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Part of Buffalo physician, Fall 1973

Text
spring
clinical i
^ days

From the desk of —

Lawrence H. Golden, M.D. '46
President, Medical Alumni Association

Are Alumni Really Necessary?
THE MAJOR STUDENT role is primarily to learn. The faculty have clear
cut assignments in areas of instruction, investigation and administra­
tion. Do alumni have a genuine function? Hopefully, we are more
than the source of potential financial support in a time of tight govern­
mental funds. Other organizations have tried this approach and after
initial enthusiasm, faltered. Many are committed to active teaching
of students particularly in the clinical years that require hospital
assignments. Recently there has been an even greater involvement
of alumni in policy making in various departments as well as in
the administrative aspects of the School of Medicine. As important
as all these functions are — are they enough? I suggest that they
are not. What is needed is a concept that implies tenure, a feeling
of belonging. Although the student graduates, he remains an integral
part of the University the rest of his professional life. His activities
reflect on the University just as the status of the University reflects
on his own personal evaluation. The alumnus must therefore respect
this University and be concerned about its welfare. The University
like every institution in this country has strengths and weaknesses;
problems that are obvious and many that are unrecognized.
The University needs its alumni now more than ever and I suggest
that we become more aware of the University for the single reason
that we are a part of the University, as vital a part of it as its students
and its faculty. Our special strength lies in the fact that we have
moved from its walls and this permits mature surveillance and the
opportunity for wise counsel and guidance. With this concept of
alumni — the problems may not be all solved immediately, but
a spirit that lends itself to grappling with them will be nurtured.•
THE BUFFALO PHYSICIAN

Fall 1973
Volume 7, Number 3

THE BUFFALO PHYSICIAN
Published by the School of Medicine, State University of New York at Buffalo

EDITORIAL BOARD

IN THIS ISSUE

Editor

ROBERT S. MCGRANAHAN

Managing Editor

MARION MARIONOWSKY
Photography

HUGO H. UNGER
EDWARD NOWAK
Medical Illustrator

MELFORD J. DIEDRICK
Visual Designers

RICHARD MACKANJA
DONALD E. WATKINS
Secretary

FLORENCE MEYER

CONSULTANTS
President, Medical Alumni Association

DR. LAWRENCE H. GOLDEN
President, Alumni Participating Fund for
Medical Education

DR. MARVIN BLOOM
Vice President, Faculty of Health Sciences

DR. F. CARTER PANNILL

Executive Officer, School of Medicine

DR. CLYDE L. RANDALL

Vice President, University Foundation

JOHN C. CARTER
Director of Public Information

JAMES DESANTIS
Director of Medical Alumni Affairs

DAVID K. MICHAEL
Director of University Publications

PAUL L. KANE
Vice President for University Relations

DR. A. WESTLEY ROWLAND

2

3
6
14
16
20
23
24
25
27
28
30
35
36
37
38
41
42
45
46
48
51
52
54
62
63
64
65
66
68
69
72
75
76

Are Alumni Necessary? ( i n s i d e f r o n t c o v e r )
Spring Clinical Days
Record Keeping
Drug Reaction
Health Security
Nuclear Medicine
Intern Matching
Outer Space
Resources/Executive Officer
Commencement
Seniors Honored
5,853 Graduates
Oncology Unit
Summer Fellowships
Hospital Head/Dr. Larson
Professors Honored
Dr. Gottlieb/Alumni Receptions
New Experience
Medical Education/Chicago Reception
West Side Health Center
141 Residents, Interns
Learning Center
Environmental Physiology Lab
Alumni Luncheon/Emergency Communications
New Campus
Our First Professor of Medicine by O. P. Jones, M.D.
Physicians Retire
$10,000 Gift
Dog Racing
Dr. Greco
Millard Fillmore Hospital
Research Award
The Classes
People
In Memoriam
Alumni Tours

The cover design by Donaid Watkins features Spring Clinical Days. The picture story
of this annual event is on pages 2-15.

THE BUFFALO PHYSICIAN, Fall 1973 — Volume 7, Number 3, published quarterly

Spring, Summer, Fall, Winter — by the School of Medicine, State University of
New York at Buffalo, 3435 Main Street, Buffalo, New York 14214. Second class
postage paid at Buffalo, New York. Please notify us of change of address. Copy­
right 1973 by The Buffalo Physician.
FALL, 1973

The Stockton Kimball luncheon.

Problem Oriented
Record Keeping

A

SYSTEMS TYPE APPROACH to caring for the patient was described
by Dr. Robert L. Dickman, M'68, at the opening session of 36th annual
Spring Clinical Days. The director of ambulatory services at the Buf­
falo General Hospital said "the use of computerized, problemoriented medical record is now widely accepted." It was designed
by Dr. Lawrence Weed in Cleveland several years ago.
"This is no gimmick. I have seen it work and I am a believer,"
Dr. Dickman said.
Its four components — parelleling the four phases of medicine
— were described by Dr. Dickman. The first is gathering of a data
base (physical, history, profile, lab data). This leads to its second
component, defining the patient's problem(s), — social, psychiatric
and demographic. This problem list then allows the physician to
make plans, the third part of the record, to diagnose and set priorities
in treating the patient. And to plan for patient education. In the
fourth component, the physician notes the progress on patient prob­
lems. This is done subjectively, objectively, through an assessment
where you have what "you think is going on." And finally, plans
for the patient are noted.
Use of this tool all but eliminates one of the greatest problems
in treating a patient, the error of omission where material buried
in the back of the medical record is irretrievably lost. But its advan­
tages are numerous, Dr. Dickman pointed out. Once the problem
list is defined, care becomes more directed. "To have a summary
or index before you helps you make the decisions as 'total problems'
you will deal with on that particular day, and to set priorities,"
he continued. "There are no set rules on the work sheet. Take a
piece of paper and make your own problem list — anyway you
2

THE BUFFALO PHYSICIAN

want to. The data base will differ for different situations but once
it is decided upon, it must be obtained consistently and reliably
on everyone in that group. Never neglect to note a problem simply
because you have no good explanation for it. Always update and
alter the problem list as new data is obtained."
It is a reflection of where you are, where you came from and
perhaps where you are going."
It also has potential as a medical education tool in teaching
students, and house officers. It is a handle by which to audit perfor­
mance, to determine whether care planned has done any good by
consults and review. No longer need there be a standardized hospital
workup for each patient readmitted. One need only refer back to
the problem list "in front of you and staring you in the face." Dr.
Dickman also pointed to the written record that holds up in a court
of law, the saving of time for the physician when a patient fills
out an automated questionnaire and returns it. Now the physician
can practice what he has been trained to do — to diagnose and
to treat.
"The Problem Oriented Medical Record is an invaluable tool
which allows us to deliver more comprehensive patient care. By
using the problem list both for inpatient and outpatient care we
insure continuity and avoid obtaining data in one setting and neglect­
ing it in another.
"By using this record comprehensive care is insured by forcing
the physician to at least consider all of the patient's problems every
time he sees him," Dr. Dickman concluded.

Qnrinn
TA a
^JJilllg LjlllllCal UciyS

"Allergic reactions to drugs continue to be a major medical problem.
And the effects of a combination of drugs on a patient is complicated
and unpredictable. Many times there are serious complications."
That was the unanimous agreement of the four-man panel on Drug
Reactions, Interactions and Toxicity.
Drug dosages needed for optimal therapeutic effects differ widely
among patients. The 'usual dose' of most potent drugs accomplishes
little in some persons, causes serious toxicity in others, and is fully
satisfactory in few. The inability of standard dosage schedules to
exert a sufficiently intense pharmacologic effect in many patients
is often misinterpreted as therapeutic ineffectiveness of drugs. Con­
versely, drug toxicity is often caused by the failure to reduce the
usual dosage appropriate in other patients, according to Dr. Jan KochWeser, associate professor of pharmacology and chief of the clinical
pharmacology unit, Massachusetts General Hospital.
How can we determine the optimal dose of a drug for each
patient? Dosage adjustments are easy when the intensity of a drug's
pharmacologic effects can be accurately and simply quantitated dur­
ing its clinical use. For example, dosage requirements for guanethidine or warfarin can vary by a factor of 50 from one patient to
another. Nevertheless, the drugs are useful therapeutic agents. With
many drugs, the best dosage for individual patients is difficult
because the pharmacologic response is not quantifiable in the usual
clinical situation. The physician may not even know whether tfmj

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FALL, 1973

3

>

Drs. Moloney, Yaffe, Keisman, Koch-Weser, Hurwitz

Spring Clinical Days
fc)

J

Drs. Edward Eschner, Yerby Jones

prescribed dosage is producing the expected therapeutic benefit, particularly when the drug is given for prophylactic purposes.
"Hypersensitivity reactions to drugs can be defined as those
adverse reactions mediated by immune mechanisms, involving either
humoral antibodies or sensitized lymphocytes," Dr. Robert E. Reisman said. Understanding of these hypersensitivity reactions and
appropriate diagnostic tests require identification of the antigen and
type of antibody involved. Most drugs such as penicillin are of small
molecular weight and by themselves are generally unable to stimulate
antibody formation. They act as haptens, combining with body pro­
teins to become antigenic and this leads to antibody formation.
"The multiplicity of allergic reactions which can occur from
one drug such as penicillin is due to differences in the participating
antigen and antibody. Appropriate therapy for a drug reaction is
at least partially dependent upon the immunopathogenesis. From
a clinical viewpoint factors affecting allergic drug reactions include
presence of atopy, prior drug reactions, age, type of drug adminis­
tered, prior drug exposure, and route of drug administration."
Dr. Sumner J. Yaffe told the physicians that administration of
a drug to a pregnant woman presents a unique problem to the physi­
cian. "Not only must the physician consider maternal pharmacologic
mechanisms, but he must also be aware of the fetus as a potential
recipient of the drug. It is estimated that a pregnant woman takes
an average of four or five medications during her pregnancy. In some
of these therapeutic endeavors directed toward maternal disease,
consequences of such drug usage have often been unexpected, with
tragic results in the developing fetus for who the drug was not
intended.
"The teratogenic effects of drugs are dose and time-related. The
fetus is highly susceptible during the first three months of gestation.
It is possible for teratogenic drugs to exert their effects on a fetus
4

THE BUFFALO PHYSICIAN

within 11 days of conception — before the woman suspects her
pregnancy. The mechanisms of teratogenic agents are little
understood, particularly in the human.
"The inadequate enzyme systems of the fetus prohibit them from
metabolizing drugs in the way mature organisms do. The effects
of this inability are not known. Given the present lack of scientific
knowledge, it is felt that throughout the entire period of pregnancy,
administration of any drug should be held to the minimum The
benefits to the mother must be carefully weighted against the possible
harm to the fetus.
Be aware of the problems connected with drug interactions,
warned Dr. Aryeh Hurwitz, a University of Kansas assistant professor
of medicine and pharmacology. "Be able to pinpoint what is happen­
ing if you see an unexpected presence. The combination of drugs
is complicated. We may be unable to predict when an undesired
reaction may occur."
The effect of a drug, he continued, is related to its time duration.
If it is somehow bound in the gut, it prevents absorption. But if
a drug is 99 percent protein bound, its free fraction unbound, it
becomes an active drug — increasing five fold in its activity. Acetic
drug use, he pointed out, replaces other potent drugs from protein
bindings. "And there will be predictable hemorrhaging," Dr. Hurwitz
said. And he emphasized that "if you forget everything else that
I say, don't forget about my caution against the use of Doriden. Don't
use itTj >

A general session

FALL, 1973

5

The M e d i c a l Alumni
A s s o c i a t i o n A w a r d of A p p r e ­
c i a t i o n w e n t t o Dr. C l y d e L. R a n ­
dall, acting dean and vice presi­
d e n t for t h e H e a l t h S c i e n c e s
"for his outstanding leadership
and years of dedicated service
to the School of Medicine and
t h e m e d i c a l c o m m u n i t y . " In h i s
v e r y brief r e m a r k s Dr. R a n d a l l
said " h e w a s t h r i l l e d t o b e a part
of d e v e l o p i n g o u t s t a n d i n g m e d ­
ical s t u d e n t s i n t h i s c o m m u n ­
i t y . A l t h o u g h w e are l a c k i n g i n
n e w , m o d e r n facilities w e h a v e
a medical school in the city
w h e r e t h e p r o b l e m s a r e . " Dr.
Moloney made the presenta­
tion. Mr. Woodcock is also
pictured. •

Health Security
and the
Healing Arts
by
Leonard Woodcock, President
International Union,
United Auto Workers

As I travel about the country I am asked from time to time why
I as a union leader take a major interest in reforming our nation's
health care system. My response is that the safeguarding of health
is of the greatest importance to the worker and his family. He recog­
nizes that without good health the hard fought gains in his economic
situation, won at the collective bargaining table, are almost without
meaning. If his health becomes poor and he can't work, he knows
he and his family can barely live.
The disability rate for families below the poverty level is at
least 50 percent higher than for middle and upper income families.
Our members almost all grew up in poor families. They are all too
aware that a child born in poverty has twice the chance of dying
before age 35 as a child born into a middle income family.
And so union members feel an urgent need to have ready access
to decent, comprehensive health services at prices they can afford.
For some thirty years the UAW has negotiated with employers to
provide funds to make possible this access to good health care. But
despite rapidly escalating expenditures our efforts in this area are
becoming less and less productive.
Our members have been ready and willing to give up wages
for health protection. Today it costs them one month's wages to
pay for private health insurance that does not provide full and needed
coverage. According to HEW, in seven years it will cost them two
month's wages to pay for the same partial protection.
In recent years we have come to recognize that the problems
of fragmentation of health services, disorganization in the delivery
system and shortages of professional personnel, with the resultant
skyrocketing costs will not be solved by our diverting more and
more money from wages to buy private health insurance. The prob­
lems in health care are problems of the society. So we in the labor
movement are making a major effort to bring about needed change
through social reform.
This is the primary reason why I am here today. I have the
greatest respect and admiration for the tremendous advances made
in medicine and science in the last forty years, and for you, the
splendidly trained practitioners who have added to this knowledge,
and who apply it. I am well aware that you are much more interested
in your program subjects like "Nuclear Medicine" and "Drug Reac-

