 1957.

She interned at Children's

Hospital and took her residency at Sisters'
Hospital.•

The new president of the Erie County Medi­
cal Society is Dr. Leonard Berman, a 1946 grad­
uate of Wayne State University, Detroit. He is
not a UB graduate as was reported in the Fall

Dr. Walter J. Gannon, M'44, is the new Erie
County Medical Examiner. The family physician
replaces Dr. Michael A. Jurca, M'42, who re­
signed to take a full time position on the
Medical School faculty.

Another Buffalo sur­

issue of The Buffalo Physician. Dr. Berman, a
clinical associate professor of surgery at the
Medical School, spent two weeks last summer
visiting hospitals and medical centers in Japan,
Thailand and Hong Kong.n

geon, Dr. Ernest Fernandez, was also appointed
medical examiner for the County. He is a native
of Puerto Rico and received his M.D. from the
University of Chicago.Q

man of the division of orthopaedic surgery at
the Medical School and the E. J. Meyer Me­

While on sabbatical leave in London the last
year, Dr. Mitchell I. Rubin wrote a book on
pediatric nephrology. From 1945 to 1967 Dr.
Rubin was chairman of

Dr. Eugene R. Mindell, professor and chair­

morial Hospital, is the new president of the
Orthopaedic Research Society. He will preside
at the next annual meeting in January at Las
Vegas, Nevada.•

the department of

pediatrics at the University and pediatrician-inchief at Children's Hospital. He and Mrs. Rubin
will make their home in Charleston, S. C. where

Dr. Helen M. Ranney, professor of medicine,

he will be associated with the Medical College

is president-elect of the American Society of
Hematology.D

of South Carolina.•

WINTER, 1972

69

In
Memoriam

Dr. Edward Cook, M'33, was killed October
10 when his auto failed to make the turn onto
Main Street in Buffalo and struck a light pole.
He was a specialist in internal medicine and
was a clinical associate in medicine on the fac­
ulty for 34 years. Dr. Cook also served on the
board of internal medicine at the Buffalo Gen­
eral Hospital. He was a lieutenant colonel in
the Army Medical Corps during World War
II.•

Dr. William W. Kunz, M'53, died September
8 in Buffalo General Hospital after a five month
illness. The 45-year-old specialist in internal
medicine was a member of the staff of the
Brooks Memorial Hospital, Dunkirk where he
headed the department of electrocardiography.
He was a member and past president of the
Chautauqua County Medical Society, a Fellow
of the American College of Physicians, a mem­
ber of the Medical Society of the State of New
York, a Diplomate, American Board of In­
ternal Medicine, the American Society of In­
ternal Medicine, and the AMA. He was also
active in the Narcotics Guidance Council at
Dunkirk.•

)r. William C. Werkheiser, research associ­
ate professor of biochemistry and pharmacol­
ogy, died suddenly September 1. He was also
a Roswell Park Memorial Institute cancer re­
searcher. He joined the Roswell Park staff as
senior cancer research scientist in the experi­
mental therapeutics department in 1956 and
became associate cancer research scientist in
1961. The 52-year-old Dr. Werkheiser had been
on the Medical School faculty for 12 years. He
received his bachelor's degree from Brown
University and his master's and doctorate in
biochemistry from the University of Southern
California. He was a pre-doctoral fellow of the
American Cancer Society and studied at Oxford
University as a post-doctoral fellow of the
National Cancer Institute.•
l-Or. Robert F. Sullivan, M'58, died October 2
in Mercy Hospital after a long illness. He was
53 years old. He had been a general practi­
tioner for 28 years and a member of the Mercy
Hospital medical staff. Dr. Sullivan was active
in sports. He pitched for Canisius College and
the Buffalo Municipal Baseball Feague. He was
also active in several professional organiza­
tions^

Dr. Winzler Dies Suddenly
Dr. Richard J. Winzler, professor in the de­
partment of chemistry at The Florida State Uni­
versity, died suddenly at his home in Tallahas­
see, Florida September 27. The biochemist had
been chairman of the biochemistry department
at the UB Medical School from 1965 to August
1969.

Dr. Winzler

rx

Dr. Winzler, born in San Francisco in Sep­
tember 1914 received both his Bachelor of Sci­
ence and Doctor of Philosophy degrees from
Stanford University (1936 and 1938 respective­
ly). He was a Sterling Fellow at Yale and a
National Research Council Fellow in Stock­
holm, Sweden (1939-40) and at Cornell Uni­
versity (1940-41). Dr. Winzler was associated
with the National Cancer Institute in Bethesda,
Maryland before accepting an assistant profes­
sorship at the University of Southern California.
From 1952 to 1965 he was professor and head
at the University of Illinois, department of bio­
chemistry in Chicago. He came to Buffalo in
1965 to head the department of biochemistry
70

at the University until he moved to Tallahassee
in 1969.
Among other honors Dr. Winzler was a Visit­
ing Professor at the University of Wisconsin in
1941, a Commonwealth Fellow at the Univer­
sity of Freiburg, Germany in 1958 and a con­
sultant in medical education at the University
of Chiengmai, Thailand in 1962. Author of over
175 articles in the fields of glycoprotein chem­
istry, biochemistry of cancer tissues, and mem­
brane structure, Dr. Winzler has been editor
for two journals, Cancer Research and Proceed­
ings of the Society for Experimental Biology and
Medicine. He had been actively associated with
work of the American Cancer Society and of
the National Institutes of Health.
The Dr. Richard J. Winzler Memorial Fund
has been established. Contributions should be
sent to Dr. Earl Frieden, department of chem­
istry, Florida State University, Tallahassee,
Florida, 32306.•
THE BUFFALO PHYSICIAN