Drs. O'Brien, Randall, Mr. Woodcock, Drs. Golden, Moloney, President Ketter

6

THE BUFFALO PHYSICIAN

Spring Clinical Days

The registration desk

tions and Toxicity" than in an address on health care by a union
president. But you, like we in labor, have no choice. You must con­
cern yourselves with the major problems of health care organization,
delivery and costs, if your valued services are to reach fully those
who require them.
So I have come to Buffalo with the sincere hope that as a result
of meetings such as this, clarifications of viewpoints on the major
issue of national health insurance will emerge.
I must also say that I take some pleasure in noting from your
program, that in part because you are willing to listen to me, the
AMA Council on Medical Education and the Academy of General
Practice will approve ten credit hours for you.
The other day two physicians who are also Congressmen offered
a diagnosis of the current state of health care legislation. One a
Democrat, the other a Republican, they agreed that a national health
insurance law is coming soon. They agreed that physicians will lose
control over their own profession if organized medicine continues
to fight against public demands for real improvements in health
insurance and against more consumer influence in shaping the deliv­
ery of health care. And they agreed that physician self-interest
demands that they cast off their negative approach.
I think that many physicians recognize that the AMA's Medicredit proposal is a negative approach. It sets the course of medical
care in a hard and fixed frame when it should invite innovation.
It assures higher costs when it should reduce waste and duplication.
It encourages unnecessary surgery when it should promote preven­
tive medicine and quality controls. It is insurance industry oriented
when it should be patient oriented.
To illustrate one of its many serious deficiencies, look at the
dental benefits. The AMA was criticized by the American Dental
Association for excluding dental benefits from the previous Medicredit bill. This year, the AMA representatives are boasting of the
inclusion of dental benefits. But they fail to make clear that th
FALL, 1973

7



Spring Clinical Days

Mrs. Stockton Kimball

benefits are limited to children age 2 to 6. They don't broadcast
the fact that there is a $100 deductible per child, per year.
This is the tooth fairy in reverse: the parent will leave $100
under the pillow before the dentist provides any services.
The dental benefit, really, is consistent with the rest of the Medicredit bill in that it completely ignores the needs of both patients
and physicians. Reforms are conspicuous by their absence.
The lure of tax credits would theoretically result in better and
broader health insurance coverage for all. But the facts are that only
the working poor with incomes below about $6,000 annually would
have any real incentive to buy the policies proposed by the AMA.
And they would be incouraged to buy the worst kind — individual
policies that return only 50 cents on the dollar to the health system.
The other 50 cents stays with the insurers.
The whole Medicredit plan is really a sellout to the insurance
industry. As practicing physicians, you should tell the AMA you
won't buy it. But to date, I wonder how many physicians have had
the time, or taken the time, even to read the national health insurance
plan that is being presented in your behalf to Congress. You ought
to read it and understand it because 200 Congressmen and Senators
have signed their names to it on the word of AMA lobbyists that
you, the physicians of America, are solidly behind it.
Few people have read and fully digested the 17 different national
health insurance bills before the Congress. It's too much to ask of
doctors. So I'm here today to talk about just two of them — the
Health Security bill and the AMA's Medicredit bill. And I'm here
to tell you that, according to your own principles and standards,
the Health Security bill rather than the AMA bill has the doctors'
interest at heart.
There's a high level game being played by the AMA. They are
using your dues to promote the interests of the insurance industry.
You'd think that Mutual of Omaha and Aetna would spend their
own money to lobby Congress for favors to the private insurance
companies. But the AMA is spending your money for that purpose.
The Medicredit bill does not serve doctors well. It does not serve
the interests of patients. But it certainly will create billions of dollars
in new business and profits for the insurance companies.
It has been said a thousand times by the AMA hierarchy that
we who support the Health Security bill don't care about you. I'm
here to tell you we care a great deal about you. It is time we had
a sensible dialogue to explore and expand the wide areas of agreement
that we share. No such dialogue has been possible with an intransig­
ent organization purporting to represent you that is responsive only
to its most conservative constituents. But I say to you that if you
or any other group of physicians has suggestions about improving
the Health Security bill, within its broad principles, then we are
eager to hear from you and to sit down and talk with you. We have
done this with the 26 physicians who are members of our Committee
for National Health Insurance and with literally hundreds of others.
We can't talk with the medico-politicians in Chicago. They tell you
that Health Security will come between patient and doctor. Show
us where that is, and we'll change it.
To my knowledge, the AMA has never released any poll of its
membership on the subject of national health insurance but the
8

THE BUFFALO PHYSICIAN

An honor guard table

magazine, Modern Medicine, reported the reactions of 17,000 physi­
cians last year. Understandably, because they do not like change,
most physicians were against any form of national health insurance.
But, those who saw any merit in national health insurance proposals,
by a slightly higher percentage, preferred the Health Security program
to those of the AMA or the Nixon Administration. A later poll, con­
ducted by the Gallop Organization, found 51 percent of physicians
favorable to some form of national health insurance. Numerous
national and state polls show that about two-thirds of all patients
want governmental health insurance to replace private insurance,
which most find ineffective or defective, or both.
Doctors and patients may differ on what are the most pressing
problems in American health care. But they agree on many things.
They agree that our present health insurance programs aren't working
well and ought to be changed. They agree that we ought to expand
medical education and produce more doctors and also physicians'
assistants. They agree that hospital facilities ought to be expanded
and improved and that both basic and applied research in health
science and health care should be well-funded.
These are matters on which both patients and doctors are in
firm agreement. But to date in Washington, we find that representa­
tives of patients are struggling to stop the budget-cutters at the OMB
from axing health programs that ought to be strengthened, while
the AMA, in line with its consistent policy that health care for all
Americans should be the responsibility of no one in particular, has
raised no audible objection or concurred with most of what's going
on.
Meanwhile, Federal Administration engages in prolonged flights
of fancy about its accomplishments, but the President's health budget
reveals a harsh insensitivity to the needs of both patients and doctors.
President Nixon wants to cut into health services research and
development and cut out entirely the regional medical program. He
gives no additional support to biomedical research and proposesj ^
FALL, 1973

9

On June 18 President Nixon
signed a major bill that would
extend through the fiscal year
health programs totaling $1.2
billion. Included were several
programs the Administration
had planned to eliminate —
Hill-Burton hospital construc­
tion at $197-million, regional
medical programs at $159million, public health and other
training program at $68-million
and new mental health pro­
grams at $174-million. •

A class reunion dinner

to phase out all NIH fellowship and training grants. Who will provide
for biomedical research which is essential to your clinical practice
when the government support stops? The Administration says it
will come from the normal economic forces of the private market­
place. The faculty and governing body of your Medical School here
will tell you such a statement at best derives from ignorance and
at worst deceit.
Because Community Mental Health Centers have demonstrated
great success, Mr. Nixon and Mr. Weinberger want to stop supporting
them. But what does this mean to your patient: the adolescent who
needs the counselling you are unable to provide in a busy practice,
the addict, the alcoholic, the emotionally disturbed? Within this
troubled society many look to the Community Mental Health Center
as a vital, and often only resource. But of the 2,000 centers planned
throughout the nation, only 560 have been established. They have
relieved the overcrowding and stress in state mental hospitals and
the pressures on the family physician. Mr. Nixon wants the Commun­
ity Mental Health Center legislation to expire this June 30th.
Even though the OMB has developed ingenuous devices for
obscuring their intentions, the facts are that no health program
entirely escapes the budget cutter's axe. Not health manpower educa­
tion, nor preventive health services, nor disease control. Not allied
health training nor population research and family planning, nor
medical libraries. Instead of proposing innovation for the Hill-Burton
program, they propose interment. They would replace Public Health
Service hospitals and clinics with vacant lots. They would cut back
on Medicare.
It is not surprising that the AMA benignly watches as these
cuts occur. Nobody has ever accused the AMA of any leadership
in protecting the patient's rights or improving his lot. But everyone
knows that the practicing physician is deeply concerned about his
patient. And if he does not have the time to crusade for the rights
and needs of other doctors' patients, he is still concerned.
10

THE BUFFALO PHYSICIAN

I say now is the time to express your concern. But let your
Congressman know that you support good governmental health
activities and oppose budget cuts that rank health low in national
priorities. And let Mr. Nixon know, too.
Last year I had the privilege of addressing the annual meeting
of the American Society of Internal Medicine at Atlantic City. I made
the point then that of all the proposals before the Congress for national
health insurance, only the Health Security bill measured up to that
Society's own standards.
It was and is the only bill meeting their first principle — "that
every American should have comprehensive health insurance cover­
age." The AMA plan, the Administration plan and each of the others
fails to provide comprehensive coverage. Even though so-called
"catastrophic insurance" is being promoted in these plans this year,
their enactment would only result in a delay of comprehensive cover­
age. The prospect of catastrophic insurance already is encouraging
promoters and entrepreneurs both within and outside the medical
profession to "go public" with exotic and esoteric machinery and
treatment, some of it bordering on quackery and little of it geared
to the needs of the physician and his patient.
Catastrophic insurance says to the consumer: "If you get real
sick, we'll start paying your bills. But don't get too sick because
we'll stop paying them."
That isn't what you need to practice good medical care. It isn't
what your patient needs. The primary physician is the forgotten
man in that equation, and so is his patient. The philosophy that
holds that a patient's serious illness should be a financial disaster
for his family is inconsistent with the professional motivation of
the physician.
In the Health Security program, which emphasizes early diag­
nosis and treatment, the primary physician has a special place. If
he is a solo practitioner, he is offered alternatives in the payment
methods which are not available to other specialties. He can elect
to be paid by fee-for-service or by a capitation method, with fair
and reasonable sums paid him for each patient. If he selects the
capitation method, he is encouraged through financial incentives
to establish formal linkages for his patients with other health care
providers and institutions, including hospitals, nursing homes and
home health services.
In other words, he will be able to write an order for his patient
outside the hospital just as he now does in the hospital, and thereby
activate a system providing needed services for his patient.
And in selecting capitation, he is assured not only of economic
parity with the fee-for-service practitioner, but funds from a separate
account for personnel to run a good office.
If he is in a prepaid group practice involving other specialties,
the primary physician practicing under the Health Security program
will receive special financial and professional recognition of his
primary role as the provider and manager of comprehensive personal
health care. And he will have his own "Professional Standards
Review Organization" to give practical effect to the art and science
of quality controls.
I think the public is becoming more acutely aware of the need
for better quality controls in the medical care system. Particularly
FALL, 1973

11

Spring Clinical Days

President R o b e r t L. Ketter
told the al umni that pre­
eminence in medical education
is our goal. "We want to develop
a strong l i n k b e t w e e n t h e M e d i ­
cal School and the University.
W e h a v e just h i r e d a n e x t r e m e l y
a b l e v i c e p r e s i d e n t fo r t h e
H e a l t h S c i e n c e s (Dr. P a n n i l l ) ,
a n d w e are s e a r ch in g for a n e w
dean for the School of
Medicine. We want a nationally
prominent man. Your aiumni
president, Dr. Golden, is a
member
o/
the
search
committee." •

the stream of reports of unnecessary surgery and its effects on friends
and neighbors is causing consternation. I know many of our five
million UAW members and their families are shocked by these
reports.
We also agree that a well trained physician is in an excellent
position to evaluate the quality of care. We have some trouble in
understanding why he must be from the local group and subjected
to the social, organizational and referral pressures that come from
having to pass judgment on one's neighbors and friends. We wonder
if a physician is any less competent to review a surgical report or
a tissue analysis if his practice is four hundred miles removed from
the site of the surgery, than if it is four miles removed.
Is it unreasonable to expect that patients may have meaningful
views about how they are handled by physicians, the ways in which
they are referred, the information they are given or not given about
their conditions, and the instructions which are passed on to them
during the following treatment? Our experience in the UAW leads
me to believe that these are important aspects to quality which require
consumer input.
The overwhelming majority of consumers have no knowledge
as to whether they have had too many procedures inflicted upon
them or not enough. They have no assurance that the care they
receive is, in fact, consistent with the best modern medical knowl­
edge. They must look to you and the control procedures you set
up to give them this assurance.
Most encounters with physicians and health services take place
not in hospitals, but behind the closed doors of physicians' offices.
In this setting there are exceedingly few if any checks on what hap­
pens.
We therefore are in agreement about the need for effective quality
safeguards. If you will broaden your view to take into account the
quality considerations as seen by consumers, it seems to me it is
quite possible for us to work out with you an appropriate mechanism.
The AMA has spread a myth about the Health Security program
that it is "monolithic". It has become their favorite scare word. I
want to dispel that myth right now, if I can.
We believe there ought to be a Social Security-type trust fund
to pay for health services, instead of an army of insurance company
claims clerks. There are presently 1800 insurance companies selling
thousands of different kinds of health insurance policies. But we
do not believe in a monolithic structure for the delivery of services.
We believe in pluralism. We believe that many types of organizational
arrangements should be encouraged and evaluated. Contrary to what
doctors are being told, we do not reject solo practice, fee-for-service
medicine. We favor flexibility, not rigidity. And we don't favor
socialized medicine. It is not our position that doctors should become
civil servants or that hospitals should be taken over by the govern­
ment. The people who are making these allegations about a "mono­
lithic" Health Security bill know full well that the bill encourages
pluralism in the delivery system. Any who takes the time to read
it knows it, too.
Your society and our union agree there is a great need to increase
the availability of medical services, and that increasing physician
productivity should receive equal emphasis with increasing the
number of physicians.
12

THE BUFFALO PHYSICIAN

Dr. Edward Zimmerman entertains the 1923 class.

Obviously, we cannot project needs for future physician man­
power without assessing possible productivity gains through new
organizational arrangements. This should be based on reasonable,
practical planning. But once there is identification of goals, we should
move realistically toward their attainment.
.
1 TA
In 1931, there were 1,097 persons in the United States for every
OPTLILG LJIIIIICCII IJciyS
general practitioner. In 1970, as you well know, there were almost
four times that many persons per general practitioner and an increas­
ing number of them were foreign nationals and graduates of foreign
medical schools. Furthermore, the shortages of health personnel in
the urban ghettos and the rural areas have reached the desperate
stage. Not only are they statistically far worse off than other areas,
but as you well know, the majority of these physicians are elderly,
often past the retirement age. It is therefore of little value to make
funds available to consumers when with those funds they cannot
obtain the needed services.
The Health Security Act implements the principle of increasing
the availability of medical services and increasing physician produc­
tivity. There is a substantial Resources Development Fund to provide
new support for the education and training of new health profession^

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PHOTO* I £[£080*1

The winning exhibit.

Dr. Oscar Oberkircher

Nuclear Medicine

Dr. Steinbach

als, with priorities for groups which have been disadvantaged in
the past. There is technical assistance and the start-up support for
new health plans. There is a way to pay for all the services provided
by these plans. There are incentives for primary physicians to utilize
ancillary services for their patients, including physician assistants
as appropriate.
Health Security is a program providing universal coverage for
patients and incentives for doctors to better organize themselves
to deliver care, and with cost containment and quality safeguards.
The doctor will remain the key and essential figure. Only he
will prescribe for his patient and the financial barrier between them
will be removed.
I am here today to suggest that a new spirit of cooperation
between the physician and the representatives of his patients is possi­
ble and desirable. Cooperatively, we can deal with all of the problems
which currently plague the delivery of health care in this country.
We can work together toward the goal of a health care system approp­
riate to the needs and desires of our advanced nation. Such a system
* S P o s s i ^^ e o n ^ i n a s o c i ety which has its priorities straight — a
society that puts the health and well-being of its people at the top
of its agenda.

"Ninety-five per cent of nuclear medical procedures are diagnostic
in character. These studies have reached their present level of impor­
tance in the practice of medicine because they provide vital diagnos­
tic information with little or no discomfort to the patient." Dr. Merrill
A. Bender, clinical professor of nuclear medicine also said "the radia­
tion dose to the patient is very modest and in most instances compar­
able to that received from diagnostic X-ray studies.
"In the early days of nuclear medicine it was hoped that radio­
isotopes would provide an effective tool for the treatment of a signifi­
cant number of malignant and benign diseases. Unfortunately this
hope has not been realized, and only two or three disease states
have been successfully treated with these materials. These include
hyperthyroidism and selected cases of cancer of the thyroid and
advanced heart disease treated with radioactive iodine, and certain
blood disorders."
Dr. Bender told the physicians that "imaging" of radioisotope
distributions has allowed us to detect pathological processes in many
different organs — the brain, thyroid, liver, pancreas, kidneys, bone
as well as circulating ailments involving lungs, heart, great vessels
and spleen.
Of equal importance in the field of nuclear medicine is the
evaluation of function and the measurement of the size of various
'spaces' in the body — blood volume. In just 10 minutes the circula­
tory condition of a patient undergoing major surgery can be evaluated.
The most common function study is that of the thyroid gland where
a radiation detecting technique determines the percent trapped there.
By measuring concentration/excretion through the kidney, one can
diagnose and evaluate nephritis, hypertension, renal transplant and
for those concentrations that localize in the liver, evaluation of
cirrhosis and hepatitis.
14

THE BUFFALO PHYSICIAN

"The quantitative scintillation camera gives us a new diagnostic
procedure. Not only does it visualize redioisotope distribution but
quantifies the amount of compound in a specific location as a function
of time. We can also evaluate the degree of cardiac disability in
acquired heart disease and measure renal and cerebral blood flow.
The latter is proving very useful in the evaluation of strokes."
The thyroid scan or "scintigram" is a pictorial representation
of the regional activity of the thyroid gland. "The scan is most fre­
quently helpful in situations where the thyroid gland is palpably
enlarged. In patients with normal or slightly reduced thyroid func­
tion, the thyroid scan may be useful in evaluation of palpable nodules.
These nodules are classified as 'hot, warm or cold', by whether they
concentrate more, the same or less radioactivity than does the sur­
rounding tissue. When the nodule is 'warm or cold', the value of
the scan depends largely upon the morphology which it
demonstrates."
Another panelist Dr. Jehuda J. Steinbach pointed out that the
field of competitive radioassays is the most rapidly expanding field
in nuclear medicine today. "A few years ago only a few selected
laboratories could perform only one or two selected tests. By contrast
today the available procedures and laboratories that can perform
them are almost too numerous to count."
Brain scanning has become widely available during the past
10 years, according to Dr. George J. Alker. "Today most hospitals
are equipped to perform this examination and in most nuclear
medicine departments it is the single most frequently performed
imaging procedure. Although originally intended to be a means of
localizing brain tumors, it was soon recognized that a number of
non-tumorous diseases of the central nervous system can also be
diagnosed and localized by this technique. Today brain scanning
is firmly established as an important vart of the workup of patients
with a wide variety of neurological diseases."
Dr. R. Ronald Toffolo reviewed the 205 placental scans carried
out in the nuclear medicine department at Millard Fillmore Hospital
from April 1965 to March 1973. "Approximately three per cent of
patients show vaginal bleeding in the last trimester of pregnancy; of
these placenta previa is the cause in less than one per cent. A standard
five inch crystal rectilinear scanner and flat field collimator are used."

Dr. Hays

Spring Clinical Days

Dr. Yehuda G. Laor pointed out that liver scanning is rather
simple and does not involve any patient preparation. "Spleen scan­
ning has become easier and simpler in recent years with the intro­
duction of Technetium 99m Sulfur Colloid, and Indium-113m colloid
for liver scanning. Because of the short half-life of these isotopes,
larger doses can be injected for routine studies. Pancreas scanning
has not progressed in recent years. And because of the difficulty
of performing and interpretation of pancreas scans as well as the
high cost, these studies are not as widely performed as liver and
spleen scans."
Dr. Joseph Prezio discussed pulmonary emboli and the lung
scan; Dr. Monte Blau, nuclear medicine overview; Dr. Suraj P.
Bakshimd, bone scanning; Dr. Marguerite Hays, thyroid scan, and
Dr. Eugene V. Leslie, clinical professor of radiology, chairman of
the radiology department and acting chairman of the nuclear
medicine department, moderated the panel. •
FALL, 1973

15

.

r.rvrm:,

Relaxing in the student lounge.

Intern
Matching

After announcing the "matchings" Dr.
Cummiskey said he was leaving the
University to join the department of
radiology at the Meyer Hospital as a
resident.

Michael Haberman, Louis Zibelli, Mark Heller

"Two thirds of you were 'matched' with your first choice of hospital
and 85 percent ranked with a hospital listed among your first three
choices." That's what Dr. Thomas G. Cummiskey, assistant dean
at the School of Medicine told the 115 members of the graduating
class. To further point out the high calibre of this class he pointed
to the "matches" with the prestigious Johns Hopkins Hospital, Los
Angeles Harbor Hospital, Vanderbilt, Michael Reese and Columbia
Presbyterian Hospitals.
Under the National Internship Matching Plan, which attempts
to match the preferences of the students with those of the hospitals
throughout the country, 44 will remain in Buffalo and 22 others
will continue their training in other parts of New York State. The
remainder will go to 20 other states, with California receiving the
largest number of 10. One will go into the Public Health Service
in New York City.
Fourteen members of the class did not participate in the matching
plan electing to make their own arrangements.
Eighty-two of the seniors chose to continue their training at
University-affiliated hospitals. Twenty-nine others will go directly
into specialty residencies, bypassing the internship which appears
to be phasing out throughout the country. Of this group, six have
selected the specialty of family practice, previously known as general
practice. Four will complete their training at the Deaconess Hospital's
Family Practice Program.
The University Program at Buffalo General and Meyer Memorial
Hospitals received all 20 of the interns it requested in straight
medicine and 14 of the 15 asked for as general rotating interns.
Children's Hospital received eight of the 14 pediatric residents it
requested. Two of the three psychiatry residencies were filled at
the Meyer and one of five surgery interns requested there was filled.
Four of 12 surgery residents were filled at the combined Buffalo
General/Meyer Hospitals program as well as. two of four rotating
general.
16

THE BUFFALO PHYSICIAN

BRUCE M. ABRAMOWITZ, St. E l i z a b e t h , Boston, straight medicine
WILLIAM J. ACKERMAN, University of C a l i f o r n i a ( S a n D i e g o ) , A f f i l i a t e d H o s p i t a l s , r o t a t i n g
CHARLES L. ANDERSON, Deaconess Hospital, Buffalo, family practice residency
FREDERICK K. BECK, Bridgeport Hospital, Connecticut, rotating
WILLIAM S. BIKOFF, Buffalo General/Meyer Hospitals, Buffalo, rotating medicine
DONALD R. BLOWERS, Hennepin County General, Minnesota, rotating
LAWRENCE B. BONE, E.J. Meyer Memorial Hospital, Buffalo, straight surgery
DAVID H. BREEN, Cedars Sinai Medical Center, Los Angeles, straight medicine
FREDERIC R. BUCHWALD, Public Health Service, New York City, rotating
FERNANDO J. CAMACHO, Mont e f i o r e H o s p i t a l , N e w Y o r k C i t y , s t r a i g h t medicine
JACK R. CAVALCANT, Meadowbrook Hospital, East Meadow, N.Y., rotating medicine
YUNG CHEUNG CHAN, Henry Ford Hospital, Detroit, surgery residency
ABBY COHEN, Herrick Memorial Hospital, Berkeley, rotating
JEREMY COLE, University of California (Los AngelesJ, straight medicine
RAYMOND DATTWYLER, University Hospital, Madison, Wisconsin, straight medicine
MARK M. DECHTER, University 0/ Virginia Hospital, Charlottesville, family practice
RICHARD DUNDY, Detroit General Hospital, Michigan, rotating
THOMAS DWYER, Buffalo General/Meyer Hospitals, Buffalo, rotating
DEMETRIUS ELLIS, Children's H o s p i t a l , Pittsburgh, Pa., straight pediatrics
LEE A. EVSLIN, Maine Medical Center, Portland, rotating
RETA D. FLOYD, Huntington Memorial H o s p i t a l , Pasadena, C a l i f o r n i a , r o t a t i n g
ROBERT G. FUGITT, Deaconess Hospital, Buffalo, straight surgery
VINCENT FUSELLI, University Hospital, Columbus, Ohio, straight pediatrics
KENNETH L. GAYLES, M i c h a e l Reese Hospital, C h i c a g o , straight m e d i c i n e
THOMAS E. GILLETTE, Washington Hospital, D.C., rotating
JOSEPH M. GRECO, Millard Fillmore Hospital, Buffalo, surgery residency
RICHARD GREEN, St. Joseph's Hospital, Phoenix, Arizona, straight medicine
MICHAEL A. HABERMAN, E.J. M e y e r Memorial H o s p i t a l , B u f f a l o , p s y c h i a t r y residency
THOMAS E. HAGUE, D e a c o n e s s H o s p i t a l , B u f f a l o , general rotating
RALPH R. HALLAC, B u f f a l o G e n e r a l / M e y e r H o s p i t a l , B u f f a l o , straight m e d i c i n e
MAXINE D. HAYES, V a n d e r b i l t University, A f f i l i a t e d H o s p i t a l s , Tennessee, straight pediatrics
MARC E. HELLER, Mary Imogene Bassett H o s p i t a l , C o o p e r s t o w n , N . Y . , rotating
JEFFREY P. HERMAN, Monte/iore Hospital, New York C i t y , s t r a i g h t pediatrics
FREDERIC M. HIRSH, Deaconess Hospital, B u f f a l o , f a m i l y p r a c t i c e r e s i d e n c y
DONNA HRUSHESKY, B a l t i m o r e C i t y H o s p i t a l s , Maryland, straight medicine
WILLIAM HRUSHESKY, B a l t i m o r e C i t y H o s p i t a l s , Maryland, straight medicine
ROBERT HUDDLE, R o c h e s t e r General H o s p i t a l , N e w Y o r k , straight surgery
ISRAEL J. JACOBOWITZ, Bellevue H o s p i t a l C e n t e r , N e w Y o r k C i t y , surgery residency
BRUCE R. JAVORS, N.Y. Med. College/Metropolitian, New York City, radiology/diagram
residency
DANA E. JOCK, Mary Imogene Bassett H o s p i t a l , Cooperstown, N.Y., rotating
LEELAND JONES, Buffalo General/Meyer Hospitals, Buffalo, rotating medicine
BARRY A. KASSEL, H a r t f o r d H o s p i t a l , Connecticut, surgery residency
DOUGLAS L. KIBLER, Buffalo General/Meyer Hospitals, Buffalo, rotating
JOSEPH T. KING, Cleveland Clinics, Ohio, general rotating
MICHAEL KLEIN, Syracuse Medical Center, New York, ob/gyn residency
JOHN T. KLIMAS, Johns Hopkins Hospital, Baltimore, pediatrics residency
PAUL KURITZKY, Millard Fillmore Hospital, Buffalo, rotating medicine
SHARON KURITZKY, Millard Fillmore Hospital, Buffalo, rotating medicin

FALL, 1973

17

ROBERT S. LaMANTIA, B u f f a l o G e n e r a l / M e y e r H o s p i t a l s , B u f f a l o , r o t a t i n g medicine
DANA P. LAUNER, North S h o r e / M e m o r i a l H o s p i t a l , N e w Y o r k C i t y , surgery residency
DEXTER S. LEVY JR., Santa Barbara C o t t a g e H o s p i t a l , C a l i f o r n i a , rotating
NANCY L. LIEBERMAN, New E n g l a n d Medical Center ( T u f t s ) , straight p e d i a t r i c s
JEFFREY LIGHT, C e d a r s Sinai M e d i c a l C e n t e r , Los Angeles, straight medicine
JOHN I. LOWENSTEIN, Washington H o s p i t a l , D . C . , rotating general
THOMAS A. LOMBARDO JR., Millard F i l l m o r e H o s p i t a l , B u f f a l o , surgery residency

The Art Mruczeks

JAMES S. MARKS, University o f C a l i f o r n i a ( S a n F r a n c i s c o ) , pediatrics residency
MARY JANE MASSIE, E.J. Meyer Memorial Hospital, Buffalo, psychiatry residency
C H A R L E S J. M c A L L I S T E R , M e a d o w b r o o k H o s p i t a l , E a s t M e a d o w , N . Y . , s t r a i g h t m e d i c i n e
RICHARD B. McCORMICK, Charity Hospital, Louisiana, straight surgery
DANIEL J. McMAHON, Deaconess Hospital, Buffalo, family practice residency
STEVEN J. MORRIS, Grady Memorial Hospital, Atlanta, straight medicine
ARTHUR W. MRUCZEK, Buffalo General/Meyer Hospitals, Buffalo, straight medicine
MICHAEL V. MURPHY, Millard Fillmore Hospital, Buffalo, rotating general
JOSEPH M. MYLOTT, Deaconess Hospital, Buffalo, straight surgery
STEPHEN A. NASH, Maricopa County G e n e r a l , P h o e n i x , rotating general
VINCENT NAT A LI
TIMOTHY NOSTRANT, U n i v e r s i t y o f Michigan, A f f i l i a t e d Hospitals, Ann A r b o r ,
straight medicine
PATRICK L. O'CONNOR, M i l l a r d Fillmore Hospital, r o t a t i n g surgery
PAUL A. ORENS, St. Peters Hospital, Albany, radiology/general residency
RONALD D. OSGOOD, Mercy Hospital, Buffalo, rotating general
EUGENE OSTROFF, Buffalo General/Meyer Hospitals, Buffalo, rotating general
PAUL A. PALMA, Presbyterian H o s p i t a l , N e w Y o r k C i t y , straight pediatrics
GARSUTIS K. PALYS, Hershey M e d i c a l C e n t e r , P e n n s y l v a n i a , f a m i l y p r a c t i c e r e s i d e n c y
ROBERT L. PENN, N.C. Memorial, Chapel H i l l , N . C . , straight medicine
DANIEL A., PIETRO JR., B u f f a l o G e n e r a l / M e y e r Hospitals, B u f f a l o , r o t a t i n g medicine
IRA H. PORES, B u f f a l o General/Meyer H o s p i t a l s , B u f f a l o , rotating medicine
MELVIN R. PRATTER, A l b a n y H o s p i t a l , N e w Y o r k , straight medicine
JOHN E. PRZYLUCKI, M i l l a r d Fillmore H o s p i t a l , B u f f a l o , surgery residency
STEVEN T. PUGH, M e d i c a l C o l l e g e o f Virginia, Richmond