)r. Cathryn Jones died September 28. She
was the wife of Dr. Oliver P. Jones, retired
chairman and distinguished professor of anat­
omy at the Medical School. She had been as­
sistant to the medical director of the Buffalo
Red Cross for the past 15 years. She was a
1935 graduate of the University of Minnesota
Medical School. She came to Buffalo with her
husband in 1937. The couple had four children.
She served as a physician with the Red Cross
blood program in 1942-43. In 1952 she re­
turned to the Red Cross. In 1941 she was an
instructor for medical technologists at the Mil­
lard Fillmore Hospital.•
Dr. Edward Healy, M'39, died September 26.
The 59-year-old family physician was chairman
of the Emergency Room Associates at Sister's
Hospital, a medical program that he started.
He was also the physician to the Sisters at
Mount St. Joseph Convent. In 1969 Dr. Healy
received the Msgr. Francis J. O'Connor Award
for 25 years' service to the children of St. Mary's
School for the Deaf. Dr. Healy started practic­
ing in Buffalo in 1945 after being discharged
from the Army. The Major served aboard a
troop ship for four years as a surgeon. He was
active in several professional organizations.•
Dr. Michael F. Mogavero, M'39, died Sep­
tember 18 in Millard Fillmore Hospital after
suffering a heart attack at his home. The 60year-old ophthalmologist retired in 1970 after
a 31-year career. He began his career as a gen­
eral practitioner and became an eye specialist
after completing training at the Harvard Medi­
cal School in ophthalmology and eye surgery.
He served on the medical staffs at Columbus,
Sisters and Millard Fillmore Hospitals and at the
Wettlaufer Clinic. Dr. Mogavero was active in
several local, state and national professional
organizations-^

/

Dr. Stanley A. Weglikowski, M'33, died Sep­
tember 23 in Buffalo General Hospital. The 61year-old general practitioner was affiliated with
Mercy Hospital. He was active in several pro­
fessional organizations.•
Dr. Rose R. Donk, M'11, 215 Church Street,
Newark, N. J. died August 4, according to the
Lincoln Rochester Trust Company, who is
handling her estate.Q
WINTER, 1972

Dr. Douglas P. Arnold, M'08, died July 26
after a long illness. The 87-year-old man was
hailed by his colleagues as the one who
brought modern pediatrics to Buffalo. He was
head of the pediatrics department at three hos­
pitals — Children's, Buffalo General and Millard
Fillmore. He was a 60-year staff member at
Children's and continued as a consultant mem­
ber following his retirement in 1963. He was
also in charge of the Infant Welfare Clinic of
the Buffalo Health Department for nearly 30
years.
Dr. Arnold was on the Medical School faculty
for 15 years, retiring in 1950 as a clinical pro­
fessor of pediatrics (emeritus). When he re­
tired a lecture series was established in his
honor. The Douglas P. Arnold Lecture brings
an outstanding doctor to Buffalo annually to
discuss some special field of medicine at Chil­
dren's Hospital.
He began his Buffalo practice in 1914 and his
method for replacement transfusions in Rhnegative babies earned him worldwide ac­
claim in medical circles. He was the first physi­
cian to perform that procedure in the Buffalo
area.
Dr. Arnold interned at the Buffalo General
Hospital and took his residency at Harvard. He
did postgraduate study in Berlin and Munich.
He was a member and past president of the
Canadian Society for the Study of Diseases of
Children. He was also a Diplomate of the
American Board of Pediatrics and was active in
several local, state and national professional
organizations-^
/

Dr. Richard A. Bahn, M'52, died July 4 at
his home in Oxford, N. Y. The 45-year-old
surgeon had been in poor health for more than
one year, but had continued to practice until
five weeks before he died. Dr. Bahn spent
seven years as an intern and resident in surgery
at the E. J. Meyer Memorial Hospital and re­
turned to the hospital to practice in 1971. From
1959 to 1963 he was in Harlan, Ky. where he
practiced in the United Mineworkers Hospital.
When the hospital was sold he returned to
New York State and opened a private practice
in Norwich where he was on the staff of the
Chenango County Memorial Hospital. One of
his brothers, Dr. Robert C. Bahn, is a 1947
Medical School graduate and a member of the
Mayo Clinic Staff, Rochester, Minnesota.•
71

Cruise Carnival in Cabin Category
from $299 to $499

Departing from Niagara Falls, N. Y.
on December 30, 1972

Here's what's included:

Caribbean Cruise Carnival to
• San Juan, Puerto Rico; St. Marten; St. Thomas,

• Round trip jet flight to Miami

Virgin Islands; Nassau, the Bahamas.
This cruise will feature a special scientific program
for physicians and dentists by Mirdza Neiders, D.D.S.,
Professor of Oral Pathology, SUNYAB School of Den­

• Accommodations aboard TSS Mardi Gras
for 7 days with air conditioned staterooms
• Three meals a day

tistry.
• Captain's Cocktail Party
The program will include:
1. Early Cancer Detection

• All transfers and luggage handling

2. Differential Diagnosis of Jaw Lesions

• Host escort throughout

3. Oral Manifestations of Dermatologic Diseases
• Briefings on what to see in each
4. Systemic Diseases with Oral Manifestations
5. Case Presentations
Program fee is an additional $50.00. The cruise with
the scientific session is tax deductible.

port-of-call
For details write or call: Alumni Office, SUNYAB
123 Jewett Parkway
Buffalo, N. Y. 14214
(716) 831-4121

Departing by jet Feb. 16 is the Majorcan Carnival — 8 days & 7 nights for
$359.00. From this Mediterranean Island there is an optional day in Madrid.
Other trips to London and Portugal are in the planning stage.

The General Alumni Board - MORLEY C. TOWNSEND, '45, President; DR. FRANK L. GRAZIANO, D.D.S., '65, President­
elect; GEORGE VOSKERCHIAN, Vice President lor Activities; FRANK NOTARO, '57, Wee President lor Administration;
MRS. PHYLLIS MATHEIS KELLY, '42, Vice President for Alumnae; JAMES J. O'BRIEN, '55, Vice President for Athletics;
ROBERT C. SCHAUS, '53, V/ce President for Constituent Alumni Croups; DR. GIRARD A. GUGINO, D.D.S., '61, Vice
President for Development and Membership; G. HENRY OWEN, '59, Vice President for Public Relations; ERNEST
KIEFER, '55, Treasurer; CHARLES M. FOGEL, '38 and ESTHER K. EVERETT, '52, Members of the Executive Committee; Past
Presidents: DR. EDMOND J. GICEWICZ, M'56; ROBERT E. LIPP, '51; M. ROBERT KOREN, '44; WELLS E. KNIBLOE, '47;
RICHARD C. SHEPARD, '48.
Medical Alumni Association Officers: DRS. JOHN J. O'BRIEN, M'41, President; LAWRENCE H. GOLDEN, M 46, Vice
President; PAUL L. WEINMANN, M'54, Treasurer; LOUIS C. CLOUTIER, M'54, Immediate Past-President; MR. DAVID
K. MICHAEL, M.A. '68, Secretary.
Annual Participating Fund for Medical Education Executive Board for 1971-72 — DRS. MARVIN L. BLOOM, M'43,
President; HARRY G. LaFORGE, M'34, First Vice-President; KENNETH H. ECKHERT, SR., M'35, Second Vice-President;
KEVIN M. O'GORMAN, M'43, Treasurer; DONALD HALL, M'41, Secretary; MAX CHEPLOVE, M'26, Immediate PastPresident.

72

THE BUFFALO PHYSICIAN

A MESSAGE FROM
J O H N J. O ' B R I E N , M ' 4 1
PRESIDENT
MEDICAL ALUMNI ASSOCIATION

The University of Buffalo Medical Alumni Association needs your dues contribution more
than ever before. It helps provide much needed School of Medicine-community interplay,
such as:
1.
2.
3.
4.
5.
6.
7.

SCHOLARSHIPS for medical students.
CONTINUING EDUCATION. The Spring Clinical Days.
REUNIONS of your graduating class.
RECEPTIONS at selected medical conventions.
CLUBS on a national basis.
TOURS. Vacations highlighted by scientific sessions.
MISCELLANEOUS. Office Expenses and other services focused at making
ours a complete alumni program.

We invite you to join the physicians who gave last year. Please use the envelope below
and make your check payable to the "Medical Alumni Association."
Your gift will add new meaning and flexibility to our program.

First Class
Permit No. 5670
Buffalo, N. Y.

BUSINESS

REPLY

NO POSTAGE STAMP NECESSARY

IF MAILED IN

POSTAGE WILL BE PAID BY —

Medical Alumni Association
2211 Main Street
Buffalo, New York 14214

Att.: David K. Michael

MAIL

THE UNITED STATES

THE BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET, BUFFALO, NEW YORK 14214

THE HAPPY MEDIUM
Fill out this card; spread some happiness;
spread some news; no postage needed.
(Please print or type all entries.)

Name

__

Office Address
Home Address

Year MD Received

—
—.

If not UB, MD received from
In Private Practice: Yes •

_
No •

In Academic Medicine: Yes •

Specialty,

No •

——

Part Time • Full Time •
School

.

Title
Other:

—

Medical Society Memberships:
NEWS: Have you changed positions, published, been involved in civic activities, had honors bestowed, etc.? —

Please send copies of any publications, research or other original work.