The Dan Wistrans

The Ralph Hallacs

THE BUFFALO PHYSICIAN

T h e babies stole t h e s h o w

Re t a Floyd (right) and friend

ANDRE RASZYNSKI, C h i l d r e n ' s H o s p i t a l , B u f f a l o , pediatrics residency
SCOTT G. READER, Buffalo General/Meyer Hospitals, Buffalo, rotating general
MICHAEL A. RIOZZI JR., St. Mary's Hospital, Long Beach, California, rotating
LYNNE S. ROSANSKY, Maimonides Hospital, Brooklyn, rotating medicine
J U D I T H R O U S S O , E.J. M e y e r M e m o r i a l H o s p i t a l , p s y c h i a t r y r e s i d e n c y
JACOB D. ROZBRUCH, New York/Memorial Hospital, pediatrics residency
JON P. RUBACH, Buffalo General/Meyer Hospitals, Buffalo, rotating medicine
BARRY SANDERS, B u f f a l o General/Meyer H o s p i t a l s , B u f f a l o , rotating medicine
MICHAEL A. SANSONE, B u f f a l o G e n e r a l / M e y e r H o s p i t a l s , B u f f a l o , straight medicine
MICHAEL R. SAVONA, Presbyterian H o s p i t a l , N e w Y o r k C i t y , straight medicine
MARK N. SCHEINBERG, C h a r i t y H o s p i t a l , Louisiana, straight ob/gyn
ARNOLD W. SCHERZ, Bronx M u n i c i p a l H o s p i t a l C e n t e r , B r o n x , pediatrics residency
ROBERT SCHULMAN, Children's Hospital, B u f f a l o , pediatrics residency
DENNIS SCHUSTER, University o f K e n t u c k y M e d i c a l C e n t e r , L e x i n g t o n , straight surgery
ARTHUR SGALIA, B u f f a l o G e n e r a l / M e y e r H o s p i t a l s , B u f f a l o , straight medicine
ROGER SIMON, B u f f a l o G e n e r a l / M e y e r Hospitals, B u f f a l o , rotating medicine
ROY W. SLAUNWHITE III, Children's H o s p i t a l , B u f f a l o , pediatrics r e s i d e n c y
STEPHEN A. SMILES, Bellevue H o s p i t a l C e n t e r , N e w Y o r k C i t y , straight medicine
RICHARD A. SPECTOR, Charity H o s p i t a l , Louisiana, rotating
DENNIS E. STEMPIEN, University of Minnesota, Minneapolis, straight medicine
DARLENE THORINGTON, Deaconess Hospital, B u f f a l o , f a m i l y practice residency
T h e Barry Sanders

JOHN P. VISCO, E.J. M e y e r Memorial H o s p i t a l , B u f f a l o , straight medicine
RONALD L. WASHBURN, University of Michigan, Ann Arbor, r a d i o l o g y / d i a g . r e s i d e n c y
THOMAS D. WASSER, Rochester G e n e r a l H o s p i t a l , N e w Y o r k , rotating general
MATTHEW H. WEBER, E.J. M e y e r Memorial H o s p i t a l , B u f f a l o , rotating surgery
RICHARD L. WIGLE, K e e s l e r A i r Force Base, B i l o x i , M i s s . , straight medicine
GARY J. WILCOX, Los Angeles County Harber General, C a l i f o r n i a , s t r a i g h t p a t h o l o g y
CHARLES E. WILES III, E.J. M e y e r Memorial Hospital, B u f f a l o , surgical r e s i d e n c y
EDWARD L. WILSON, Millard F i l l m o r e H o s p i t a l , B u f f a l o , rotating medicine
JONATHAN WISE, Memorial Hospital, New York City, pediatrics residency
DANIEL C. WISTRAN, Rhode Island H o s p i t a l , Providence, straight medicine
ROBERT A. WOOLHANDLER, B u f f a l o General/Meyer H o s p i t a l s , B u f f a l o , rotating medicine
HENRY M. WYMBS, B u f f a l o General/Meyer Hospitals, B u f f a l o , rotating medicine
LYNDA M. YOUNG, Children's Memorial Hospital, C h i c a g o , straight p e d i a t r i c s
LAWRENCE ZEMEL, Children's H o s p i t a l , B u f f a l o , pediatrics residency
LOUIS R. ZIBELLI, Monte/iore H o s p i t a l , N e w Y o r k C i t y , straight medicine
FALL, 1973

19

In cold room working with electrophoresis are Mrs. Eddy and Drs. Giilman, Bigazzi and Van Oss.

I

Separating
Living Cells
in
Outer Space

20

NCREASING THE DEFENSE MECHANISMS of those
who suffer from immunological disease may be
a step closer to reality through pioneering
investigations underway by a team of immunologists at the Medical School. Headed by Dr. Pierluigi E. Bigazzi, the team is devising a way to
separate living cells through their electrical
charge, something that has always been hard
to do because of interference from the force of
gravity.
Their proposal, to study this phenomenon
where there is no problem — in outer space
where at zero gravity there is no cell sedi­
mentation and therefore separations can be per­
formed easily with simple devices — was
awarded a major NASA contract.
The group who is working with the research
associate professor of microbiology are Dr.
Cetewayo Giilman, research associate; Mrs.
Martha Eddy, research technician, the staff of
the department of microbiology's immunochemistry laboratory directed by Dr. Carel J. van
Oss. Consultants are Drs. Noel R. Rose and Stan­
ley Cohen of The Center for Immunology at the
University.
THE BUFFALO PHYSICIAN

"The most important cell for immunologic
reactivity," said Dr. Bigazzi who is a graduate
of the University of Florence (Italy), "is the
lymphocyte." Subdivided into at least two
populations, they are T (thymus-dependent)
and B (bone marrow-derived) cells. T cells,
involved in cell-mediated immunity, make up
a variety of substances known as "lymphokines." B cells, on the other hand, are involved
in antibody formation.
Deficiencies in T and/or B cells cause severe
human diseases such as agammaglobulinemias,
Di George's syndrome, etc. Or they may occur
in patients with various malignancies such as
Hodgkin's disease and chronic lymphatic
leukemia. "It is clear," Dr. Bigazzi said, "that
if we want to restore immunological compe­
tence to a deficient individual we must be sure
that we are giving the right kind of lymphocytes
or their products to the patient. If we can do
so, we can specifically strengthen the protective
defenses of those who suffer from certain types
of tumors, chronic infections or who need to
undergo organ transplantations."

Electrophoretic separations are done by
allowing the negatively charged cells — in sus­
pension in water — to migrate in an electric
field toward the positive electrode. T cells, more
negatively charged than B ones, must migrate
faster. But during the time it takes for T cells
to run significantly ahead of B cells, all of the
cells will have settled to the bottom of the vessel
at one (1.0) gravity on earth.
Until now the only way that T and B cells
have been separated is through microanalytic
methods that have produced minute quantities
and with the help of very complicated steady
state fluid flow electrophoresis contrivances.
The Buffalo team hopes to find a simple method
to separate them in larger amounts for later use
in clinical situations.
But to do this they must find ways to
simulate by different densities something close
to the zero gravity that is found in outer space.
Explained Dr. van Oss, "we must be able to
simulate on earth what we hope to accomplish
in outer space." And the team has already begun
to get resultsj ^

Dr. Gillman and Mrs. Heide
count
the
number
of
lymphocytes in fraction
separated preparation by
electrophoresis.

FALL, 1973

21

"With the aid of heavy water at one grav­
ity," the professor of microbiology continued,
"we have been able to fool lymphocytes into
thinking for a short time that they are at zero
gravity. And by using electrophoretic migration
from the bottom to the top of a tube, we have
recently succeeded in having the most nega­
tively charged (T) cells overcome gravity and
rise to the top before the B cells."
While separations are now being achieved
with quantities of cells running about several
hundred thousand per fraction, the team hopes
to separate millions to billions of cells. When
enough data are collected in their laboratory
on earth, experiments for Skylab and its con­
tinuous Shuttle will be planned. But first prior­
ity of the team is to devise a method to freeze

lymphocytes for their trip to Skylab and
immediate return to earth following separation.
On the trip of Apollo 16 to the Moon an electro­
phoretic separation of different inert latex parti­
cles was achieved at zero gravity. This demon­
strated the feasibility of doing electrophoresis
at zero gravity.
Work is now underway in Buffalo's
immunochemistry laboratory as well as at
NASA to prepare the way for more sophisticated
zero gravity cell electrophoresis experiments.
Explained Dr. van Oss, "Although this approach
awaits the development of continuously
operating space laboratories to be applied
routinely to clinical problems, these pioneering
investigations should open the way for such
applications. •

The "team" discuss progress on electrophoresis of lymphocytes.

President Robert L. Ketter has appointed a five-member Task Force
to study the utilization of University staff, facilities and funds now
devoted to teaching and research in the life sciences. Einstein Profes­
sor Jui H. Wang will chair the Task Force on the Utilization of Life
Science Resources which has been charged with determining whether
the present organizational structure contributes "in an optimal fash­
ion to the accomplishment of our teaching, research and service
missions."
Two Medical School faculty members — Sir John C. Eccles,
Nobel Laureate and distinguished professor of physiology and bio­
physics, and Dr. Om P. Bahl, professor biochemistry — are on the
task force. The other members are Dr. Peter T. Lansbury, professor
of chemistry and Dr. Frank A. Loewus, professor of biology.
Dr. Ketter, in a letter to the Task Force, noted that "The Univer­
sity's organizational chart suggests, at first glance, a possible duplica­
tion or overlap" of resources. He noted that there are eight depart­
ments involved in the study of biology or specialized areas of biology.
There are five departments concerned with chemistry. Pharmacology
is offered in departments located in the Schools of Medicine and
Pharmacy and at Roswell Park Memorial Institute.
Dr. Ketter asked the Task Force to examine the present organiza­
tional structure and answer the question "Are there alternative modes
of organization which might lead to a better utilization of University
resources and a more efficient accomplishment of our objectives?"
No deadline was set for the group, but Dr. Ketter said he wishes
to impress upon its members "the primary importance and urgency
of the problem" and that he hopes the Task Force will present a
report to him as soon as possible. •

Medical School Executive Officer
Dr. Clyde L. Randall, vice president for health sciences at the Univer­
sity since 1970 and acting dean of the School of Medicine since
1971, has been appointed executive officer of the School of Medicine.
Dr. Robert L. Ketter, president, made the appointment on the
recommendation of Dr. F. Carter Pannill, who became vice president
for health sciences on July 1. Dr. Randall will hold the post until
a permanent dean is appointed. An 11-member search committee,
chaired by Dr. Alan J. Drinnan, was appointed in March to find
and recommend candidates for the deanship. No deadline for the
committee has been set, although Vice President Pannill has said
that he would like to have the new dean appointed as soon as possible.
Referring to Dr. Randall's new assignment, President Ketter said,
"We are deeply indebted to Dr. Randall for accepting this interim
assignment with the same dedication he has shown in his key position
as vice president for health sciences during the past three years.
We are most fortunate to have his experience and ability as we launch
a new era for health sciences at this University." •
FALL, 1973

Life Science
Resources

Dr. Edward F. Marra gives final instructions to the graduates.

127th Annual
Commencement

It was traditional. There was the procession of cap-and-gown clad
Doctor of Medicine candidates and faculty, the Invocation, and oathtaking (Maimonides as well as Hippocratic). There was the hooding
and signing of the Book of Physicians where family and friends
individually acknowledged their loved ones. There was the dedi­
cation of the medical/dental school yearbook, MEDENTIAN by the
class to Dr. Jules Constant and his eloquent response. There was
the class president's moving charge to the graduates, as well as recog­
nition for outstanding work through awarding of prizes.
But, added was the graduates' plea to support Dr. Mohamed
Megahed denied tenure and promotion — and the conferring of Mas­
ters and doctor of philosophy degrees to basic sciences candidates
at the School of Medicine ceremonies. •

The processional.

The Medical School had its own
commencement for the first
time in recent years. It was com­
bined with the annual class day
awards. The University had
15 separate Commencement
Ceremonies in May for the first
time. •
24

18 Seniors Honored
Eighteen senior medical students shared 1'5 awards at commence­
ment exercises of the School of Medicine, May 20 at Kleinhans Music
Hall. One, Michael R. Savona, earned three while three others, Wil­
liam J. Ackerman, Robert L. Penn, and Michael A. Sansone, earned
two each.
The awards were presented to the following by Dr. Clyde L.
Randall, acting dean of the School of Medicine and vice president
for Health Sciences who also conferred 115 MD degrees to the seniors.
To basic sciences graduate students 43 PhD degrees, 24 Master of
Arts degrees, and four Master of Science degrees were awarded.
Alpha Omega Alpha (National Honorary Society) — William J. Ackerman, Dana E. Jock, Nancy L. Lieberman, Charles J. McAllister, Robert
L. Penn, Melvin R. Pratter, Michael R. Savona, Stephen A. Smiles,
Richard A. Spector, Dennis E. Stempien.
Thesis Honors — Daniel C. Wistran
U p j o h n Award (zeal, diligence, application in study of medicine)
— Maxine D. Hayes
B u f f a l o S u r g i c a l Society Prize in Surgery (academic excellence) —
Dana P. Launer
David K . Miller Prize in Medicine (demonstration of Dr. Miller's
approach to caring for the sick — competence, humility, humanity)
— Michael A. Sansone
Gilbert M. B e c k Memorial Prize in Psychiatry (academic excellence)
— James S. Marks
Philip P. Sang Memorial A w a r d (efficiency in practice of medicine,
dedication to human values) — Michael R. Savona
Morris Stein Neural Anatomy Award (excellence in neural anatomy)
— Michael V. Murphy
Maimonides Medical S o c i e t y Award (application of basic science
principles to practice of medicine) — William J. Ackerman
Hans J. Lowenstein Award in Obstetrics (academic excellence) —
Michael R. Savona
B e r n h a r d t a n d Sophie B. G o t t l i e b Award (combination of learning,
living, serving) — Michael A. Sansone
M a r k A . Petrino Award (demonstrated interest, aptitude for general
practice of medicine) — Daniel J. McMahon
Lieberman A w a r d (interest, aptitude in study of anesthesiology) —
Steven T. Pugh
Emilie D a v i d Rodenberg Memorial Fund (academic excellence in
study of diabetes, its complications) — Kenneth L. Gayles
Dr. Heinrich Leonhardt Prize in Surgery (academic excellence) —
Robert L. Penn •

FALL, 1973

25

Linda Young, Dr. Cummiskey

Michael Sansone, class president all four
years, said "complete and competent medical
care is our prime motivation . . . that he (Dr.
Megahed) has literally devoted mind/soul to
educating students, caring for patients."

"I have always used teaching as a way
to make learning easier /or myself . . .
I have learned much from teaching
you," Dr. Jules Constant said. He was
honored in the Medentian.

Graduate students receive their master's and Ph.D. degrees.

Five black students were among the 115 medical graduates. Only six black physicio
graduated from the Medical School before 1967.

Roger Simon receives congratulations
from William C. Baird, chairman of the
University council.

Charles Anderson, Dr. Thomas Cummiskey

Kenneth Gayles, Dr. Cummiskey

THE BUFFALO PHYSICIAN

«

In a commencement luncheon address on the tenth floor of Goodyear
Hall, President Robert L. Ketter said that the 1973 graduating class
of 5,853 students is the largest in the school's history and brings
to a total of 71,928 the number of graduates of the school since
it was founded in 1846. More than half of that total, 38,767, have
graduated in the eleven years U/B has been a member of the State
University of New York. As a private institution, the University
graduated only 33,161 in the 116 years from 1846 to 1962.
Dr. Ketter made special note of the 97 Equal Opportunity Program
students receiving their degrees, 23 of whom have achieved honors.
16 were graduated cum laude, 5 magna cum laude and 2 summa
cum laude. One of the summa cum laude students maintained an
academic average of 3.8 of a possible 4.0. The Equal Opportunity
Program was initiated at U/B for underprivileged students following
the assassination of Martin Luther King in 1968. This year's class
is the program's second full graduating class.
In analyzing the total number of 1973 U/B graduates, Dr. Ketter
said that 484 doctorates, 1,290 masters, 3,664 bachelors and 45
associate degrees are being awarded. 115 medical doctors and 75
dentists were graduated, while the School of Law awarded 180 Juris
Doctor degrees. The graduates came from 49 New York State counties,
18 states, and 35 foreign counties.
Commenting on U/B's decentralized commencement ceremonies
initiated this year, Dr. Ketter described "preliminary opinions" as
"favorable." He said that the 15 separate ceremonies attracted more
than 13,000 friends or members of the families of graduates and
a higher proportion of graduates than participated last year.
Dr. Ketter concluded his remarks by citing seven members of
the U/B faculty and staff retiring this year after a combined University
service of 225 years. They are: Dr. Gregory Breit, distinguished profes­
sor of physics; Dr. Raymond Ewell, former vice president for research;
Miss Dorothy M. Haas, former director of Norton Hall; Dr. John Horton, professor of American history and former department chairman;
Dr. A. Margaret Larsen, former chairman of functional nursing; Dr.
Harriet F. Montague, professor of mathematics, and Dr. Oscar A.
Silverman, director emeritus of university libraries and former Eng­
lish Department chairman. •

Drs. S. Mouchly Smali, Cedric Smith, Edward Marra.

FALL, 1973

27

5,853 Graduates

Drs. EJJison and Ronald Rohe, a Fellow
in oncology and hematology, examine
a patient.

T,

A New Medical
Oncology Unit

REATMENT, TEACHING AND RESEARCH are the main thrusts of the
first Medical Oncology unit at the E. J. Meyer Memorial Hospital.
Here, Dr. Rose Ruth Ellison and a team of oncologists, fellows, and
residents will study and treat the gamut of neoplastic diseases seen
in the outpatient service and in the hospital. They will also provide
consultation and work with physicians and surgeons treating patients
who have neoplastic diseases.
"Our group," says Dr. Ellison who is an associate professor of
medicine, "will be particularly involved with patients who have
recurrent disease and those with neoplastic problems who are no
longer amenable to surgical or irradiation treatment."
The investigator, who has over 20 years of experience in clinical
cancer research, drug trials, clinical pharmacology in leukemias,
lymphomas, and solid tumors, is planning a joint medical oncology/hematology training program where medical house staff and
fellows will study the natural history of these diseases. "We want
them to learn about methods of specific and supportive care for
these patients," Dr. Ellison, who is also the hospital's associate direc­
tor of medicine, said. The fellows will also participate in clinical
pharmacologic studies that must precede the therapeutic evaluation
of new drugs in patients with cancer.
For medical students, there will be a joint medical oncology/sur­
gery approach to their cancer teaching program. The medical
oncology team will join the surgical group headed by Dr. Gerard
Burns, who is associate professor of surgery, in clinical conferences,
discussion of patient care and didactic lectures for the student who
will have access to cancer teaching materials. For those seniors who
want a more concentrated approach, there will be the opportunity
of an elective in the medical oncology unit.
Says Dr. Ellison, "Before we give any drug to a patient, we
want to complete a wide range of clinical and laboratory studies
to arrive at a profile of a tumor in that patient. We then treat according
to protocols that take advantage of the chemical structure and bio­
chemical activity of the drugs involved. Such protocols standardize
the routes and schedules of drug administration, the measurement
of the effects of a compound on the tumor in a particular disease,
the kinds of patients to be treated, and the methods for analyzing
the effects. We have developed a standardized type of record keeping
that involves an enormous amount of cooperation among national
investigators as a means to learning more about clinical cancer and
improving available treatment."
28

THE BUFFALO PHYSICIAN

Dr. Ellison, a graduate of Columbia University College of Physi­
cians and Surgeons, will continue as executive officer of an inter­
national cooperative group, Acute Leukemia Group B, which is active
in evaluation of new chemotherapeutic methods in leukemias,
lymphomas, and solid tumors. In this research group, funded by
the National Cancer Institute and headed by Dr. James F. Holland,
research professor of medicine and chief of Medicine A at Roswell
Park Memorial Institute, are clinical and laboratory scientists from
over 50 hospitals and six countries who study the results of treatment
in more than 1500 patients a year. Such patients, are treated under
formal controlled protocols with standardized methods of treatment,
record keeping and evaluation. Clinical research in such cooperative
studies, points out Dr. Ellison, has already led to development of
markedly improved treatment for acute leukemia in children. Less
marked, but definite improvement in available treatment for acute
leukemia in adults, is now being seen.
"While chemotherapy alone is curative only in some patients
with choriocarcinoma, Wilm's tumor and Burkitt's lymphoma (and
hopefully in some children with lymphocytic leukemia), it is pallia­
tive in numerous other situations," says the former associate chief
of Medicine A at Roswell Park Memorial Institute and staff member
at Memorial Hospital and Sloan-Kettering Institute in New York City.
"It is expected that large-scale study of combinations of drugs
— alone or in combination with other modalities of therapy — will
lead to considerable improvement in the treatment of other cancer,"
she said.
Dr. Ellison is a member of the Advisory Committee on Clinical
Investigation of the American Cancer Society, The Cancer Clinical
Investigation Review Committee of the National Cancer Institute,
and the National Board of Trustees and the Medical and Scientific
Advisory Committee of the Leukemia Society of America, Incor­
porated. She is also secretary-treasurer of the American Society of
Clinical Oncology, and will continue to be a consultant at Roswell
Park. Dr. Ellison's husband, Dr. Solon A. Ellison, is professor and
chairman of the Oral Biology Department in the Dental School at
the University. •

Dr. Edward S. Hender­
son is the new chief of
Medicine A at Roswell
Memorial Institute. He
served as head of the
Leukemia Service
Department, National
Cancer Institute,
Bethesda, Md., since
1965. Dr. Henderson re­
places Dr. fames F. Hol­
land who joined the
staff of Mt. Sinai Hospi­
tal, New York City.

Dr. Stephen AJpert, Dr. Ronald Rohe, Dr. Ellison, Stephen Yerkovich, 3rd year medical student, Donald
Younkin, 3rd year medical student, and Dr. Richard Bettigole, associate professor of medicine, examine
a patient.

Summer Fellowships
For 49 medical students, studies were not over when the spring
session ended in May. Through the unique opportunity of $750 to
$1000 fellowships, 30 freshmen, 16 sophomores, and 3 juniors are
spending a ten-week period in a new or continuing clinical or
research experience.
In reviewing applications received from medical students that
outlined proposed research or clinical projects under specific precep­
tors, the six member summer fellowship committee (three from basic
sciences, an equal number representing clinical departments) under
chairman Dr. Carl J. Bentzel awarded nine $1000 fellowships to con­
tinue outstanding projects begun earlier. Through this program, the
associate professor of medicine hopes to encourage medical students
to continue project-oriented research on their own time during their
four years of medical school.
Pointed out Dr. Bentzel, "some of these projects are as carefully
planned and pursued as research projects by senior faculty." Receiv­
ing these special stipends were Jack Cukierman, John Hedger, Lynne
Hochberg, Michael Nakao, Mary Roembolt, Ian S. Brown, James Burdick, Nina Kostraba, and Robert Weiss.
Over half of the students (31) are working on projects involving
basic medical sciences, clinical research as well as in the study
of health care services. The remaining 18 are furthering their educa­
tion through preceptorships in the clinical field.
Most (43) remain in Buffalo to work in University research
laboratories and at Roswell Park Memorial Institute, in local hospitals
or in health clinics located in the county. Two traveled to Ecuador
and Colombia (South America) to gain insight into medical practices
there while one is spending the summer at a Brooklyn Medical Center,
another at the University of Rochester.
$1,000 Continuing Fellowship
Local
Project
Cukierman, Jack '75
Testing implanted device for peritoneal dialysis
Hedger, John '75
Hochberg, Lynne '75
Nakao, Michael '75
Roemboldt, .Mary '75
Brown, Ian S. '74
Burdick, James '75
Kostraba, Nina '75
Weiss, Robert '76

Effect of antiarrhythmic drugs on digitalis-induced
atrial arrythmias
Morphological study of two neurosecretory systems related
to salt/water balance in Lebistes Reticulatus
Perception/processing of stimuli alternating between
receptive surfaces in audition/somesthesis
AC current response to altering epithelial morphology
Sensitization of human lymphocytes to autologous
malignant cells
Induction/treatment of Wilm's tumor in Wistar/Firth rats
Nonhistone proteins/gene regulation
Enhanced sensitization of cultured human lymphocytes to
autologous malignant cells

CLINICAL
Bishop, William C. '76

Experience in a mental health emergency clinic

Gitterman, Benjamin '76

Community medicine

Goldfield, Norbert '76

Societal response to managing drug abuse

30

Jewish Hospital/Medical Ctr.,
Brooklyn, Dr. B. Levowitz
E.J. Meyer Hospital, Dr. S.
Wittenberg
Anatomical Sciences, Capen Hall,
Dr. E.R. Hayes
Psychiatry, 2211 Main Street,
Dr. S. Axelrod
Veterans Hospital, Dr. C. Bentzel
Roswell Park Mem. Institute,
Dr. J. Mitchen
Roswell Park Mem. Institute,
Dr. G. Murphy
Biology dept., Dr. T. Wang
Roswell Park Mem. Institute,
Dr. J. Mitchen
E.J. Meyer Hospital,
Dr. M. Gerstenzang
Jesse Nash Health Center,
Dr. A. Goshin
E.J. Meyer Hospital, Dr. C.
D'Amanda
THE BUFFALO PHYSICIAN

Kramer, Stanley J. '76

General preceptorship in a state school

Krawczyk, Justine A. '76

Experience in treatment of alcoholism

Krypel, Geraldine '76

Community health care/delivery

Lichtenstein, Howard '76

Preceptorship in geriatrics

Pohl, Melvin I, '76
Ritter, Thomas L. '76

Child psychiatry
Rural clinic/hospital experience

Russell, Keith '74

Evaluating infants born to methadone dependent mothers

Shriro, Linda '76
Tardino, John A. '76

Child psychiatry
Rehab, approach to physically handicapped/retarded children

Weiss, Barry D. '76

Rehab, approach to physically handicapped/retarded children

RESEARCH
Local
Anderson, Serafin C. '76
Bartkowski, Henry '74
Cohen, William I. '75
Bowe-Anders, Constance '76
Ferraras, Richard '75
Friedes, Francine E. '76
Fogel, Marshall A. '76
George, Donald E. '76
Horner, Douglas '76
King, Janet '76
King, Peter '76
Kulick, Kevin B. '76
Lazoritz, Stephen '76
Neander, Michael J. '76
Nocek, Marie A. '76

Project

Compare blood pressure measurements in low birth weight
infants by three different methods
Electron microscopic studies of human ependymal linings
in hydrocephalus
Idiopathic hypopituitarism
Postnatal dev/funct. differential of mammalian retina
Antibody response to specific bacterial infections
Relating ob/gyn patient's sex edu/attitudes on
menustration/ovulation/pregnancy to socio/econ
status
Estrogen antagonism of activating effect of androgens
on prostatic membrane ATPase
Isolate/characterize hexoseaminidase A; invest.
Tay-Sachs disease
Factors affecting cadmium distr/excretion in rat
Evaluate psychiatric problems in patients undergoing
radical surgery for cancer therapy
Specimen preparation for gross human anatomy
Study knowledge/attitudes on pre/postabortion counseling
of male
Investigate relationship between pharmacokinetics of anti­
bacterial agents/clinical success of drug therapy in
urinary tract infection of pediatric patient
Prepare prosected specimen for gross anatomy

Samuel, Agnes L. '76
Schenk, Carlos '76

Study ligation of intestinal lymphocytes; effect on serum
lipids
DNA content of normal/abnormal cells in retina of rat
Failure of prenatal masculinization

Szfler, Hanley J. '75

Renal clearance of digoxin used as guide to drug therapy

Wagman, Bernard '76

Anesthesia procedures, respiratory physiology

Warner, Natalie '75
Zak, Thaddeus A. '76

Effect of 6-aminonicotinamide on dev. nervous system/rat
Physiologic function of superoxide dismutase; a "new"
enzyme

Rowland, Michael C. '75

West Seneca State School, Dr. L.
Huzella
Veterans Hospital, Dr. L.
Lewandowski
Lackawanna Community Health Ctr.,
Dr. A. Goshin
Buffalo State Hospital, Dr. N.
Winkelstein
Children's Hospital, Dr. T. Anders
Concord Medical Grp, Springville,
Dr. C. Rodgers
E.J. Meyer Hospital, Dr. C.
D' Amanda
Children's Hospital, Dr. T. Anders
Children's Rehab. Center,
Dr. E. Warner
Children's Rehab. Center, Dr. D.
Kerr-Grant

Children's Hospital, Dr. G.
Ciacoia
Anatomical Sciences (Capen Hall
Neurosurgery (Meyer), Drs. J.C.
Lee, L. Bakay
Children's Hospital, Dr. T.Aceto
Neurosensory Lab., Dr. W. Noell
Children's Hospital, Dr. E. Neter
E.J. Meyer Hospital, Dr. L.
Hevizy
Veterans Hospital, Dr. W.E.
Farns worth
Children's Hospital, Dr. R.
Davidson
U. of Rochester, Dr. J.C. Smith
Roswell Park Mem. Institute,
Dr. M. Plumb
Anatomic Sciences (Capen Hall),
Dr. J.C. Lee
Erie County Medical Group, Mrs.
E. Kaiser, C. Lechner
Children's Hospital, Dr. T.Aceto
Anatomical Sciences (Capen Hall),
Dr. J.C. Lee
Veterans Hospital, Drs. D. Dean,
A. Gage
Neurosensory Lab., Dr. W. Noell
Children's Hospital, Dr. H.
Meyer-Bahlburg
Millard Filmore Hospital, Dr.
F. Kauffman
E.J. Meyer Hospital, Dr. R.
Markello
Pharmacology Dept., (Capen Hall),
Dr. F. Kauffman
Biochemistry Dept., (Capen Hall),
Dr. M. Ettinger

FAMILY PRACTICE (arranged by Dr. James R. Nunn)
Cassiano, Coley J. '75
Dr. Robert Haines, 3435 Bailey Avenue
Franklin, Hall A. II '75
Dr. Herbert E. Joyce, 3435 Bailey Avenue
Zinn, Steven '75
Drs. E.R. Haines, J. Nunn, Deaconess Hospital
INTERNATIONAL
Burke, Alan M. '76
Trautman, Paul D. '75
FALL, 1973

Clinical Urdess, Guayaquil (arranged
by Dr. E. Beutner)
Ibaqune, Columbia

Medical practice in Ecuador
Clinical preceptorship in a Colombian hospital

31

Drs. Cohen and Bigazzi go over research results.

Cellular
Immunity

Dr. C o h e n h a s contributed over
50 scientific articles and is
editor of three journals in his
field. He has co-authored a
book with Dr. Robert T. McCiuskey of Harvard University, who
served as chairman of path­
ology at UB from August 1968
to September 1971 on Mechan­
isms of Cell-Mediated Immun­
ity. It d e t a i l s v a r i o u s a r e a s o f
immunology mentioned in this
story. •
32

There is a diverse approach in Buffalo to the
study of a rapidly-growing field of immunologic
research called cellular immunity. A team of
investigators with Drs. Stanley Cohen and
Takeshi Yoshida, are looking at a specific class
of immune reaction that is mediated by living
cells called lymphocytes rather than by anti­
bodies. This immunologic response functions
as an enhancing system. For it makes inflamma­
tory cells work more effectively at sites where
antigen is present in the body.
Responsible for this activity are factors
known as lymphokines. Soluble substances pro­
duced by sensitized lymphocytes, they also pro­
duce profound effects on many other kinds of
cells. The first lymphokine to be discovered,
migration inhibition factor (MIF) by Dr. John
David of New York University and Dr. Barry
Bloom of Albert Einstein University, is now
under study in the laboratories of Dr. Cohen.
What the professor of pathology and former
acting director of The Center for Immunology
basically wants to do "is to identify new
lymphokines, characterize them in relation to
one another, and explore the range of their bio­
logical activity."
This approach was pursued in his studies
with Dr. Hidekichi Sonozaki on the effects of
lymphokines on inflammatory exudate cells
within the peritoneal cavity of guinea pigs. Not
only did they show that MIF (previously defined
only in vitro) could function within the intact
animal but that a specific kind of lymphocyte,
called a T-cell, was responsible for the reaction.
Also pinpointed in some lymphokines was
another important property known as chemotaxis. These are chemical agents which attract
living cells.
These findings led to a series of experi­
ments on chemotaxis of various inflammatory
cells with Dr. Motomichi Torisu and University
of Connecticut's acting pathology chairman Dr.
Peter Ward. The investigators were the first to
THE BUFFALO PHYSICIAN

discover the mechanism by which eosinophils
are attracted to immunologic reactions in cer­
tain allergies and autoimmune diseases. This
mechanism involves the formation of a sub­
stance called ECF by sensitized lymphocytes.
Said Dr. Cohen who is a Columbia College
of Physicians and Surgeons graduate (1961),
"during our investigations we continually ask
whether substances under study have any real
significance inside the body. While it is obvi­
ously worthwhile to describe a factor affecting
cells in a test tube or tissue culture system, until
we know that it functions in vivo we have no
proof that it is useful in protection against
disease."
He cited a lymphokine discovered through
a biophysical technique pioneered by micro­
biologist Dr. Carel J. van Oss that affects the
surface tension of inflammatory cells. However
it awaits the defining of an in vivo system to
prove whether it may play an important role
in modifying inflammatory cells by making
them more efficient scavengers.

Dr. Yoshida checks a lymphocyte culture.

FALL, 1973

Dr. Cohen "asks" the results of a computer program.

Because of continued concern with human
applications, the investigators, joined by Dr.
Takeshi Yoshida, turned to studies of mediator
substances which could be directly extracted
from immunologic reactions. They showed that
many factors previously found only in cultures
of sensitized lymphocytes could be detected in
tissue extracts as well. "We seem to have
established a link in the chain of events," said
Dr. Cohen, "which begins with the 'switching
on' of a specific lymphocyte and ends with
an immunologically-induced inflammatory
reaction."
The lymphokines provide one route by
which the immune system serves a protective
function. It is especially important in diseases
involving viruses, fungi, and certain intra­
cellular parasites. However the 36-year old
immunopathologist is quick to point to similar
factors made by other kinds of cells in the body
that also play a role in resistance to disease.
Their production is not dependent upon the
immune system. He pointed to interferon pro­
duction as an example.
Could cells infected by viruses be induced
to produce substances which function like
lymphokines as well as interferon? asked Drs.
Cohen and microbiologist Dr. Tom Flanagan.
With Drs. Peter Ward and Takeshi Yoshida they
showed that mumps virus and Newcastle dis­
ease virus could induce nonlymphoid cells in
tissue culture to produce MIF as well as chemotactic substances. I
33

cr

A group of investigators check a radioactive immunologic assay.

Further investigations with oral biologist
Dr. Robert Genco showed that mumps infection
of monkey parotid glands led to the release of
similar factors within the glands themselves.
Extracts of these glands, when injected into nor­
mal tissues, produced identical inflammatory
reaction to those in infected glands.
Encouraged by results in infectious dis­
eases, the Buffalo team turned to a study of vari­
ous malignant states. With Dr. Pierluigi Bigazzi,
they showed that certain oncogenic (tumorproducing) viruses could induce infected cells
to make lymphokine-like substances. Moreover,
in a series of experiments with Dr. Richard
Zeschke lymphokines themselves were found
able to modify the behavior of tumor cells.
In cooperative studies with Drs. Ben Fisher
of the Veterans and Richard Bettigole of the
Meyer Hospitals, patients with lymphoma and
leukemia are being studied for similar effects.
Already demonstrated is the appearance of MIF
in the sera of some of these patients at certain
stages of their disease. Future studies are
34

planned by Dr. Cohen to correlate this promis­
ing lead with the extent of malignant disease
or response to therapy.
These diverse multidisciplinary ap­
proaches to the study of mechanisms of inflam­
mation and immunity involve pathologists,
internists, surgeons, and microbiologists. Even
computers are members of this informal "team."
Continuing an interest he developed as a resi­
dent at the Massachusetts General Hospital and
while training in immunology under Dr. Baruj
Benacerraf at New York University, Dr. Cohen
is performing computer simulation studies on
the above phenomena. Much of the work has
been done with Martin Milgrom, a medical stu­
dent at Columbia University
This collaborative approach extends to
training programs in which Dr. Cohen
participates such as basic pathology course, an
advanced elective in computer programming,
W.H.O.-sponsored
immuno methodology
courses, and a series of international convoca­
tions sponsored by The Center for Immunology.



THE BUFFALO PHYSICIAN

Mr. Marshall G. Ause, director of management and planning for
the Chicago-based American Hospital Association (since 1968) is
the new director of the E.J. Meyer Memorial Hospital. He assumed
his new duties August 1.
A native of Minnesota, Mr. Ause has 27 years of experience
in hospital administration. He holds a master's degree in hospital
administration from the University of Minnesota and received his
bachelor's degree from St. Olaf College, Northfield, Minnesota. He
has held top level administrative posts at military hospitals in North
Little Rock, Arkansas and St. Cloud, Minn., at civilian hospitals
in Orange, Calif., Brooklyn, N.Y. and Milwaukee, Wisconsin.
Mr. Ause has served on the advisory council for the Hospi­
tal Administration course at the University of Minnesota's School
of Public Health and has' lectured at several West Coast colleges
and universities. His responsibilities in Buffalo will include planning
the operation of the county's new $87.5 million Comprehensive
Health Center, under construction adjacent to the Meyer.
"I was attracted to this position by the high quality of medical
care, the dedicated hospital advisory board, the new facility under
construction and the hospital's affiliation with the University Medi­
cal School. Also I think Buffalo will be a very attractive place to
live." •

Ause Heads
Meyer Hospital

Dr. Donald Larson Joins Faculty
Dr. Donald A. Larson has been named associate vice president for
health sciences and professor of biology. Since 1959 he has been
professor of botany and director of education for health professions
at the University of Texas at Austin.
Dr. Larson, a native of Chicago, received his bachelor of science
degree (1953) from Wheaton College and master of science (1955)
and doctor of philosophy (1959) degrees from the University of
Illinois.
He received a Teaching Excellence Award from the University
of Texas Students' Association in 1966. He is a member of the Botani­
cal Society of America, American Society of Cell Biology and Sigma
Xi. He has authored more than 30 papers published in professional
journals. •
FALL, 1973

35

Dr. Larson

Two Health Sciences faculty members were cited for their dedication
to teaching and concern for students in the Medical/Dental schools'
student yearbook, Medentian. Dr. Gerard Wieczkowski, Jr. was hon­
ored by the dental students and Dr. Jules Constant by the medical
students.

Dr. Constant

Medentian Honors
Two Professors

Dr. Wieczkowski

Dr. Wieczkowski, 31, is assistant professor of operative and pub­
lic health dentistry. He joined the dental faculty in July 1969 as
a teaching fellow following graduation from SUNYAB dental school.
While a dental student he served as senior class president, editorin-chief, Medentian, was a member of the Med/Dent Student Council,
on the dean's search committee, faculty conference on education,
and received the senior class alumni award. As a faculty member
he has lectured extensively throughout the state on preventive
medicine among other subjects, and has been deeply involved in
both student/faculty relations. His current research centers on
developing a protocol to study anterior restorations and a staff study
of pit/fissure sealants.
Dr. Constant, 51, is clinical associate professor of medicine who
has been on the faculty since 1962 when he was instructor in
medicine. The Canadian-born cardiologist received his MD degree
from the University of Toronto in 1953, interned at Washington,
D.C.'s Central Dispensary and Emergency Hospital, followed by a
residency in general practice in Arizona and a year of general practice
in Canada before resuming his training in the field of internal
medicine in San Diego's Mercy Hospital. A year in private practice
there preceded a fellowship in cardiology in London with Dr. Paul
Wood. He returned to Buffalo in 1960 to spend the next four years
as a research fellow in cardiology at Buffalo General Hospital. He
he authored several articles and two books, Bedside Cardiology and
Learning Electrocardiography, (a complete course).
In their dedication to Dr. Wieczkowski, the dental students said
"in the four short years that Dr. Wieczkowski has been on our clinical
staff he has shown a talent for teaching that has gained him the
respect and admiration of those he has guided. Only when concern
for the student and concern for the design of his educational experi­
ence are held primary, can the teacher most effectively achieve his
goals. Dr. Wieczkowski is always available and approachable whether
in or out of the clinic. He has taken active part in committees of
faculty-student interaction where his unique background as recent
graduate and instructor make him sensitive to the positions of both
parties. In appreciation for his work and desire to serve us, we the
Class of 1973, make this dedication."
In their dedication to Dr. Constant, the medical students said
"it is with great pleasure that the Class of 1973 dedicates this yearbook
to Dr. Jules Constant . . . represents a very rare breed of medical
educator — one who literally spends all his time with medical stu­
dents. There are very few members of the Class of 1973 who did
not attend and thereby profit from his weekly sessions in cardiac
physical diagnosis and electrocardiography during our sophomore
year. And during any month of the school year at the Buffalo General
Hospital one can see several senior students trailing behind him
as they head for the coffee shop and a discussion or to one of the
floors for a consult. It is his enthusiasm as a teacher and his neverending willingness to inconvenience himself and his family for the
sake of students that has earned our deepest respect and gratitude."
36

THE BUFFALO PHYSICIAN

A1921 honor graduate of the Medical School was among eight leaders
in education, business and politics honored in June at the 34th annual
installation and awards dinner of the University's Alumni Associa­
tion. Dr. Bernhardt S. Gottlieb received the Distinguished Alumni
Award. He is still in psychiatric practice in New York City and
teaches at the State University Downstate Medical Center and New
York University.
Dr. Gottlieb interrupted his long practice for a three-year
residency at the New York State Psychiatric Institute. He has also
earned a bachelor's degree in social sciences from City College of
New York, and a doctor of medical science in psychiatry from Colum­
bia University College of Physicians and Surgeons.
Bernhardt Gottlieb has been president of Metropolitan New York
City Medical Alumni of U/B, a member of the General Alumni Board
and donor of an award which is given annually to a U/B medical
graduate who combines living in the community and academic abil­
ity. He maintains a lively interest in alumni affairs and in particular,
the Bernhardt S. and Sophie B. Gottlieb Psychiatric Library Fund.
Mr. Gerald C. Saltarelli, chairman and president of Houdaille
Industries, Inc., and Mr. Charles K. Bassett, businessman and
philanthropist, received the Capen and Cooke Awards. Mr. Morley
C. Townsend, immediate past president of the alumni association,
received the President's Award from Dr. Robert L. Ketter. Four others
— Hon. Earl W. Brydges, Hon. Charles S. Desmond, Dr. Anthony
S. Gugino, and Dr. Olive P. Lester — received Distinguished Alumni
Awards. •

Dr. Gottlieb
Honored

Dr

Future Alumni Receptions
Since its inception in July' 1969 as a part of the annual alumni
program, 611 alumni have attended cocktail receptions hosted by
the Medical Alumni Association. Mr. David Michael, director of
medical alumni affairs, said that the following receptions planned
for 1973-74 are open to all alumni, faculty and friends of the Medical
School.
American College of Surgeons
October 15-19, 1973 — Chicago, Illinois (Alumni Reception
October 16, 1973 at Conrad Hilton)
Medical Society of the State of New York
February 24-28, 1974 — New York City Americana Hotel
American College of Physicians
April 1-5, 1974 — New York City
American Medical Association
June 22-27, 1974 — Chicago, Illinois
American College of Surgeons
October 21-25, 1974 — Miami, Florida, Fountainbleau Hotel •
FALL, 1973

37

C nt+Hoh

JUNIOR MEDICAL STUDENTS are now coming

For Steven Yerkovich who visits a patient in the home,
"the home setting benefits both patient and physician. At
least psychoiogically the patient is much better off."

New Experience
for Juniors

38

face-to-face with some of the major social prob­
lems that medicine is up against in health care
for the poor outside of the hospital setting. As
part of their medicine elective, students may
now spend a full week getting indepth exposure
in the E.J. Meyer Memorial Hospital's alcohol­
ism program, hemophilia or drug addiction cen­
ters (one is at the Sisters Hospital also). Or they
may be assigned to either the Lackawanna or
Allentown clinics or to the University Health
Center.
"Some students," pointed out Dr. Leonard
Katz who is coordinator of third year medicine
and heads this new learning experience for
juniors, "are even selecting their own rural prac­
titioners in order to become familiar with a dif­
ferent set of social problems."
For students assigned to the Lackawanna
Clinic, there is not only an opportunity to help
care for patients but to learn something of their
socio/economic backgrounds during home vis­
its arranged by a family health worker. Agreed
assigned students "the home setting benefits
both patient and physician. At least psycho­
logically the patient is better off." But they
debated whether better health care can be pro­
vided in the home.
One student saw this type of medical
experience as the "up and coming form of medi­
cine," and the Lackawanna Clinic as one of the
"few places where we as students can get this
more personal kind of experience" that he
would have liked to last longer than a week.
Others felt a week to be sufficient during the
junior year.
THE BUFFALO PHYSICIAN

Some students enjoyed dealing with the
younger population "not sick enough to be in
the hospital but too ill to remain in their rooms."
At the University Health Service they witness
a "real change from the wheelchair or bedridden
hospital patient."
Pointing to greater student responsibility
was Dr. Luther Musselman who heads the Ser­
vice program for "illness here is not so serious."
Students often make the decision as to what
to prescribe. He felt the experience of all 13
students rotating through the service last year
to be satisfactory to all concerned.
Starting in the fall, each new week's group
of students will hear a seminar arranged by
Frank Corbett, Director of Urban Affairs at the
University who has helped Dr. Katz plan this
learning experience on health care for the
poor. •

Frank Corbett and Dr. Katz review plans for the fall program.

John Pinneila exam­
ines a patient's foot
during a home visit
with family health
worker Rosie Reves
watching.

FALL, 1973

39

JUNIORS

Dr. Carol Segal who runs Lackawanna Clinic program and Michaei Sdao see
patient during ciinic hours.

Keith Russell examines a student in the University Health Center as Dr. John
B. Benny looks on.

40

THE BUFFALO PHYSICIAN

Continuing Medical Education
Nine Continuing Medical Education Programs are scheduled during
Fall, 1973, according to Mr. Charles Hall, director of continuing
medical education. Dates, titles and chairmen of the programs are:
September 6

—Arrhythmias, Dr. Jules Constant, clinical associate
professor of medicine.

October 2-3

—Human Sexuality, Dr. Norman Courey, clinical
assistant professor of Ob/Gyn.

October 11-12 —The Future Role of the State Hospital (sponsored
by Division of Community Psychiatry, CME
assisting), Dr.Jack Zusman, professor of
psychiatry.
October 25
—Hypertension (with Ciba Pharmaceutical), Dr.
Charles M. Elwood, clinical associate profes­
sor of medicine..
October 29-31 —Computers in Clinical Practice (sponsored by
Journal of Clinical Computing, CME assist­
ing), Dr. Elemer Gabrieli, clinical assistant
professor of pathology.
November 15

October 30
November 6
(Evening)
December 4-5

—Evolving Patterns in Community Health, Dr.
Henry P. Staub, associate professor of
pediatrics.
— Today's Management in Pulmonary Disease, Dr.
John W. Vance, clinical associate professor of
medicine.
Gynecological Surgical Techniques, Dr. David
Nichols, clinical professor of Ob/Gyn and Dr.
Vincent J. Capraro, clinical professor of
Ob/gyn. •

Twenty-three alumni, wives, residents, faculty and guests
attended the American College of Physicians alumni reception at
the Conrad Hilton Hotel, Chicago, April 10. Mr. David Michaels,
director of medical alumni affairs, was the host for the reception.
Those attending from Buffalo were: Doctors George and Mrs.
Bauemiller, M'59; Ron Boersma, resident; Marshall and Mrs. Clinton,
MAO; John McConville, resident; Thomas G. Cummiskey, M'48; Sattar Farzan, faculty; Merrick Fisher, resident; Mahendra Mirani, facul­
ty; James Morris, resident; Bernard Norcross, M'38; Raymond and
Mrs. Partridge, faculty; Sheldon Schwartz, resident; Kamal Tourbaf,
faculty. Also — Paul A. Burgeons, M'36, Warsaw, New York; D.
King, Philadelphia, Pennsylvania, guest; Michael and Mrs. Lippmann, M'70, Morgantown, West Virginia; James F. Stagg, M'47, Tuc­
son, Arizona; Jack and Mrs. Sternberg, M'72, Cleveland, Ohio. •
FALL, 1973

41

Chicago
Reception

Mothers sign in with their children.

West Side
Health Center

Adequate health care for every person living
on Buffalo's West Side. That is the motto of
the West Side Health Center at 17 Pennsylvania
Street, according to Mr. Ira Stohl, program
coordinator. Mothers with their children flock
to this outpatient clinic, located in an apartment
house development area.
It is here that a group of spirited health
professionals (physicians, dentists, nurses,
medical students and other volunteers) are
working to bring better health care to residents
of the area. The Center started as the AllentownLakeview Community Health Center on 273
Maryland Street on February 1, 1972.
The Center's main source of income is the
annual March on Hunger. In 1972 the Center's
share was $6,700; in 1973 $5,000 (estimated).
There are three free clinics twice a week
— well-baby, maternity and dental. There are
other programs to combat lead poisoning, pro­
vide immunization and test for tuberculosis.
The free dental clinic is available twice a week
in the Rath Building. The Erie County Health
Department provides the dentists.

The children entertain themselves.

Rosemary McCarthy, a public health nurse, visits
with a mother at the baby clinic.

42

THE BUFFALO PHYSICIAN

Helen Stephenson, a public health nurse, makes a few notes.

Dr. J. Bhattacharyya examines a youngster.

Perhaps more important, the center is will­
ing to take on any number of problems that con­
front individual residents of the area. If the
Center can't provide a certain health service,
it has a list of hospitals and clinics that can.
This means providing transportation for neigh­
borhood residents who can't get to the hospitals
or physicians' offices. Sometimes it means pro­
viding interpreters in Spanish and Italian to go
along to hospitals and clinics with people who
don't speak English well, to help them fill out
forms, to stay with them if necessary until they
receive the help they need. It even means deal­
ing with health-related problems — negotiating
with the gas company about an unpaid bilhj ^
Dorothy Hodges, R.N. of the Erie County Health Department chats with several
youngsters.

The West Side Health Center's
exhibit won third place at Spring
Ciinicai Days.

FUTURE

FALL, 1973

- — - —
Center plans to develop
additional programs will provide compre-,
hansive health care to 10 of the 25 thousand
persons in its target area Community re si -1
d«ntsj^u_controI policies of th^renter
I

Ira Stohl

In the fall of 1969 a group of medical stu­
dents at the University conceived the health
center. The Medical School students were react­
ing to what they felt was a failure on the part
of the profession to recognize and respond to
the need of the communities for communitybased health services. Now the original Center
on Maryland Street is used as an administration
office and for referral services.
Currently there are about 40 Medical
School students involved with the Health
Center. There are six regular volunteers and
about 15 other University students (not medical
students) on the staff.

The Pennsylvania Street clinic cost only
about $400 to equip. There were many dona­
tions from private physicians and the Medical
School, and Buffalo General Hospital. One
pediatrician, about to retire from practice,
donated all his office equipment to the clinic.
There are five examining rooms, a waiting room,
a lab and counseling space in the clinic.
The Erie County Health Department has
assigned one full-time county nurse to the clinic
as well as physicians who conduct the wellbaby clinic every Tuesday morning and the
maternity clinic on Wednesday mornings. •

The reception room.

Betty Coggins with mother and baby.

"4
\ vs.•

s

Looking across the lake from Millersport Highway.

Students will be living on the new North Campus in Amherst in
September. The 920-bed Governor's Residence Hall will be occupied.
The John Lord O'Brian Law and Jurisprudence Building housing
the law school and economics department will also be occupied
in September. There will also be student activity rooms, cafe, library
and bookstore open in this building, according to Mr. John D. Telfer,
vice president for facilities planning at the University.

The bus service that now operates between the South Campus
(Main StreetJ and the Ridge Lea Campus will be expanded to the
new North Campus.

Students Living
on New Campus

In the fall of 1974 the 38-building Joseph Ellicott Complex hous­
ing 3,200 students in a living-learning setting will be ready for full
occupancy. This facility has dormitory rooms, classrooms, faculty
offices, libraries and bookstores.
Five other buildings — education and philosophy, industrial
engineering, biology and pharmacy, physics and chilled water plant
— will be completed before fall, 1975.

The four other Health Sciences Schools — medicine, dentistry,
nursing and health related professions — will remain at their present
location, but will have additional facilities when other segments
of the campus move to the Amherst site.
52

THE BUFFALO PHYSICIAN

1

The electrical station.

Our First Professor of Medicine
Austin Flint (1812-1886)
by
Oliver P. Jones, Ph.D., M.D.
Distinguished Professor of Anatomy

JA.USTIN FLINT was born in Petersham, Massachusetts, 20 October
1812. He was descended from Thomas Flint (ca. 1603-1663) who
came from Derbyshire, England in 1638 and settled in Concord, Mass.
[It was a pleasant surprise to learn that three of my grandchildren,
the Bradford S. Browns, also descended from Thomas Flint through
his great granddaughter, Eunice Flint (1748-1810).] He was fourth
in succession of a medical ancestry. Edwin Flint, his great grand­
father, was a physician in Shrewsbury, Massachusetts. His grand­
father, Austin Flint, was a highly esteemed surgeon in the Army
of the Revolution. Joseph Henshaw Flint, the father, was a dis­
tinguished surgeon of Northampton and afterward of Springfield,
Massachusetts. The younger Austin, received his general education
partly at Amherst and partly at Harvard. He took his degree from
Harvard Medical School in 1833 and at once began to practice in
Boston. In 1835 he married a daughter of N. W. Skillings, Esq., and
the couple had one son, Austin Flint, Jr., born 28 March 1836 at
Northampton, Massachusetts.
When Dr. Flint came to Buffalo in 1836, the antiphlogistic treat­
ment of most diseases was in its zenith. Inflammation was considered
the great pathological element in practical medicine. All the fevers
were regarded as either dependent on local inflammation or as deriv­
ing their gravity from inflammatory complications. He was admitted
to the Erie County Medical Society in 1841 and was appointed health
physician of Buffalo the following year. In the fall of 1843 an epidemic
fever occurred at North Boston (eighteen miles from Buffalo) affecting
twenty-eight of the forty-three inhabitants which proved fatal in ten
instances. Superintendents of the poor were employed by Dr. Flint
to investigate the nature and origin of the disease. He subsequently
published his article in the American Journal of Medical Sciences
and announced his conclusion that typhoid fever is a water-borne

Front flow: Norman F. Graser, Joseph A. Syracuse, Edward J. Zimmerman, Harry A. LaBurt.
Back Row: Leon A. Chadwick, Henry Galantowicz, W. Herbert Burwig, Caryl A. Koch, Donald W. Cohen.

Class of 1923 at Spring Clinical Days
54

THE BUFFALO PHYSICIAN

Class of 1928 at Spring Clinical Days

Front Row: Joseph Rosenberg, Thelma Brock, Bruno Shutkeker, Eugenia Fronczak Bukowski, Harry Spiegelman.
Back Row: George F. Etling, Raymond J. Rickloff, Howard L. Stoll, Richard M. Gardner, Vincent A. Hawro,
Albert J. Voelkle, Clyde W. George, Walter F. King, George N. Guthiel, Floyd C. Bratt.

disease and that it had been transported to North Boston by a sick
traveller from Warwick, Massachusetts. In general treatises on
typhoid fevers, this article is a classic study. He achieved a national
reputation and in 1844 he was appointed Professor of the Institutes
and Practice of Medicine at Rush Medical College. He delivered
a public introductory lecture on The Reciprocal Duties and Obliga­
tions of the Medical Profession and the Public. The occasion was
the first annual anniversary of the organization of the Rush Medical
College. He outlined how far the public is concerned in and responsi­
ble for the complete accomplishment of the legitimate objects and
duties of the medical profession. He spoke about the general public
apathy towards the establishment of medical schools and their finan­
cial support. Some remarks were directed to the legislators regarding
their indifference to making the study of anatomy a legalized pursuit
and the public was told about the value of post mortem examinations.
Since two classes of medical students were present, Flint reminded
them of the necessity for high scientific attainments, elevated princi­
ples of honor, integrity, uniform courtesy — the qualities of a gentle­
man, philosopher and Christian.
Dr. Flint returned to Buffalo in 1845 and founded the Buffalo
Medical Journal which he owned and edited for the next eight years.
His introductory occupied two and a quarter pages. It was written
on 1 June 1845 and a portion of it is quoted here because it so
clearly tells us about the true nature of the man who was destined
to become our first Professor of Medicine.
. . . We would add that the Journal is pledged to no inter­
ests apart from those which relate exclusively to the
progress of Medical Science, and the advancement of
the Medical Profession. It is not instituted for any sec­
tional objects, or partisan views; but to serve as an organj f
FALL, 1973

55

Class of 1933 at Spring Clinical Days

Front Row: Wilfrid M. Anna, Elroy L. Fulsom, Elmer Milch, G. Harold Warnock.
Second Row: Louis Kolbrenner, Louis A. Vendetti, Louis A. Scinta, Thomas J. Syracuse,
Norbert G. Rausch, George M. Masotti.
Rack Row: Henry Haines, W. Donald Leslie, Wilfred H. Ferguson, Reuben H. Hamman,
Ernest G. Homokay, J. Curtis HellriegelJEugene W. Wallace.

for the impartial and untrammelled utterance of opinion
on any matters pertaining directly or indirectly to its
professed objects . . .
In the fourth number of the B u f f a l o M e d i c a l Journal, Dr. George
N. Burwell (1819-1891) published an abstract of Flint's article on
typhoid which appeared in the American Journal of Medical Sci­
ences, because most physicians did not subscribe to it. This was
Dr. Flint's first conspicuous success, and it is more than probable
that it laid the foundation of his future as a clinician.
In his obituary for James Piatt White, Austin Flint credited the
establishment of the Medical Department of the University of Buffalo
largely to White's exertions. At any rate, these two physicians were
able to attract five professors from Geneva Medical College to form
the first faculty of the University of Buffalo. According to Harvey
Cushing (1934), our faculty for the first five years made "as notable
a faculty of energetic men as one could hope to find anywhere".
Austin Flint served as Professor of Principles and Practice of
Medicine and Clinical Medicine. The Annual Circular for 1846 said:
The Professor of Practice will hold a Clinique at the
College buildings, each day except Sundays, at 4 o'clock,
P.M. at which time counsel will be given and medicines
administered free of charge to the poor. Special attention
will be given to Auscultation and Percussion, and for
this purpose cases of supposed disease of the heart, lungs,
etc. will be examined carefully before the class.
Eruptive diseases will be treated at this Clinique.
Dr. Flint, a protestant, was instrumental in persuading the Right
Rev. John Timon, first Bishop of Buffalo, to purchase property on
Pearl Place (near Virginia Street) to establish a hospital to be managed
by the Sisters of Charity.
56

THE BUFFALO PHYSICIAN

In 1852, Austin Flint left Buffalo to accept a corresponding chair
in the University of Louisville. While there he travelled abroad to
visit hospitals and clinics in Paris during the spring of 1854. Five
letters about his experiences and observations were published in
the Buffalo Medical Journal. In 1856 he again returned to Buffalo
and resumed his connection with the Medical Department of the
University of Buffalo as Professor of Pathology and Clinical Medicine.
He spent the winters of 1858-59, '59-'60 and '60-'61 in New Orleans
where he served as Physician to the Charity Hospital and Professor
of Clinical Medicine. It was there that he first heard the presystolic
murmur which bears his name today. From 1858 to 1860, his son,
Dr. Austin Flint, Jr. was t h e editor a n d proprietor of t h e B u f f a l o
Medical Journal.

In 1859 he left Buffalo and settled in New York City. To bring
an outsider to occupy any position of prominence in a medical com­
munity has always excited jealousy, envy and even enmity. Failure
for Flint was freely predicted and active opposition encountered.
Some of his junior rival consultants seem never to have forgiven
his success. His first appointment was in 1861 as Professor of Path­
ology and Practical Medicine at Long Island College Hospital in
Brooklyn, a position which he held for seven years. In 1861 he was
also appointed one of the physicians to Bellevue Hospital. He was
one of the original members of the Faculty of Bellevue Hospital
Medical College and filled the chair of the Principles and Practice
of Medicine and Clinical Medicine until the time of his death in
1886.
After Flint left Buffalo, the Sisters of Charity recognized the
need for a psychiatric hospital and they appealed to him for
assistance. Flint sold them his farm and farmhouse then at the junc­
tion of Main Street and Scajaquada Creek. In the administrator's

Front Row: Russell J. Catalano, Samuel L. Lieberman, Clarence A. Straubinger, Charles Donatelli, Vincent
L. Rutecki, Richard N. Terry.
Back Row: Norman J. Foit, Chester J. Kaminski, Eustace G. Phillies, Anthony F. Rizzo, Walter L. Sydoriak,
Alfred A. Mitchell, Harry C. Law, Leo J. Doll, Jr.

Class of 1938 at Spring Clinical Days
FALL, 1973

57

office of the present hospital is a copy of the deed dated 8 September
1860. Dr. Flint's yellow brick, two-story farmhouse now houses the
surgical research laboratory, a medical research unit and the hospital
paint shop of The Sisters of Charity Hospital.
What kind of a teacher was Dr. Flint? It was while searching
all possible sources for the answer to this that several errors in dates
regarding his positions and honors were discovered. Who Was Who
in America has Flint founding the University of Buffalo one year
after the Charter was signed and leaving Buffalo two years after
he had already been in New York City. American Medical Bio­
graphies has Flint as Professor of Medical Theory and Practice from
1836-1844 but the Charter for the University was not signed until
1 1 M a y 1 8 4 6 a n d t h e r e w e r e n o t s e v e n e d i t i o n s of h i s P r a c t i c e o f
Medicine. Biography of Eminent American Physicians and Surgeons
has Flint establishing the Buffalo Medical Journal in 1846 when
he wrote and published his first editorial 1 June 1845 and it also
has the university being founded one year after the Charter was
granted. The most accurate accounts of Flint's life and activities
are in two editorials in the Buffalo Medical Journal. Da Costa (1887)
used material from these editorials as a basis for his Biographical
Sketch of Flint. Austin Flint, Sr. was a great physician and a great
teacher who distinctly improved the quality of medical teaching
of that era by his oral lectures and his classic text-books. One editorial
says:
. . This position he achieved, too, without having made
any noteworthy discoveries (Like Morton and Sims), it
was rather his clear and precise way of dealing with

Sitting: Alfred J. Simon, Alexander Slepian, Richard J. Buckley,Kenneth W. Bone, Robert D. Glennie, Jr., Frederick B. Wilkes,
John C. Ninfo, Robert J. Collins.
Second Row: Gertrude S. Swarthout, Adrian J. Pleskow, Richard S. Fletcher, William H. Georgi, Salvatore J. Brucato, John M.
Donohue, Joseph E. Holly, Harold P. Graser.
Back Row: Alfred F. Luhr, Jr., Duncan K. MacLeod, Raymond W. Mitchell, Jr., Ralph E. Smith, Jr., L. Walter Fix, Norman Haber,
Robert C. McCormick, Eugene T. Donovan, Gustave P. Milkey, Charles C. Richards, George H. Selkirk.

Class of 1943 (April) at Spring Clinical Days
58

THE BUFFALO PHYSICIAN

Class of 1943 (December) at Spring Clinical Days

Front Row: Kevin M. O'Gorman, Salvatore J. Colangelo, Morris Unher, William C. Niesen, Edmund M. Tederous, Harold J. Feldman,
Charles J. Tanner, Jr.
Back Row: Paul J. Wolfgruber, Robert D. Kelsey, Anthony J. Mancini, Amos J. Minkel, jr., Payson B. Jacobson, John R. Williams,
Marvin L. Bloom, Joseph J. Ricotta.

the facts already at command — after all, one of the
rarest of faculties — than any tinge given by him to
the doctrine of practice of his time that won him his
pre-eminence ... Yet it can not be said that he was not
an original contributor to our knowledge, for it is difficult
to imagine that anything like our present appreciation
of cardiac murmurs of differences in pitch in resonance,
or of a multitude of facts connected with the diagnosis
of thoracic affections, could, but for him, have been
reached for many years to come . . ."
Flint's most notable text-book was A treatise on the Principles
and Practice of Medicine which went through six editions from 1866
to 1886. A seventh edition was anticipated but never published
because of Flint's death. Over 40,000 copies had been published
before the sixth edition appeared. The London Lancet (12 March
1887) said "Americans may well be proud of having produced a
man whose indefatigable industry and gifts of genius have done
so much to advance medicine ... It has few equals, either in point
of literary excellence, or of scientific learning, and no one can fail
to study its pages without being struck by the lucidity and accuracy
which characterize them . .
The Cincinnati Medical News (Oct.
1886) said, "In every state and territory of this vast country the
book that will be most likely to be found in the office of a medical
man, whether in city, town, village, or at some cross-roads, is Flint's
Practice . . ."

When Flint was called to the Chair of Theory and Practice of
Medicine at the University of Louisville, Samuel D. Gross was Profes­
sor of Surgery. This was the beginning of a warm friendship between
these two eminent men. There they taught each other's son for two
lecture terms and both boys, Austin, Jr. and Samuel W., graduated
FALL, 1973

59

Class of 1948 at Spring Clinical Days

Front Row: Darwin D. Moore, Warren L. Hollis, Cletus J. Regan, Raphael S. Good, Vernon C. Lubs,
Middle Row: Harold L. Graff, Norman Minde, William H. Bloom, Albert P. Sutton, Francis J. Peisel.
Back Row: Seymour P. Zola, Paul Weinberg, Myron Gordon, Lester H. Schiff, Warren H. Hanson,
Daniel J. Fahey, Robert J. Hall, Ansel R. Martin, James G. Robilotto, B. Edward Heckmann,
Richard C. Proplesch.

from Jefferson Medical College in 1857. In his Autobiography, Gross
speaks of Flint:
. . . Tall, handsome, and of many form, with a well mod­
ulated voice of great compass, he is a lecturer at once
clear, distinct, and inspiring. During his hour in the class­
room no student ever falls asleep ... I know of no one
who is so well entitled as Austin Flint, Sr. to be regarded
as the American Laennec.
Gross goes on to say that he had the pleasure of seeing Dr.
Flint elected president of the American Medical Association (188384) after he had nominated him. "In choosing him the Association
honored itself more than it honored the New York veteran physician."
He was president of The New York Academy of Medicine in 1872.
He was chosen to be president of the International Medical Congress
to be held in Washington, D.C. but did not live to do more than
to begin some of the organization. He was corresponding member
of the Academy of Medical Science in Palermo; an Honorary Member
of the Medical Society of London of the British Medical Association;
his name is on the role of Foreign Honorary Members of the Clinical
Society of London, and the American College of Physicians made
him a Fellow in 1868. Yale University made him Doctor of Laws
in 1881.

60

THE BUFFALO PHYSICIAN

The extraordinary care and industry with which he collected
the facts that were to serve as a basis of his work may be judged
by a statement made by Austin Flint, Jr. that his father had begun
his record of cases in 1833 and had filled sixteen thousand nine
hundred and twenty-two folio pages with them. Da Costa said, "a
statement more eloquent in its bare mention than the most elaborate
panegyric on his marvellous industry and untiring energy."
Austin Flint died of apoplexy, 13 March 1886, as he had wished,
rapidly, not lingering or painful. •
References
1. Flint, A. The Reciprocal Duties and Obligations of the Medical Profession and
the Public. Chicago, Eastman, 1844.
2. Flint, A. Account of an epidemic fever which occurred at North Boston, Erie County,
N.Y. during the months of October and November 1843. Am.J.Med. Sci. N.S. 10:
21-35, 1845.
3. Editorial. Austin Flint, M.D., L.L.D. Buffalo Med./. 25: 425-33, 1886.
4. Da Costa, J.M. Biographical Sketch of Dr. Austin Flint. Trans. Coll. Physns. Philad.
3rd Ser., 9: 461-470, 1887.
5. Autobiography of Samuel D. Gross, M.D. Ed. by his sons, Philadelphia, Barrie,
2 Vols., 1887.
6. Potter, W.W., Fifty years of medical journalism in Buffalo. Buffalo Med./., N.S.
35: 65-113, 1895-96.
7. Dictionary of American Biography. New York, Scribners, VI, 471-472, 1931.
8. Genealogy of John Fiske Brown (1901-).

Front Row: James M. Orr, Joseph F. Ruh, Donald L. Ehrenreich, Bertram A. Portin, John W. Handel, Donald Rachow.
Middle Row: John D. Voltmann, Richard J. Nagel, Thomas G. Goeghegan, Stanley L. Cohen, Michael A. Sullivan, Thomas Comerford,
Jr., Marvin Wadler.
Back Row: John N. Strachan, Jr., Howard C. Smith Jr., Jerome E. Hurley, James W. Carlin, Thomas W. Atkins, Raymond M.
Smith, Jr., Albert G. Bickelmann Jr., Robert S. Sobocinski, Herbert W. Simpkins, Milford C. Maloney, Jack Gold.

Class of 1953 at Spring Clinical Days
FALL, 1973

61

Nine
Physicians
Retire

EN MEDICAL FACULTY at the University — nine are physicians, one
an attorney — who are age 70 will retire August 31, after collectively
serving a total of 346 years. Nine were born in Western New York;
eight are Medical School graduates. They are Drs. Marvin A. Block,
John Burke, Clyde W. George, Martin L. Gerstner, Ramsdell Gurney,
L. Edgar Hummel, Joseph G. Krystaf, L. Maxwell Lockie, Meyer H.
Riwchun, and Joseph L. Guariglia (LLB).
Five have served in the department of medicine. Dr. Marvin
A. Block, born in Buffalo and educated here (M'25) is a clinical
assistant professor in medicine who joined the faculty in 1928 as
an assistant. He received the American Medical Association's medal
of achievement for his 25 years of service in the field of alcoholism
and his role in gaining AMA recognition of alcoholism as a disease.
Dr. Clyde W. George, a 1929 alumnus, is a clinical associate
in medicine who joined the faculty in 1943 as an assistant
(medicine/therapeutics). The internist and primary physician to
many was always a volunteer teacher. Buffalo-born and educated
(M'29) Dr. Ramsdell Gurney is a clinical associate professor in
medicine who started in 1932 as an assistant. The Diplomate, Ameri­
can Board of Internal Medicine served as Buffalo General Hospital's
first outpatient department director and as one of the founders of
the Buffalo Medical Group.
Dr. L. Edgar Hummel, born in Darien Center, is a 1931 Harvard
graduate. The clinical assistant professor in medicine has been on
the faculty since 1938 and has always had a keen interest in research.
He retired from the directorship of the Meyer Hospital in January,
1970.

Kneeling: John V. Armenia, Richard R. Romanowski, Elroy E. Anderson, Gaspare A. Alfano, Robert J. Perez.
Second Row: Lucien A. Potenza, Franklin N. Campagna, William L. Glazier, Reinhardt W. Wende, Gary N. Cohen, Anna A. Tracy,
Franklin Zeplowitz, Eugene A. Friedberg.
Third Row: Michael T. Genco, Joseph A. Zizzi, Richard A. Rahner, John P. Murphy, Domonic F. Falsetti, Leo A. Kane, Samuel
Shatkin, Thomas G. Cummiskey, Gerald T. Guerinot.
Back Row: John J. Giardino, John W. Float, James S. Williams, Richard D. Wasson, Michael A. Mazza, Richard C. Boyle, Ronald
E. Batt, Marie L. Kunz, Alfred M. Stein, Melvin M. Brothman.

Class of 1958 at Spring Clinical Days
62

THE BUFFALO PHYSICIAN

Dr. L. Maxwell Lockie, born and educated (PhG'23 and M'28)
in Buffalo, has been a clinical professor in medicine since 1932
when he joined as an assistant. The Associate Fellow of the American
College of Physicians has served as professor/head of the division
of therapeutics since 1939 and has made significant contributions
both locally as well as nationally to the field of rheumatology (ex
officio member, Medical/Scientific Committee, Arthritis and
Rheumatism Foundation; consultant in rheumatology to HEW; chair­
man, executive committee, American Rheumatism Assn.).
Two are Buffalo-born and educated otolaryngologists. Dr. Martin
L. Gerstner (M'29), a clinical associate professor, has served since
1938 when he joined as an assistant. Dr. Joseph G. Krystaf (M'27),
a clinical assistant professor, came to the faculty in 1944 as clinical
associate.
Retiring from the department of surgery is Dr. John Burke. The
clinical associate professor since 1936 (joined as an instructor) was
born in Buffalo and is a Yale alumnus (1928). While serving with
the Marine Corps the Lt. Colonel was assistant and chief of the Surgi­
cal Service of the 23rd General Hospital.
Dr. Meyer H. Riwchun, clinical professor of ophthalmology,
headed the division of ophthalmology at the Children's Hospital
(1960) and has served as co-head of the department of ophthalmology.
The Buffalo-born and educated (M'27) ophthalmologist joined the
faculty in 1934 as an assistant. He is a Diplomate, American Board
of Ophthalmology and a Fellow of the American College of Ophthalmology/Otolaryngology and American College of Surgeons. He is
a past president of the Buffalo Ophthalmologic Society, Buffalo Eye
and Ear Hospital, and Maimonides Medical Society.
Mr. Joseph J. Guariglia, born in Buffalo and a 1928 UB law
school graduate, has served as a lecturer in the department of legal
medicine since 1959 (he joined as an assistant). He has served as
counsel to the Erie County Medical Society and as assistant attorney
to the Buffalo Legal Aid Bureau.
All were honored at the School of Medicine's annual faculty
meeting May 24. •

A $10,000 gift from the estate of the late Elizabeth Crosby Gardner
of Buffalo has been made to the School of Medicine.
Mrs. Gardner, who died in July of 1972, was the daughter of
William H. Crosby, a former treasurer of the University of Buffalo
and a member of its Council. His contributions and those of his
family made possible the construction of Crosby Hall on the U/B
Main St. campus in 1931. Crosby Hall now houses offices and class­
rooms for the School of Management and several modern language
departments.
The donor specified that the $10,000 be used at the discretion
of the University Council for the benefit of its School of Medicine.
The gift was made through the University at Buffalo Foundation,
Inc., a private, non-profit corporation chartered by the New York
State Board of Regents to act as U/B's agent in the soliciting, collecting
and administering of private monies. •
FALL, 1973

63